Dergiler / GORM:Gynecology Obstetrics & Reproductive Medicine / 2012 / Cilt: 18 - Sayı: 1

Clinicopathologic characteristics and reproductive outcomes of patients with borderline ovarian tumors (BOTs): A single institute experience and a review of the literature

Sayfa
26–32
DOI
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Although the recurrence risk in patients who underwent conservative surgery is relatively higher, disease free survival rates are no different than those who had radical surgery

📌 3 Maddede Bu Makale

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Amaç & Hipotez:OBLECTIVES: In borderline ovarian tumor (BOT) cases, evaluating the therapy forms, the percentage of recurrence and survival and the condition of fertility after conservative surgery, for those with a fertil- ity wish.
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Temel Bulgular & Veri:STUDY DESIGN: The files, follow-up forms and pathological reports of 96 cases, diagnosed with BOT, at our clinic, treated between 1994-2009, have been retrospectively evaluated.
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Sonuç & Katkı:Although the recurrence risk in patients who underwent conservative surgery is relatively higher, disease free survival rates are no different than those who had radical surgery
🔬Tür:Araştırma Makalesi
📍Kapsam:2009 Verileri
⚙️Değişkenler:Alan Parametreleri

Abstract

OBLECTIVES: In borderline ovarian tumor (BOT) cases, evaluating the therapy forms, the percentage of recurrence and survival and the condition of fertility after conservative surgery, for those with a fertil- ity wish. STUDY DESIGN: The files, follow-up forms and pathological reports of 96 cases, diagnosed with BOT, at our clinic, treated between 1994-2009, have been retrospectively evaluated. RESULTS: The mean age of the evaluated cases was 39.54±13.4. On the basis of histopathological data, 46 cases (47.9%) had serous and 41 cases (42.7%) had mucinous, and 9 cases (9.4%) had other histological subtypes. 88 cases were in stage I, 2 cases (2.1%) were in stage II and 6 cases (6.2%) were in stage III. 89 (92.7%) cases were operated with laparatomy, 7 (7.3%) cases were operated with laparoscopy. In 52 cases (54.1%), conservative (fertility preserving) surgery was applied (27 cases USO, 8 cases cystectomy, 17 cases USO-staging), in 44 cases (45.8%) radical surgery (in 32 cases, complete staging, TAH-BSO in 11 cases, TAH-USO in 1 case). 26% of the cases (25 cases) underwent postoperative adjuvant chemotherapy. In 39 cases with fertility wish, 8 pregnancy occured after therapy. In the follow-up, 10 cases (10.4%) had recurrence. The rate of recurrence was 4% (2/44) after radical surgery and 15% (8/52) after conservative surgery. The general disease-free survival rate of the cases (DFS) was 89.6%, and there was no significant difference between radical and conservative surgery in view of DFS (95.45% vs 84.62%, p=0.97). CONCLUSION: In cases of borderline ovarian tumor, the best therapy is surgical debulking and the post-operative recurrence rate is generally low. Although the recurrence risk in patients who underwent conservative surgery is relatively higher, disease free survival rates are no different than those who had radical surgery

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Bu Makaleye Atıf Yap

GÜLTEKİN, E., ELMASTAŞ, Ö. G., CINGILLIOĞLU, B., AYAZ, D., YILDIRIM, Y., BOZTOSUN, A. (2012). Clinicopathologic characteristics and reproductive outcomes of patients with borderline ovarian tumors (BOTs): A single institute experience and a review of the literature. GORM:Gynecology Obstetrics & Reproductive Medicine, Cilt: 18 - Sayı: 1, 26–32. https://ajindex.com/articles/213658

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Kaynakça (17)

  1. American Cancer Society. Cancer Facts and Figures 2006. Atlanta: American Cancer Society, 2006
  2. Greenlee RT, Murray T, Bolden S, Wingo PA. Cancer Statistics. 2000. CA Cancer J Clin 2000;50:7-33
  3. Runnebaum IB, Stickeler E. Epidemiological and Moleculer Aspects of Ovarian Cancer Risk. J Cancer Res Clin Oncol 2001;127:73-79
  4. Berker B, Tezcan S. Borderline Ovarian Tumors. T Klin J Gynecol Obst 2002;12:208-212
  5. Tuncer S, Basaran M. Gynecology, reproductive en- docrinology and gynecologic oncology, Ed: Sinan Beksac. Borderline ovarian tumors. MN Gorm 2006;1424-1432 6. Trope CG, Kristensen G, Makar A. Surgery of borderline tumor of the ovary. Semin Surg Oncol 2000;19:69-75
  6. Zanetta G, Rota S, Chiari S, Bonazzi C, Bratina G, Mangioni C. Behavior of Borderline Tumors with particu- lar interest to persistence, recurrence and progression to invasive carcinoma: a prospective study. J Clin Oncol 2001;19:2658-64
  7. Leake JF, Currie JL, Rosenshein NB, Woodruff JD. Long term follow up of serous ovarian tumors of low malignant potential. Gynecol Oncol 1992;47:150-8
  8. Trope C, Kaern J. Management of borderline tumors of the ovary: State of the art. Semin Oncol 1998;5:372-380
  9. Trimble CL, Trimble EL. Management of epithelial ovar- ian tumors of low malignant potential. Gynecol Oncol 1994;55:52-61
  10. Alanbay I. Chemotheray endications in borderline ovarian tumors. T Klin J Med Sci 2007;3:100-104
  11. Taylor HC. Malignant and semimalignant tumors of the ovary. Surg Gynecol Obstet 1929;48:204-30
  12. Casey AC, Bell DA, Lage JM. Epithelial ovarian tumors of borderline malignancy: Long term follow-up. Gynecol Oncol 1993;50:316-22
  13. Barakat RR. Borderline tumors of the ovary. Obstet Gynecol Clin North Am 1994;21:93-105
  14. Ayhan A, Celik H. Borderline ovarian tumors. Textbook of obstetrics and gynecology (Turkish). Editor: Ali Ayhan. 2 nd edition, pp 1291-1298, Gunes Tip Kitapevi, 2008 16. De Iaco P, Ferrero A, Rosati F, Melpignano M, Biglia N, et al. Behaviour of ovarian tumors of low malignant po- tential treated with conservative surgery. Eur J Surg Oncol 2009;35:643-648
  15. Park JY, Kim DY, Kim JH, Kim YM, Kim YT, Nam JH. Surgical management of borderline ovarian tumors: The role of fertility–sparing surgery. Gynecol Oncol 2009; 113:75-82
  16. Tinelli R, Tinelli A, Tinelli FG, Cicinelli E, Malvasi A. Conservative surgery for borderline ovarian tumors: a re- view. Gynecol Oncol 2006;100:185-191
  17. Chao TM, Yen MS, Chao KC, Ng HT. Epithelial ova