Dergiler / Haydarpaşa Numune Medical Journal / 2020 / Cilt: 60 - Sayı: 3

The Neuroectodermal Subtypes of Chiari Malformation: Long-term Results

Sayfa
259–265
DOI
—
🏛️Bu makalenin bibliyografik verileri ve tam metin bağlantısı DergiPark üzerinden sağlanmıştır.
DergiPark Kaydı ↗
✨

Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Therefore, the surgeon should spend more time on dura repair.

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:Introduction: Chiari malformations (CMs) are a heterogeneous group of disorders defined by anatomic anomalies of the cerebellum, brainstem, and craniovertebral junction (CVJ).
📊
Temel Bulgular & Veri:This study aims to establish the de-mographic and clinical features, incidence, surgical procedures, and outcomes in large series of CMs, to investi-gate whether CM-0 is a subgroup of CM, Chiari 1 and 1.5 are different pathologies.
💡
Sonuç & Katkı:Therefore, the surgeon should spend more time on dura repair.
🔬Tür:Araştırma Makalesi
📍Kapsam:2016 Verileri
⚙️Değişkenler:Alan Parametreleri

Özet

Introduction: Chiari malformations (CMs) are a heterogeneous group of disorders defined by anatomic anomalies of the cerebellum, brainstem, and craniovertebral junction (CVJ). This study aims to establish the de-mographic and clinical features, incidence, surgical procedures, and outcomes in large series of CMs, to investi-gate whether CM-0 is a subgroup of CM, Chiari 1 and 1.5 are different pathologies. Methods: In this study, all of the patients were evaluated and operated on for CM between 1985 and 2016. The patients were grouped into various subtypes. Demographic data, additional diseases, clinical features, surgical procedures, complications and outcomes were recorded. Results: In this study, 55 patients who underwent various surgical procedures were evaluated. Their mean age was 0.72±1.17. We detected 26 cases of CM-2 (47.3%), 16 cases of CM-3 (29.1%) and 13 cases of CM-4 (23.6%). When Chiari subtypes were compared, there were statistically significant differences in additional dis-eases, symptom duration, neuro examination, complication rate and hospital stay. Discussion and Conclusion: The findings obtained in this study suggest that the long hospital stay, the presence of SM and short symptom duration are associated with worse outcomes. The dura repair is the most important stage of surgery. Dural tear (CSF fistule) increases the complication rate and mean hospital stay and also causes the worse outcome. Therefore, the surgeon should spend more time on dura repair.

🔖

Bu Makaleye Atıf Yap

SARI, R., BÖLÜKBAŞI, F. H., BAŞARAN, R., EFENDİOĞLU, M., IŞIK, N. (2020). The Neuroectodermal Subtypes of Chiari Malformation: Long-term Results. Haydarpaşa Numune Medical Journal, Cilt: 60 - Sayı: 3, 259–265. https://ajindex.com/articles/204164

📄 Tam Metin PDF Okuyucu

📄

PDF görüntüleyici hazırlanıyor...

Kaynakça (14)

  1. Sarnat HB. Disorders of segmentation of the neural tube: Chiari malformations. Handb Clin Neurol 2008;87:89–103
  2. Carmel PW, Markesbery WR. Early descriptions of the ArnoldChiari malformation. The contribution of John Cleland. J Neurosurg 1972;37:543–7
  3. Pearce JM. Arnold chiari, or "Cruveilhier cleland Chiari" malformation. J Neurol Neurosurg Psychiatry 2000;68:13
  4. Loukas M, Noordeh N, Shoja MM, Pugh J, Oakes WJ, Tubbs RS. Hans Chiari (1851-1916). Childs Nerv Syst. 2008;24:407–9
  5. Furuya K, Sano K, Segawa H, Ide K, Yoneyama H. Symptomatic tonsillar ectopia. J Neurol Neurosurg Psychiatry 1998;64:221– 6
  6. Speer MC, Enterline DS, Mehltretter L, Hammock P, Joseph J, Dickerson M, et al. Review Article: Chiari Type I Malformation with or Without Syringomyelia: Prevalence and Genetics. J Genet Couns 2003;12:297–311
  7. Boyles AL, Enterline DS, Hammock PH, Siegel DG, Slifer SH, Mehltretter L, et al. Phenotypic definition of Chiari type I malformation coupled with high‐density SNP genome screen shows significant evidence for linkage to regions on chromosomes 9 and 15. American Journal of Medical Genetics Part A 2006;40(24):2776–85
  8. Tubbs RS, Griessenauer CJ, Hendrix P, Oakes P, Loukas M, Chern JJ, et al. Relationship between pharyngitis and peri-odontoid pannus: A new etiology for some Chiari I malformations? Clin Anat 2015;28:602–7
  9. Milhorat TH, Bolognese PA, Nishikawa M, McDonnell NB, Francomano CA. Syndrome of occipitoatlantoaxial hypermobility, cranial settling, and chiari malformation type I in patients with hereditary disorders of connective tissue. J Neurosurg Spine 2007;7:601–9
  10. Schijman E. History, anatomic forms, and pathogenesis of Chiari I malformations. Childs Nerv Syst 2004;20:323–8
  11. Caldarelli M, Di Rocco C. Diagnosis of Chiari I malformation and related syringomyelia: radiological and neurophysiological studies. Childs Nerv Syst 2004;20:332–5
  12. Rozenfeld M, Frim DM, Katzman GL, Ginat DT. MRI Findings After Surgery for Chiari Malformation Type I. AJR Am J Roentgenol 2015;205:1086–93
  13. Markunas CA, Tubbs RS, Moftakhar R, Ashley-Koch AE, Gregory SG, Oakes WJ, et al. Clinical, radiological, and genetic similarities between patients with Chiari Type I and Type 0 malformations: Clinical article. Journal of Neurosurgery: Pediatrics, 2012;9:372–8
  14. Vandertop WP, Asai A, Hoffman HJ, Drake JM, Humphreys RP, Rutka JT, et al. Surgical decompression for symptomatic Chiari II malformation in neonates with myelomeningocele. J