The synthesis of a-aminonitriles was successfully accomplished by the 1-pot 3-component reaction of several aldehydes with (S)-a-phenylethylamine and sodium cyanide in water in the presence of montmorillonite K10 and dicationic phosphonium salt under ultrasonic effect with good yields and moderate diastereoselectivities.
📌 3 Maddede Bu Makale
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Amaç & Hipotez:The synthesis of a-aminonitriles was successfully accomplished by the 1-pot 3-component reaction of several aldehydes with (S)-a-phenylethylamine and sodium cyanide in water in the presence of montmorillonite K10 and dicationic phosphonium salt under ultrasonic effect with good yields and moderate diastereoselectivities.
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Temel Bulgular & Veri:The synthesis of a-aminonitriles was successfully accomplished by the 1-pot 3-component reaction of several aldehydes with (S)-a-phenylethylamine and sodium cyanide in water in the presence of montmorillonite K10 and dicationic phosphonium salt under ultrasonic effect with good yields and moderate diastereoselectivities.
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Sonuç & Katkı:The synthesis of a-aminonitriles was successfully accomplished by the 1-pot 3-component reaction of several aldehydes with (S)-a-phenylethylamine and sodium cyanide in water in the presence of montmorillonite K10 and dicationic phosphonium salt under ultrasonic effect with good yields and moderate diastereoselectivities.
The synthesis of a-aminonitriles was successfully accomplished by the 1-pot 3-component reaction of several aldehydes with (S)-a-phenylethylamine and sodium cyanide in water in the presence of montmorillonite K10 and dicationic phosphonium salt under ultrasonic effect with good yields and moderate diastereoselectivities.
Abstract
The synthesis of a-aminonitriles was successfully accomplished by the 1-pot 3-component reaction of several aldehydes with (S)-a-phenylethylamine and sodium cyanide in water in the presence of montmorillonite K10 and dicationic phosphonium salt under ultrasonic effect with good yields and moderate diastereoselectivities.
YILDIRIM, Ç., YOLAÇAN, Ç., AYDOĞAN, F. (2012). Synthesis of a-aminonitriles catalyzed by montmorillonite K10 in the presence of dicationic phosphonium salt in water under ultrasonic effect. Turkish Journal of Chemistry, Cilt: 36 - Sayı: 1, 101–109. https://ajindex.com/articles/185308