KaydedilenlerDerginizi ekleyin

Dergiler / Turkish Journal of Chemistry / 2010 / Cilt: 34 - Sayı: 4

Heterocyclic synthesis using nitrilimines: part 14. Synthesis of new pyrazole derivatives

Hany M. DALLOUL
Sayfa
529–536
Yayın Tarihi
2010-04-01
DOI
—
🏛️Bu makalenin bibliyografik verileri ve tam metin bağlantısı DergiPark üzerinden sağlanmıştır.
DergiPark Kaydı ↗
✨

Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Both analytical and spectroscopic data of all the synthesized compounds are in full agreement with the proposed structures.

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:A new series of 1,3,4,5-tetrasubstituted pyrazoles have been synthesized by the 1,3-dipolar cycloaddition of suitable nitrilimines to 3-propylidene and 3-benzylidene-phthalide.
📊
Temel Bulgular & Veri:A new series of 1,3,4,5-tetrasubstituted pyrazoles have been synthesized by the 1,3-dipolar cycloaddition of suitable nitrilimines to 3-propylidene and 3-benzylidene-phthalide.
💡
Sonuç & Katkı:Both analytical and spectroscopic data of all the synthesized compounds are in full agreement with the proposed structures.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Nitrilimines · 3-dipolar cycloaddition · phthalides

Özet

A new series of 1,3,4,5-tetrasubstituted pyrazoles have been synthesized by the 1,3-dipolar cycloaddition of suitable nitrilimines to 3-propylidene and 3-benzylidene-phthalide. Both analytical and spectroscopic data of all the synthesized compounds are in full agreement with the proposed structures.

Abstract

A new series of 1,3,4,5-tetrasubstituted pyrazoles have been synthesized by the 1,3-dipolar cycloaddition of suitable nitrilimines to 3-propylidene and 3-benzylidene-phthalide. Both analytical and spectroscopic data of all the synthesized compounds are in full agreement with the proposed structures.

🔖

Bu Makaleye Atıf Yap

DALLOUL, H. M. (2010). Heterocyclic synthesis using nitrilimines: part 14. Synthesis of new pyrazole derivatives. Turkish Journal of Chemistry, Cilt: 34 - Sayı: 4, 529–536. https://ajindex.com/articles/185230

📄 Tam Metin PDF Okuyucu

📄

PDF görüntüleyici hazırlanıyor...

Kaynakça (20)

  1. In conclusion, we described the 1,3-dipolar cycloadditions of nitrilimines to some exocyclic oleŞns and the results demonstrated that the aromatization was the driving force for the formation of aromatic pyrazole derivatives. Caramella, P.; Grunanger, P.; in 1,3-Dipolar Cycloaddition Chemistry; A. Padwa, Ed., Wiley Interscience, New York, 1984, pp. 291-319.
  2. Carruthers, W.; Cycloaddition Reaction in Organic Synthesis, Pergamon Press, New York, 1990;
  3. Shawali, A. S.; Parkanyi, C.; J. Heterocycl. Chem. 1980, 17, 833-854;
  4. Tanaka, K.; Maeno, S.; Mitsuhashi, K.; J. Heterocycl. Chem., 22, 565-568;
  5. Shawali, A. S.; Abdelkader, M. H.; Altablawy, F. M.; Tetrahedron 2000, 58, 2875-2880;
  6. Shawali, A. S.; Mosselhi, M. H.; Altablawy, F. M.; Farghaly, T. A.; TawŞk, N. M.; Tetrahedron 2008, 64, 5524-5530;
  7. Shawali, A. S.; Hassaneen, H. M.; Shurrab, N. Kh.; Tetrahedron 2008, 64, 10339-10343;
  8. Abunada, N. M.; Hassaneen, H. M.; Kandile, N, G.; Miqdad, A. O.; Molecules 2008, 13, 1011-1024.
  9. Hassaneen, H. M.; Hilal, R. H.; Elwan, N. M.; Harhash, A.; Shawali, A. S.; J. Heterocycl. Chem. 1984, 21, 1013 Agocs, A.; Benyei, A.; Somogy, L.; Herczegh, P.; Tetrahedron: Asymmetry 1998, 9, 3359-3363.
  10. Donohue, S. R.; Halldin, C.; Pike, V. W.; Tetrahedron Lett. 2008, 49, 2789- 2791; Mernyak, E.; Kozma, E.; Hetenyi, A.; Mark, L.; Schneider, G.; Wolfling, J.; Steroids 2009, 74, 520-525.
  11. Kerbal, A.; Tshiamala, K.; Vebrel, J.; Laude, B.; Mercier, M. F.; Bull. Soc, Chim. Belg. 1991, 100, 159-168.
  12. Jedlovska, E.; Levai, A.; Toth, G.; Balazs, B.; Fisera, L.; J. Heterocycl. Chem. 1999, 36, 1087-1090.
  13. Mishriky, N.; Girgis, A. S.; Ibrahim, Y. A.; J. Chem. Res. S, 2000, 1, 2-3.
  14. Elguero, J.; Goya, P.; Jagerovic, N.; Silva, A. M. S.; Targets Heterocycl. Syst. 2002, 6, 52-98.
  15. HenningŞeld, J. E.; Fant, R. V.; Buchhalter, A. R.; Stitzer, M. L.; CA Cancer J. Clin. 2005, 55, 281-299.
  16. Glass, M.; Van Dellen, A.; Blakemoore, C.; Hannan, A. J.; Faull, R. L.; Neuroscience 2004, 123, 207-212;
  17. J. H. M. Lange, C. G. Kruse, Drug Discovery Today 2005, 10, 693-702.
  18. Eriksson, B. I.; Quinlan, D. J.; Drugs 2006, 66, 1411-1429.
  19. Oh, L. M.; Tetrahedron Lett. 2006, 47, 7943-7946.
  20. Penning, T. D.; Talley, J. J.; Bertenshaw, S. R.; Carter, J. S.; Collins, P. W.; Docter, S.; Graneto, M. J.; Lee, I. F.; Malecha, J. W.; Miyashiro, J. M.; Rogers, R. S.; Rogier, D. J.; Yu, S. S.; Anderson, G. D.; Burton, E. G.; Cogburn, J. N.; Gregory, S. A.; Koboldt, C. M.; Perkins, W. E.; Seibert, K.; Veenhuizen, A. W.; Zhang, Y. Y.; Isakson, P. C.; J.