Dergiler / Turkish Journal of Chemistry / 2008 / Cilt: 32 - Sayı: 5

Synthesis and Antifungal Activity of Some Novel N-(4-Phenyl-3-aroylthiazol-2(3H)-ylidene) Substituted Benzamides

Sayfa
585–592
Yayın Tarihi
2008-05-01
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Some of the synthesized compounds were assayed in vitro for their antifungal activity and were found to exhibit low to moderate activity.

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Amaç & Hipotez:Variously substituted N-(4-phenyl-3-aroylthiazol-2(3H)-ylidene)benzamides (2a-t) were prepared by base-catalyzed cyclization of corresponding 1-aroyl-3-aryl thioureas with acetophenone in the presence of bromine.
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Temel Bulgular & Veri:Variously substituted N-(4-phenyl-3-aroylthiazol-2(3H)-ylidene)benzamides (2a-t) were prepared by base-catalyzed cyclization of corresponding 1-aroyl-3-aryl thioureas with acetophenone in the presence of bromine.
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Sonuç & Katkı:Some of the synthesized compounds were assayed in vitro for their antifungal activity and were found to exhibit low to moderate activity.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:N-(4-phenyl-3-aroylthiazol-2(3H)-ylidene) substituted benzamides · antifungal · N-(4-phenyl-3-aroylthiazol-2(3H)-ylidene) substituted benzamides

Özet

Variously substituted N-(4-phenyl-3-aroylthiazol-2(3H)-ylidene)benzamides (2a-t) were prepared by base-catalyzed cyclization of corresponding 1-aroyl-3-aryl thioureas with acetophenone in the presence of bromine. Some of the synthesized compounds were assayed in vitro for their antifungal activity and were found to exhibit low to moderate activity.

Abstract

Variously substituted N-(4-phenyl-3-aroylthiazol-2(3H)-ylidene)benzamides (2a-t) were prepared by base-catalyzed cyclization of corresponding 1-aroyl-3-aryl thioureas with acetophenone in the presence of bromine. Some of the synthesized compounds were assayed in vitro for their antifungal activity and were found to exhibit low to moderate activity.

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Bu Makaleye Atıf Yap

SAEED, A., ZAMAN, S., JAMIL, M., MIRZA, B. (2008). Synthesis and Antifungal Activity of Some Novel N-(4-Phenyl-3-aroylthiazol-2(3H)-ylidene) Substituted Benzamides. Turkish Journal of Chemistry, Cilt: 32 - Sayı: 5, 585–592. https://ajindex.com/articles/184986

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