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Dergiler / KONURALP TIP DERGİSİ / 2020 / Cilt: 12 - Sayı: 1

Are the conventional risk factors still valid for acute myeloid leukemia patients?

Abdulkerim YILDIZ
Senem MARAL
Murat ALBAYRAK
Çiğdem PALA
Pınar CÖMERT
Hacer Berna AFACAN ÖZTÜRK
Osman ŞAHİN
Sayfa
5–11
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Conclusion: In addition to genetic and molecular features, which are expensive and not easily available, the age and leukocyte count of AML patients remain important as prognostic factors.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Objective: The aim of this study was to investigate the survival data of patients with acute myeloid leukemia (AML) and to determine the risk factors that can be easily evaluated.
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Temel Bulgular & Veri:Method: A retrospective analysis was made of the AML patients admitted to our center between 2009-2018.
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Sonuç & Katkı:Conclusion: In addition to genetic and molecular features, which are expensive and not easily available, the age and leukocyte count of AML patients remain important as prognostic factors.
🔬Tür:Araştırma Makalesi
📍Kapsam:2009-2018 Verileri
⚙️Değişkenler:leukemia · survival · age

Abstract

Objective: The aim of this study was to investigate the survival data of patients with acute myeloid leukemia (AML) and to determine the risk factors that can be easily evaluated. Method: A retrospective analysis was made of the AML patients admitted to our center between 2009-2018. Demographic data and disease data were analyzed and response rates, overall survival (OS) and progression-free survival (PFS) rates were calculated. Factors affecting survival were determined using Cox-regression analysis. Results: A total of 119 patients were included in the study during the 9-year study period. Of these, 21 patients had secondary AML and 11 had acute promyelocytic leukemia (APL). The mean follow-up period was 12.43 ± 15.63 months. OS of all patients was 9.20 months and PFS was 7.23 months. Age and leukocyte count at the time of diagnosis were found to have a significant impact on both OS and PFS (p <0.05). Conclusion: In addition to genetic and molecular features, which are expensive and not easily available, the age and leukocyte count of AML patients remain important as prognostic factors.

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Bu Makaleye Atıf Yap

YILDIZ, A., MARAL, S., ALBAYRAK, M., PALA, Ç., CÖMERT, P., ÖZTÜRK, H. B. A., ŞAHİN, O. (2020). Are the conventional risk factors still valid for acute myeloid leukemia patients?. KONURALP TIP DERGİSİ, Cilt: 12 - Sayı: 1, 5–11. https://ajindex.com/articles/164666

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Kaynakça (14)

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