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Dergiler / Ağrı Tıp Fakültesi Dergisi / 2026 / Cilt: 4 Sayı: 3

Antioksidanlar Üremede Her Zaman Faydalı mıdır? Hayvan Modellerinden Elde Edilen Kanıtların Yeniden Gözden Geçirilmesi

Are Antioxidants Always Beneficial in Reproduction? Rethinking Evidence from Animal Models

Oya Korkmaz(MALATYA TURGUT ÖZAL ÜNİVERSİTESİ, TIP FAKÜLTESİ)0000-0003-2923-5869
Sayfa
132–133
Yayın Tarihi
2026-10-02
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In accordance with the journal's Instructions for Authors, Letters to the Editor do not require an abstract.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:This article is submitted as a Letter to the Editor.
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Temel Bulgular & Veri:This article is submitted as a Letter to the Editor.
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Sonuç & Katkı:In accordance with the journal's Instructions for Authors, Letters to the Editor do not require an abstract.
🔬Tür:Editöre Mektup
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Oksidatif stres · Antioksidanlar · Redoks dengesi

Özet

This article is submitted as a Letter to the Editor. In accordance with the journal's Instructions for Authors, Letters to the Editor do not require an abstract.

Abstract

Bu yazı Editöre Mektup türünde sunulmuştur. Derginin Yazım Kuralları uyarınca Editöre Mektup türündeki yazılarda özet bulunmamaktadır.

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Bu Makaleye Atıf Yap

Korkmaz, O. (2026). Antioksidanlar Üremede Her Zaman Faydalı mıdır? Hayvan Modellerinden Elde Edilen Kanıtların Yeniden Gözden Geçirilmesi. Ağrı Tıp Fakültesi Dergisi, Cilt: 4 Sayı: 3, 132–133. https://doi.org/10.61845/agrimedical.1984603

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Kaynakça (10)

  1. Aitken RJ, Bromfield EG, Gibb Z. Oxidative stress and reproductive function: The impact of oxidative stress on reproduction: a focus on gametogenesis and fertilization. Reproduction. 2022;164(6):F79-F94. https://doi.org/10.1530/REP-22-0126
  2. Sunuwar S, Heo YS. Reactive oxygen species in embryo development: Sources, impacts, and implications for in vitro culture systems. Life (Basel). 2026;16(1):136. https://doi.org/10.3390/life16010136
  3. Mauchart P, Vass RA, Nagy B, Sulyok E, Bódis J, Kovács K. Oxidative stress in assisted reproductive techniques, with a focus on an underestimated risk factor. Curr Issues Mol Biol. 2023;45(2):1272-1286. https://doi.org/10.3390/cimb45020083
  4. Song J, Xiao L, Zhang Z, Wang Y, Kouis P, Rasmussen LJ, et al. Effects of reactive oxygen species and mitochondrial dysfunction on reproductive aging. Front Cell Dev Biol. 2024;12:1347286. https://doi.org/10.3389/fcell.2024.1347286
  5. Cao B, Qin J, Pan B, Qazi IH, Ye J, Fang Y, et al. Oxidative stress and oocyte cryopreservation: Recent advances in mitigation strategies involving antioxidants. Cells. 2022;11(22):3573. https://doi.org/10.3390/cells11223573
  6. Khan MZ, Khan A, Huang B, Wei R, Kou X, Wang X, et al. Bioactive compounds protect mammalian reproductive cells from xenobiotics and heat stress-induced oxidative distress via Nrf2 signaling activation: A narrative review. Antioxidants (Basel). 2024;13(5):597. https://doi.org/10.3390/antiox13050597
  7. Signorini C, Saso L, Ghareghomi S, Telkoparan-Akillilar P, Collodel G, Moretti E. Redox homeostasis and Nrf2-regulated mechanisms are relevant to male infertility. Antioxidants (Basel). 2024;13(2):193. https://doi.org/10.3390/antiox13020193
  8. Dutta S, Sengupta P, Roychoudhury S, Chakravarthi S, Wang CW, Slama P. Antioxidant paradox in male infertility: 'A blind eye' on inflammation. Antioxidants (Basel). 2022;11(1):167. https://doi.org/10.3390/antiox11010167
  9. Agarwal A, Mostafa T, Al Hashimi M, Çayan S, Pescatori E, Singh K, et al. Global Andrology Forum clinical guidelines on antioxidant use in the treatment of male infertility. World J Mens Health. 2026;44:e3. https://doi.org/10.5534/wjmh.250290
  10. Zhang T, Lin M, Wang C, Zhou J. Mechanisms of follicular atresia: Focus on apoptosis, autophagy, and ferroptosis. Front Endocrinol (Lausanne). 2025;16:1603467. https://doi.org/10.3389/fendo.2025.1603467