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Dergiler / Turkish Journal of Analytical Chemistry / 2026 / Cilt: 7 Sayı: 2

Sülfonil-1H-1,2,3-triazollerin sentezi, karakterizasyonu ve antioksidan aktivitesi

Synthesis, characterization and antioxidant activity of sulfonyl-1H-1,2,3-triazoles

Fatih Çelik(KARADENİZ TEKNİK ÜNİVERSİTESİ)0000-0001-5510-3494
Sayfa
176–181
Yayın Tarihi
2025-05-31
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Compounds 7 and 10 emerged as the most potent antioxidant candidates, displaying the strongest effects in both assays.

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Amaç & Hipotez:3-methoxy-4-((1-tosyl-1H-1,2,3-triazol-4-yl)methoxy)benzaldehyde (3), 4-((1-(ethylsulfonyl)-1H-1,2,3-triazol-4-yl) methoxy) benzaldehyde (6), 4-((1-((4-chloro phenyl) sulfonyl)-1H-1,2,3-triazol-4-yl) methoxy) benzaldehyde (9), 4-((4-((1-(ethylsulfonyl)-1H-1,2,3-triazol-4-yl) methoxy) benzylidene) amino)phenol (7), 4-((4-((1-((4-chlorophenyl) sulfonyl)-1H-1,2,3-triazol-4-yl) methoxy) benzylidene) amino) phenol (10), 4-((4-((1-tosyl-1H-1,2,3-triazol-4-yl) methoxy) benzylidene)amino) phenol (12) were synthesized.
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Temel Bulgular & Veri:The compounds were characterized by FTIR, 1H-NMR and 13C-NMR spectroscopic methods.
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Sonuç & Katkı:Compounds 7 and 10 emerged as the most potent antioxidant candidates, displaying the strongest effects in both assays.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:3-triazol · organik sentez · antioksidan aktivite

Özet

3-methoxy-4-((1-tosyl-1H-1,2,3-triazol-4-yl)methoxy)benzaldehyde (3), 4-((1-(ethylsulfonyl)-1H-1,2,3-triazol-4-yl) methoxy) benzaldehyde (6), 4-((1-((4-chloro phenyl) sulfonyl)-1H-1,2,3-triazol-4-yl) methoxy) benzaldehyde (9), 4-((4-((1-(ethylsulfonyl)-1H-1,2,3-triazol-4-yl) methoxy) benzylidene) amino)phenol (7), 4-((4-((1-((4-chlorophenyl) sulfonyl)-1H-1,2,3-triazol-4-yl) methoxy) benzylidene) amino) phenol (10), 4-((4-((1-tosyl-1H-1,2,3-triazol-4-yl) methoxy) benzylidene)amino) phenol (12) were synthesized. The compounds were characterized by FTIR, 1H-NMR and 13C-NMR spectroscopic methods. The antioxidant properties of the compounds were evaluated using two widely accepted methodologies assays (DPPH and FRAP). Compounds 7 and 10 emerged as the most potent antioxidant candidates, displaying the strongest effects in both assays.

Abstract

3-methoxy-4-((1-tosyl-1H-1,2,3-triazol-4-yl)methoxy)benzaldehyde (3), 4-((1-(ethylsulfonyl)-1H-1,2,3-triazol-4-yl) methoxy) benzaldehyde (6), 4-((1-((4-chloro phenyl) sulfonyl)-1H-1,2,3-triazol-4-yl) methoxy) benzaldehyde (9), 4-((4-((1-(ethylsulfonyl)-1H-1,2,3-triazol-4-yl) methoxy) benzylidene) amino)phenol (7), 4-((4-((1-((4-chlorophenyl) sulfonyl)-1H-1,2,3-triazol-4-yl) methoxy) benzylidene) amino) phenol (10), 4-((4-((1-tosyl-1H-1,2,3-triazol-4-yl) methoxy) benzylidene)amino) phenol (12) were synthesized. The compounds were characterized by FTIR, 1H-NMR and 13C-NMR spectroscopic methods. The antioxidant properties of the compounds were evaluated using two widely accepted methodologies assays (DPPH and FRAP). Compounds 7 and 10 emerged as the most potent antioxidant candidates, displaying the strongest effects in both assays.

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Bu Makaleye Atıf Yap

Çelik, F. (2025). Sülfonil-1H-1,2,3-triazollerin sentezi, karakterizasyonu ve antioksidan aktivitesi. Turkish Journal of Analytical Chemistry, Cilt: 7 Sayı: 2, 176–181. https://doi.org/10.51435/turkjac.1665889

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