Dergiler / Ege Klinikleri Tıp Dergisi / 2019 / Cilt: 57 - Sayı: 3

Predictive value of Neutrophil Lymphocyte Ratio (NLR) and Glasgow Prognostic Index (GPI) for complications and length of hospital stay after bowel resection in Crohn's Disease

Nötrofil-Lenfosit Oranı(NLR) ve Glasgow Prognostic Index (GPI)’in, Crohn Hastalığında Postoperatif Komplikasyon ve Hastanede Kalış Süresi Üzerine Etkisi

Sayfa
221–225
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Additionally, NLR is a good parameter to predict morbidity in complicated CD including intraabdominal abscess, enterocutanous or enteroenteric fistula.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Aim:Crohn Disease (CD) is a chronic and often progressive disease that affects the quality of life of the patient.
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Temel Bulgular & Veri:Although the primary treatment is considered to be medical, approximately 70% of patients need surgical intervention(s) during their lifetime.There are limited numbers of studies evaluating the factors affecting postoperative morbidity and length of hospital stay (LOS) and evaluating correlation between postoperative septic complications and Glasgow Prognostic Index (GPI) in CD patients.
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Sonuç & Katkı:Additionally, NLR is a good parameter to predict morbidity in complicated CD including intraabdominal abscess, enterocutanous or enteroenteric fistula.
🔬Tür:Araştırma Makalesi
📍Kapsam:2012 Verileri
⚙️Değişkenler:Alan Parametreleri

Özet

Aim:Crohn Disease (CD) is a chronic and often progressive disease that affects the quality of life of the patient. Although the primary treatment is considered to be medical, approximately 70% of patients need surgical intervention(s) during their lifetime.There are limited numbers of studies evaluating the factors affecting postoperative morbidity and length of hospital stay (LOS) and evaluating correlation between postoperative septic complications and Glasgow Prognostic Index (GPI) in CD patients. In this study, we aimed to evaluate the impact of simple blood tests and GPI on morbidity and LOS in CD patients who underwent surgery. Method: A total of 43 patients who underwent elective bowel resection due to CD in our clinic between 2012 and 2017 were included in the study. Postoperative complications and LOS were recorded. The effecting parameters on the LOS and postoperative complications were evaluated statistically. Results: The postoperative morbidity rate was 32.5% (n=14) and there was no mortality. The blood parameters and GPI score were found not to have statistical significance on the complication rates. The mean LOS was 8.1 (3-30) days. The lymphocyte count and NLR value were significantly predictive markers for the LOS (p<0.05). The LOS and neutrophil-lymphocyte ratio (NLR) were found to be statistically longer and higher, respectively, in complicated patients (p<0.05). Conclusion: NLR and lymphocyte are good predictors to evaluate postoperative LOS. Additionally, NLR is a good parameter to predict morbidity in complicated CD including intraabdominal abscess, enterocutanous or enteroenteric fistula.

Abstract

Amaç: Crohn Hastalığı (CH), hastanın yaşam kalitesini etkileyen kronik ve genellikle progresyonlarla seyreden bir hastalıktır. Hastalığın öncelikle tedavisi tıbbi olmakla birlikte, hastaların yaklaşık% 70'i yaşamları boyunca cerrahi girişime ihtiyaç duyar. Crohn hastalarında postoperatif morbidite ve hastanede kalış süresini etkileyen faktörleri ve postoperatif septik komplikasyonlar ile Glasgow Prognostik İndeksi (GPI) arasındaki ilişkiyi değerlendiren sınırlı sayıda çalışma vardır. Bizde çalışmamızda, basit kan testlerinin ve GPI'nin cerrahi uygulanan Crohn hastalarında morbidite ve hastanede kalış süresi üzerindeki etkisini değerlendirmeyi amaçladık. Materyal ve Metod: Çalışmamıza kliniğimizde 2012-2017 yılları arasında CH nedeniyle elektif barsak rezeksiyonu yapılan toplam 43 hasta alındı. Postoperatif komplikasyonlar ve hastanede kalış süresi kaydedildi. Hastanede kalış süresi ve postoperatif komplikasyonlar üzerine etki eden demografik özellikleri, basit kan testleri ve hastalık lokalizasyonu istatistiksel olarak değerlendirildi. Bulgular: Postoperatif morbidite oranı% 32,5 (n = 14) idi ve mortalite görülmedi. Kan parametreleri ve GPI skoru komplikasyon oranları üzerinde istatistiksel olarak anlamlı bulunmadı. Hastanede yatış süresi ortalama 8.1 (3-30) gündü. Lenfosit ve NLR değerlerinin hastanede kalış süresi konusunda anlamlı prediktif parametreler olduğu görüldü (p<0.05). Komplikasyon görülen hastalarda hastanede kalış süresi ve nötrofil- lenfosit oranı (NLR) sırasıyla istatistiksel olarak daha uzun ve yüksek bulundu (p <0,05). Sonuç: NLR ve lenfosithastanede kalış süresini öngörmede iyi bir belirleyicidir. Aynı zamanda, NLR intraabdominal apse, enterokutanöz veya enteroenterik fistül içeren komplike CH'da morbiditeyi öngörmede iyi bir parametredir.

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Bu Makaleye Atıf Yap

GÜR, E. Ö., KARAİSLİ, S., DİLEK, O. N., ACAR, T., HACIYANLI, S., TAVUSBAY, C., HACIYANLI, M. (2019). Predictive value of Neutrophil Lymphocyte Ratio (NLR) and Glasgow Prognostic Index (GPI) for complications and length of hospital stay after bowel resection in Crohn's Disease. Ege Klinikleri Tıp Dergisi, Cilt: 57 - Sayı: 3, 221–225. https://ajindex.com/articles/150645

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