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Dergiler / International Journal of Innovative Research and Reviews / 2019 / Volume: 3 Issue: 2

Unrevealing of the Effect of Olfactory Bulb Lesion on Histomorphological Changes in Sublingual Glands: An Experimental Study

Mehmetnuri Koçak(Ataturk University Department of Neurology, Erzurum, TURKEY)
Mehmet Dumlu Aydın(Ataturk University Department of Neurochirurgie, Erzurum, TURKEY)
Zülküf Kaya(Ataturk University Department of Ear, Nose and Throat, Erzurum, TURKEY)
Erdem Karadeniz(Ataturk University Department of General Surgery, Erzurum, TURKEY)
Atıf Bayramoğlu(Ataturk University Department of Emergency, Erzurum, TURKEY)
Ali Ahıskalıoğlu(Ataturk University Department of Anesthesiology and Reanimation, Erzurum, TURKEY)
Nazan Aydın(UskudarUniversity Faculty of Humanities and Social Sciences, Department of Psychology, Istanbul, TURKEYv)
Tuba Demirci(Ataturk University Department of Histology, Erzurum, TURKEY)
Sayfa
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Yayın Tarihi
2019-12-15
DOI
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Yapay Zeka Hızlı Bakış & Çıkarımlar

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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

This study suggests that OBL may be responsible for sublingual gland degeneration, which has not been stated so far.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:This study was performed to examine basic neuropathological mechanisms of undetermined effects of olfactory bulb lesion in sublingual glands.
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Temel Bulgular & Veri:Twenty-six adult rats were randomized in three groups as control group (Group I, n=8), Sham group (Group II, n=7) and olfactory bulb lesion (OBL) group (Group III, n=11), and they all observed for the duration of eight weeks and finally euthanized.
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Sonuç & Katkı:This study suggests that OBL may be responsible for sublingual gland degeneration, which has not been stated so far.
🔬Tür:Research Article
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Olfaction · Olfactory Bulb Lesion · Sublingual Gland

Abstract

This study was performed to examine basic neuropathological mechanisms of undetermined effects of olfactory bulb lesion in sublingual glands. Twenty-six adult rats were randomized in three groups as control group (Group I, n=8), Sham group (Group II, n=7) and olfactory bulb lesion (OBL) group (Group III, n=11), and they all observed for the duration of eight weeks and finally euthanized. The olfactory bulbs of rat brains and sublingual glands (SLG), were extracted bilaterally. Samplings stained with hematoxylin/eosin and TUNEL stains to assess the stereogical olfactory bulbs volume loss degrees, and follicular volume values (FVV) of SLG per cubic centimeters. The estimated mean volumes of olfactory bulbs were as 4.87±0.33/mm3 in group I, 4.32±0.43/mm3 in group II, and 2.12±0.19/mm3 in group III (p<0.0001 and p<0.0005; in Group III vs. I, Group III vs. II, respectively). The mean volumes of FVV and degenerated neuron density of SLG were 215±56×106µm3/cm3 and 13±3/mm3 in Group I, 193 ± 44×106µm3/cm3 and 62±11/mm3 in Group II (p<0.005), 134±27×106 µm3/cm3 and 346±83/mm3 in Group III (p<0.0001 and p<0.0005; in Group III vs. I, Group III vs. II, respectively). This study suggests that OBL may be responsible for sublingual gland degeneration, which has not been stated so far.

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Bu Makaleye Atıf Yap

Koçak, M., Aydın, M. D., Kaya, Z., Karadeniz, E., Bayramoğlu, A., Ahıskalıoğlu, A., Aydın, N., Demirci, T. (2019). Unrevealing of the Effect of Olfactory Bulb Lesion on Histomorphological Changes in Sublingual Glands: An Experimental Study. International Journal of Innovative Research and Reviews, Volume: 3 Issue: 2. https://ajindex.com/articles/1496471

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