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Dergiler / International Journal of Chemistry and Technology / 2026 / Issue: 10

Development of a Phthalocyanine-Based PVC Membrane Potentiometric Sensor for the Determination of Imipramine

Müge Karadaş Aksar(YUZUNCU YIL UNIVERSITY, FACULTY OF SCIENCE)0009-0002-8616-6150
Gülşah Saydan Kanberoğlu(YUZUNCU YIL UNIVERSITY, FACULTY OF SCIENCE)0000-0003-4265-6086
Mehmet Salih Ağırtaş(YUZUNCU YIL UNIVERSITY, FACULTY OF SCIENCE)0000-0003-1296-2066
Sayfa
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Yayın Tarihi
2026-06-15
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

The sensor performed well with a recovery of 98.4%.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Imipramine is a tricyclic antidepressant.
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Temel Bulgular & Veri:Overdose of imipramine may cause gastrointestinal upset, dizziness, blurred vision, increased appetite, drowsiness, constipation, dry mouth, urinary retention, narrow-angle glaucoma, and delirium.
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Sonuç & Katkı:The sensor performed well with a recovery of 98.4%.
🔬Tür:Research Article
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Imipramine · phthalocyanine · potentiometric sensor

Abstract

Imipramine is a tricyclic antidepressant. Overdose of imipramine may cause gastrointestinal upset, dizziness, blurred vision, increased appetite, drowsiness, constipation, dry mouth, urinary retention, narrow-angle glaucoma, and delirium. It can cause life-threatening side effects, particularly severe hypotension, coma, hyperactive reflexes, cardiac dysrhythmias, convulsions, and hypothermia confusion. Therefore, the development of a sensitive, reliable, low-cost, and simple method such as potentiometry for the determination of IMIP (imipramine) is of great importance. In this study, a phthalocyanine derivative, [2,10,16,24-tetrakis{9,9-bis(4-oxyphenylfluorene)phthalonitrile}phthalocyanine cobalt(II) (BS-Co-1)], was used as the ionophore in the structure of the imipramine-selective sensor developed. The sensor demonstrated high selectivity towards imipramine, wide linear working range (5.0×10-8 to 1.0×10-2 mol l-1), wide pH working range (2.18-7.38), short response time (20 seconds), and high repeatability. Furthermore, the analytical application of the sensor has been carried out in a commercial drug. The sensor performed well with a recovery of 98.4%.

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Bu Makaleye Atıf Yap

Aksar, M. K., Kanberoğlu, G. S., Ağırtaş, M. S. (2026). Development of a Phthalocyanine-Based PVC Membrane Potentiometric Sensor for the Determination of Imipramine. International Journal of Chemistry and Technology, Issue: 10. https://doi.org/10.32571/ijct.1868961

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