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Dergiler / Bilge International Journal of Science and Technology Research / 2026 / Cilt: 4 Sayı: 1

Hydrodistillation of Nigella Sativa Seed and Analysis of Thymoquinone with HPLC and GC-MS

Ümit Erdoğan(ısparta uygulamalı bilimler üniversitesi)0000-0002-6627-4472
Mustafa Yılmazer(SÜLEYMAN DEMİREL ÜNİVERSİTESİ)0000-0002-3274-6718
Sabri Erbaş(ısparta uygulamalı bilimler üniversitesi)0000-0003-0691-6127
Sayfa
27–30
Yayın Tarihi
2020-03-31
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Sufficient analytical work was performed with this method and the results were shown.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:N. sativa seeds, commonly known as black seeds, are for headaches in traditional medicine by many Asian, Middle Eastern and Far Eastern countries.
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Temel Bulgular & Veri:The proportion of thymoquinone passing into the aromatic water show that it is necessary to consume the correct amount of water and essential oil, which is significantly measurable by GC MS and HPLC.
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Sonuç & Katkı:Sufficient analytical work was performed with this method and the results were shown.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Nigella Sativa · GC-MS · Hydrodistillation

Abstract

N. sativa seeds, commonly known as black seeds, are for headaches in traditional medicine by many Asian, Middle Eastern and Far Eastern countries. It is used to treat cough, abdominal pain, diarrhea, asthma, rheumatism and other diseases. The seeds contain both fixed and essential oils, proteins, alkaloids and saponin. Much of the biological activity of the seeds has been shown to be due to thymoquinone, the major component of the essential oil, but which is also present in the fixed oil. The essential oil of black cumin seeds, Nigella sativa L., was tested for a possible antioxidant activity. In this study, we measured the amount of thymoquinone compound in distilled water taken from aromatic water. The proportion of thymoquinone passing into the aromatic water show that it is necessary to consume the correct amount of water and essential oil, which is significantly measurable by GC MS and HPLC. Thymoquinone was dedected 790 ppm in aromatic water and 45.78% in essential oil. Sufficient analytical work was performed with this method and the results were shown.

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Bu Makaleye Atıf Yap

Erdoğan, Ü., Yılmazer, M., Erbaş, S. (2020). Hydrodistillation of Nigella Sativa Seed and Analysis of Thymoquinone with HPLC and GC-MS. Bilge International Journal of Science and Technology Research, Cilt: 4 Sayı: 1, 27–30. https://doi.org/10.30516/bilgesci.688845

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Kaynakça (23)

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