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Dergiler / Anatomy / 2017 / Cilt: 11 - Sayı: 3

Single dose ketamine injection affects activation of cells in the nucleus accumbens of prenatally stressed rats

Elif Polat ÇORUMLU
Osman Özcan AYDIN
EMEL ULUPINAR
Dergi
Anatomy
Sayfa
115–120
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

In this study, we aimed to investigate the effects of single-dose ketamine application in the activation of cells in the NAc of prenatally stressed rats.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Objectives: The nucleus accumbens (NAc) has recently been implicated in the pathophysiology of depression.
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Temel Bulgular & Veri:In animals displaying depressive-like behavior following chronic stress exposure, glutamatergic transmission increases in the NAc.
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Sonuç & Katkı:In this study, we aimed to investigate the effects of single-dose ketamine application in the activation of cells in the NAc of prenatally stressed rats.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:c-Fos · ketamine · nucleus accumbens

Abstract

Objectives: The nucleus accumbens (NAc) has recently been implicated in the pathophysiology of depression. In animals displaying depressive-like behavior following chronic stress exposure, glutamatergic transmission increases in the NAc. NMDA receptor antagonist ketamine act as an antidepressant, especially in treatment-resistant cases. In this study, we aimed to investigate the effects of single-dose ketamine application in the activation of cells in the NAc of prenatally stressed rats.

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Bu Makaleye Atıf Yap

ÇORUMLU, E. P., AYDIN, O. Ö., ULUPINAR, E. (2017). Single dose ketamine injection affects activation of cells in the nucleus accumbens of prenatally stressed rats. Anatomy, Cilt: 11 - Sayı: 3, 115–120. https://ajindex.com/articles/146132

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Kaynakça (15)

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