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Dergiler / Ahi Evran Tıp Dergisi / 2022 / Volume: 6 Issue: 3

Parkinson Hastalığında D Vitamini Düzeyinin Hastalık Şiddeti, Denge ve Düşme ile İlişkisi

The Relationship of Vitamin D Levels with Disease Severity, Balance, and Falls in Parkinson’s Disease

Merve Damla Korkmaz(İSTANBUL KANUNİ SULTAN SÜLEYMAN SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ)0000-0003-2422-5709
Sayfa
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Yayın Tarihi
2022-12-25
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Amaç: Parkinson hastalığında serum D vitamini düzeyleri ile hastalık şiddeti, denge sorunları ve düşme ve düşme korkusu arasındaki ilişkiyi değerlendirmek.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Amaç: Parkinson hastalığında serum D vitamini düzeyleri ile hastalık şiddeti, denge sorunları ve düşme ve düşme korkusu arasındaki ilişkiyi değerlendirmek.
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Temel Bulgular & Veri:Amaç: Parkinson hastalığında serum D vitamini düzeyleri ile hastalık şiddeti, denge sorunları ve düşme ve düşme korkusu arasındaki ilişkiyi değerlendirmek.
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Sonuç & Katkı:Amaç: Parkinson hastalığında serum D vitamini düzeyleri ile hastalık şiddeti, denge sorunları ve düşme ve düşme korkusu arasındaki ilişkiyi değerlendirmek.
🔬Tür:Research Article
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:fear of falling · neurodegeneration · postural instability

Özet

Amaç: Parkinson hastalığında serum D vitamini düzeyleri ile hastalık şiddeti, denge sorunları ve düşme ve düşme korkusu arasındaki ilişkiyi değerlendirmek.

Abstract

Purpose: To evaluate the relationship between serum vitamin D levels with disease severity, balance problems and fear of falling in Parkinson’s disease. Materials and Methods: This was a retrospective, cross-sectional study. Participants with Parkinson’s disease and healthy controls aged 45-80 years were included in the study. The outcomes of the study were serum 25(OH) vitamin D levels, Hoehn&Yahr Scale, Unified Parkinson’s Disease Rating Scale-III, Berg balance scale, Tinetti test, and International Falls Efficacy Scale scores. Results: Seventy-two participants with Parkinson’s disease and sixty healthy controls were included in the study. The mean 25(OH) vitamin D level was 17.8±8.2 ng/ml in the PD group, while it was 22.2±9.7 ng/ml in the control group. There was a statistically significant difference in terms of 25(OH) vitamin D levels between the groups (p=0.005). The participants in the PD group were divided into two groups according to the HY scale scores (Early-stage group: Stage 1-2; Advanced-Stage group: Stage 3-4). The mean 25(OH) vitamin D level was 18.6±7.8 ng/ml in the early-stage group, it was 16.5±8.8 ng/ml in the advanced-stage group. No statistically significant differences were identified in both groups (p=0.299). There was no correlation between 25(OH) vitamin D levels, HY stages, BBS, TT, FES-I, and UPDRS-III in PD group (p>0.05). Conclusion: Vitamin D levels were lower in PD than that in healthy controls. However, no significant relationship was found between vitamin D levels and disease severity, balance problem, and fear of falling in PD.

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Bu Makaleye Atıf Yap

Korkmaz, M. D. (2022). Parkinson Hastalığında D Vitamini Düzeyinin Hastalık Şiddeti, Denge ve Düşme ile İlişkisi. Ahi Evran Tıp Dergisi, Volume: 6 Issue: 3. https://doi.org/10.46332/aemj.1033448

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