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Dergiler / Hitit Medical Journal / 2024 / Cilt: 6 Sayı: 3

Tiroid Nodül Boyutu Ve Özelliklerinin İnce İğne Aspirasyon Biyopsisinin Doğruluğu Ve Malignite Riski Üzerine Etkisi

The Effect of Thyroid Nodule Size and Characteristics on the Accuracy of Fine-Needle Aspiration Biopsy and the Risk of Malignancy

Mehmet Alperen Avcı(SAMSUN ÜNİVERSİTESİ, TIP FAKÜLTESİ)0000-0003-3911-2686
Can Akgün(SAMSUN UNIVERSITY)0000-0002-8367-0768
Mustafa Gün(SAMSUN UNIVERSITY)0000-0002-2343-0316
Selim Tamam(ANKARA ÜNİVERSİTESİ, TIP FAKÜLTESİ, TIP PR.)0000-0002-2924-1874
Meltem Türk(Ordu Üniversitesi Eğitim Araştırma Hastanesi)0000-0003-3975-331X
Sayfa
321–330
Yayın Tarihi
2024-10-14
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Yaş, cinsiyet, preoperatif ultrason bulguları, preoperatif İİAB sonuçları, ameliyat notları ve postoperatif patoloji bulguları arşivden araştırılmıştır.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Amaç: Ultrasonografi, tiroid nodüllerinin özelliklerinin incelenmesi ve ince iğne aspirasyon biyopsisinin (İİAB) alınması noktasında kolay, avantajlı ve güvenlik-maliyet etkin bir yöntemdir.
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Temel Bulgular & Veri:Bununla beraber, büyük nodüllerde güvenilirliği tartışmalıdır.
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Sonuç & Katkı:Yaş, cinsiyet, preoperatif ultrason bulguları, preoperatif İİAB sonuçları, ameliyat notları ve postoperatif patoloji bulguları arşivden araştırılmıştır.
🔬Tür:Araştırma Makalesi
📍Kapsam:2020 · 522 hasta
⚙️Değişkenler:İnce iğne aspirasyon biyopsisi · tiroid nodülü · ROC analizi

Özet

Amaç: Ultrasonografi, tiroid nodüllerinin özelliklerinin incelenmesi ve ince iğne aspirasyon biyopsisinin (İİAB) alınması noktasında kolay, avantajlı ve güvenlik-maliyet etkin bir yöntemdir. Bununla beraber, büyük nodüllerde güvenilirliği tartışmalıdır. Bu çalışmada amacımız ultrasondaki tiroid nodül boyutu ve özelliklerinin malignite riski üzerine ve ince iğne aspirasyon biyopsisinin doğruluğu üzerine etkisini incelemektir. Gereç ve Yöntem: Çalışmaya, retrospektif olarak 01.01.2020 ile 01.01.2024 tarihleri arasında tiroidektomi operasyonu geçiren 522 hasta dahil edilmiştir. Yaş, cinsiyet, preoperatif ultrason bulguları, preoperatif İİAB sonuçları, ameliyat notları ve postoperatif patoloji bulguları arşivden araştırılmıştır. İstatistiksel analizde Kruskal-Wallis Varyans Analizi, ROC (Receiver Operating Characteristics) eğrisi analizi, Bonferroni Düzeltmeli Mann-Whitney U Testi ve Ki-Kare Testleri kullanılmıştır. Bulgular: Medyan yaş 49,45 olarak bulundu. Preoperatif İİAB ile postoperatif patoloji uyumu incelendiğinde; nodülün X düzlemdeki boyutu için eşik değer 27 mm olarak bulundu (p 27 mm nodüllerde İİAB nin sensivitesinin azaldığı ve false negatif değerinin arttığı görüldü.

Abstract

Objective: Ultrasound evaluation of nodule characteristics and FNAB is a simple, cost-effective method. However, its reliability in large nodules is controversial. This study aims to examine the impact of thyroid nodule size and characteristics on malignancy risk and FNAB accuracy as evaluated by ultrasound. Material and Method: This retrospective study included 522 patients who underwent thyroidectomy between January 1, 2020, and January 1, 2024. The data included the patients’ age, gender, preoperative thyroid ultrasound findings, preoperative FNAB pathology findings, operation notes, and postoperative pathology results colleected from hospital archives. Kruskal-Wallis Variance Analysis, ROC (Receiver Operating Characteristics) curve analysis, Bonferroni Corrected Mann-Whitney U Test, Chi-Square Tests, were used at statistical analysis. Results: The median age was 49.45 years. The threshold value for nodule size in the X plane was 27 mm (p 27 mm.

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Bu Makaleye Atıf Yap

Avcı, M. A., Akgün, C., Gün, M., Tamam, S., Türk, M. (2024). Tiroid Nodül Boyutu Ve Özelliklerinin İnce İğne Aspirasyon Biyopsisinin Doğruluğu Ve Malignite Riski Üzerine Etkisi. Hitit Medical Journal, Cilt: 6 Sayı: 3, 321–330. https://doi.org/10.52827/hititmedj.1501055

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