Dergiler / Journal of Emergency Medicine Case Reports / 2013 / Cilt: 4 Sayı: 4

Dinitro-Ortho-Cresol Maruziyeti Sonrasında Akut Koroner Sendrom Gelişen Ardışık İki Hasta

Two Consecutive Acute Coronary Syndrome Patients after Dinitro-Ortho-Cresol Exposure

Ahmet Oğuz Baktır(Clinic of Cardiology, Kayseri Education and Research Hospital, Kayseri, Turkey)
Hayrettin Sağlam(Clinic of Cardiology, Kayseri Education and Research Hospital, Kayseri, Turkey)
Bahadır Şarlı(Clinic of Cardiology, Kayseri Education and Research Hospital, Kayseri, Turkey)
Hüseyin Arınç(Clinic of Cardiology, Kayseri Education and Research Hospital, Kayseri, Turkey)
Yasemin Doğan(Clinic of Cardiology, Kayseri Education and Research Hospital, Kayseri, Turkey)
Hüseyin Katlandur(Clinic of Cardiology, Kayseri Education and Research Hospital, Kayseri, Turkey)
Sayfa
147–150
Yayın Tarihi
2013-10-01
DOI
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Further examination revealed that toxic exposure led to simultaneous acute coronary syndrome.

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:Nitrophenols are common components of industrial effluents and have been detected in urban and agricultural waste.
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Temel Bulgular & Veri:The main toxic effects of DNOC derivatives are due to an increase in cellular metabolism.
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Sonuç & Katkı:Further examination revealed that toxic exposure led to simultaneous acute coronary syndrome.
🔬Tür:Makale
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:4-Dinitrofenol · akut koroner sendrom · 4-Dinitrofenol toksik maruziyeti

Özet

Nitrophenols are common components of industrial effluents and have been detected in urban and agricultural waste. Dinitro-ortho-cresol (DNOC) can easily enter the body through inhalation, ingestion or the skin. Yellow staining is typical in toxications via skin contact. The main toxic effects of DNOC derivatives are due to an increase in cellular metabolism. It acts directly on metabolism by inducing cellular oxidation and inhibiting phosphorylation, leading to the uncoupling of oxidative phosphorylation. Cardiovascular effects appear to be secondary to cellular anoxia. We report here two consecutive patients admitted to the emergency department with an initial diagnosis of toxic exposure to DNOC. Further examination revealed that toxic exposure led to simultaneous acute coronary syndrome.

Abstract

Nitrophenols are common components of industrial effluents and have been detected in urban and agricultural waste. Dinitroortho-cresol (DNOC) can easily enter the body through inhalation, ingestion or the skin. Yellow staining is typical in toxications via skin contact. The main toxic effects of DNOC derivatives are due to an increase in cellular metabolism. It acts directly on metabolism by inducing cellular oxidation and inhibiting phosphorylation, leading to the uncoupling of oxidative phosphorylation. Cardiovascular effects appear to be secondary to cellular anoxia. We report here two consecutive patients admitted to the emergency department with an initial diagnosis of toxic exposure to DNOC. Further examination revealed that toxic exposure led to simultaneous acute coronary syndrome

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Bu Makaleye Atıf Yap

Baktır, A. O., Sağlam, H., Şarlı, B., Arınç, H., Doğan, Y., Katlandur, H. (2013). Dinitro-Ortho-Cresol Maruziyeti Sonrasında Akut Koroner Sendrom Gelişen Ardışık İki Hasta. Journal of Emergency Medicine Case Reports, Cilt: 4 Sayı: 4, 147–150. https://ajindex.com/articles/1346050

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Kaynakça (11)

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