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Dergiler / Zeynep Kamil Tıp Bülteni / 2026 / Cilt: 51 Sayı: 3

Persistan lökomoid reaksiyon ile seyreden neonatal boğmaca: Olgu sunumu

Neonatal pertussis with persistent leukomoid reaction: a case report

Abdulkadir Bozaykut(İSTANBUL ZEYNEP KAMİL KADIN VE ÇOCUK HASTALIKLARI SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ)
Erdal Sarı(İSTANBUL ZEYNEP KAMİL KADIN VE ÇOCUK HASTALIKLARI SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ)
Rabia Sezer(İSTANBUL ZEYNEP KAMİL KADIN VE ÇOCUK HASTALIKLARI SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ)
Sibel Ergin(İSTANBUL ZEYNEP KAMİL KADIN VE ÇOCUK HASTALIKLARI SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ)
Hatice Güllüelli(Kuzey KIbrıs Türk Cumhuriyeti, Saglık Bakanlığı)
Sayfa
171–173
Yayın Tarihi
2020-09-30
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Bu makalede yenidoğan döneminde boğmaca tanısı alan ve persiste eden lökomoid reaksiyonla seyreden olguyu güncel literatür bilgileri ışığında sunmayı hedefledik.

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:Boğmaca, Bordetella Pertussisin neden olduğu bulaşıcı ve özellikle süt çocuklarında yaşamı tehdit eden bir solunum yolu enfeksiyonu hastalığıdır.
📊
Temel Bulgular & Veri:Ancak aşılamaya başlanmamış bebeklerde mortaliteye sebep olduğundan, son yıllarda boğmaca aşı uygulamalarında koza stratejisi adıyla bilinen yeni bir aşı programı uygulanmaya başlanmıştır.
💡
Sonuç & Katkı:Bu makalede yenidoğan döneminde boğmaca tanısı alan ve persiste eden lökomoid reaksiyonla seyreden olguyu güncel literatür bilgileri ışığında sunmayı hedefledik.
🔬Tür:Literatür & Derleme Çalışması
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:boğmaca · lökomoid reaksiyon · yenidoğan

Özet

Boğmaca, Bordetella Pertussisin neden olduğu bulaşıcı ve özellikle süt çocuklarında yaşamı tehdit eden bir solunum yolu enfeksiyonu hastalığıdır. Her yaşta görülebilir. Ancak aşılamaya başlanmamış bebeklerde mortaliteye sebep olduğundan, son yıllarda boğmaca aşı uygulamalarında koza stratejisi adıyla bilinen yeni bir aşı programı uygulanmaya başlanmıştır. Bu makalede yenidoğan döneminde boğmaca tanısı alan ve persiste eden lökomoid reaksiyonla seyreden olguyu güncel literatür bilgileri ışığında sunmayı hedefledik.

Abstract

Pertussis is a respiratory tract infection caused by Bordetella Pertussis and can be a life threatening disease especially for young infants. It can be seen at any age. Since Pertussis can be mortal for unimmunized infants, a new immunization programme known as Cocooning Strategy is started. Herein, we report a newborn with persistant leukemoid reaction diagnosed as Pertussis and we aimed to discuss the case in the light of current literature.

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Bu Makaleye Atıf Yap

Bozaykut, A., Sarı, E., Sezer, R., Ergin, S., Güllüelli, H. (2020). Persistan lökomoid reaksiyon ile seyreden neonatal boğmaca: Olgu sunumu. Zeynep Kamil Tıp Bülteni, Cilt: 51 Sayı: 3, 171–173. https://ajindex.com/articles/1313400

Kaynakça (19)

  1. Kilgore PE, Salim AM, Zervos MJ et al. Pertussis: microbiology, disease, treatment, and prevention. Clin Microbiol Rev 2016;29:449–86
  2. Greenberg D, Bamberger E, Ben-Shimol S, Gershtein R, Golan D, Srugo I. Pertussis is underdiagnosed in infants hospitalized with lower respiratory tract infection in the pedi¬atric intensive care unit, Med Sci Monit 2007;13:475-80
  3. Wood N, Quinn HE, McIntyre P, Eliot E. Pertussis in infants: preventing deaths and hospitalisations in the very young, Paedtr Child Health 2008;44:161-5. http://dx.doi.org/10.1111/j.1440-1754.2008.01292.x PMid:18377367 4- Long SS, Edwards KM. Bordetella pertussis (pertussis) and other species, “Long SS, Pickering LK, Prober CG (eds). Principles and Practice of Pediatric Infectious Diseases, 4rd ed.” kitabında s.865-73, Churchill Livingstone, Elsevier, Philadelphia (2012)
  4. Long SS, Edwards KM. Bordetalla pertussis and other speci¬es, In: Long SS, Pickering LK, Prober CG, eds. Principles and Practice of Pediatric Infectious Disease; New York: Churchill Livingstone 2003:880-8
  5. Menkes JH, Kinsbourne M. Workshop Pertussis vaccination and neurologic complications. Neuropediatrics 2014.21(4):171-176 7- Von Konig CH, Halperin S, Riffelmann M, Guiso N. Pertussis of adults and infants, Lancet Infect Dis 2002;2:744-50.
  6. Armangil D, Tekinalp G, Yurdakök M, Yalçin E. Maternal pertussis is hazardous for a newborn: a case report. Turk J Pediatr 2010;52(2):206-2010 9- Cevik M, Beyazova U, Aral AL et al. Seroprevalence of IgG antibodies against Bordetella pertussis in healthy individuals aged 4-24 years in Turkey, Clin Microbiol Infect 2008;14(4):388-90
  7. Knuf M, Schmitt HJ, Wolter J, et al. Neonatal vaccination with an acellular pertussis vaccine accelerates the acquisition of pertussis antibodies in infants, J Pediatr 2008;152:655-0
  8. Gilley M, Goldman RD. Protecting infants from pertussis. Can Fam Physician Ceyhan M. Recent improvements in the Turkish Childhood National Immunization Program, Turk J Pediatr 2010;52(6):563-9
  9. Kowaizik F, Barbosa AP, Fernandes VR et al. Prospective multinational study of pertussis infection in hospitalized infants and their household contacts, Pediatr Infect Dis J 2007;26(3):238-42. http://dx.doi.org/10.1097/01.inf.0000256750.07118.ee PMid:17484221 13- Wendelboe AM, Njamkepo E, Bourrillon A et al. Transmission of Bordetella pertussis to young infants, Pediatr Infect Dis J 2007;26(4):293-9. http://dx.doi.org/10.1097/01.inf.0000258699.64164.6d PMid:17414390 14- Ceyhan M. Recent improvements in the Turkish Childhood National Immunization Program, Turk J Pediatr 2010;52(6):563-9. PMid:21428186 15- Blain AE, Lewis M, Banerjee E, Kudish K, Liko J, McGuire S, et al. An assessment of the cocooning strategy for preventing infant pertussis-United States, 2011. Clin Infect Dis 2016;63(Suppl 4):S221-S6
  10. Mattoo S, Cherry JD. Molecular pathogenesis, epidemiology, and clinical manifestations of respiratory infections due to Bordetella pertussis and otherBordetella subspecies. Clin Microbiol Rev. 2005;18(2):326-82 17- Aksakal FN, Cöplü N, Ceyhan MN, Sönmez C, Ozkan S et al. High incidence of pertussis among school children with prolonged cough in Turkey. Tohoku J Exp Med 2007;211:353-8. http://dx.doi.org/10.1620/tjem.211.353 PMID:17409675 1- Kilgore PE, Salim AM, Zervos MJ et al. Pertussis: microbiology, disease, treatment, and prevention. Clin Microbiol Rev 2016;29:449–86
  11. Greenberg D, Bamberger E, Ben-Shimol S, Gershtein R, Golan D, Srugo I. Pertussis is underdiagnosed in infants hospitalized with lower respiratory tract infection in the pedi¬atric intensive care unit, Med Sci Monit 2007;13:475-80
  12. Wood N, Quinn HE, McIntyre P, Eliot E. Pertussis in infants: preventing deaths and hospitalisations in the very young, Paedtr Child Health 2008;44:161-5. http://dx.doi.org/10.1111/j.1440-1754.2008.01292.x PMid:18377367 4- Long SS, Edwards KM. Bordetella pertussis (pertussis) and other species, “Long SS, Pickering LK, Prober CG (eds). Principles and Practice of Pediatric Infectious Diseases, 4rd ed.” kitabında s.865-73, Churchill Livingstone, Elsevier, Philadelphia (2012)
  13. Long SS, Edwards KM. Bordetalla pertussis and other speci¬es, In: Long SS, Pickering LK, Prober CG, eds. Principles and Practice of Pediatric Infectious Disease; New York: Churchill Livingstone 2003:880-8
  14. Menkes JH, Kinsbourne M. Workshop Pertussis vaccination and neurologic complications. Neuropediatrics 2014.21(4):171-176 7- Von Konig CH, Halperin S, Riffelmann M, Guiso N. Pertussis of adults and infants, Lancet Infect Dis 2002;2:744-50.
  15. Armangil D, Tekinalp G, Yurdakök M, Yalçin E. Maternal pertussis is hazardous for a newborn: a case report. Turk J Pediatr 2010;52(2):206-2010 9- Cevik M, Beyazova U, Aral AL et al. Seroprevalence of IgG antibodies against Bordetella pertussis in healthy individuals aged 4-24 years in Turkey, Clin Microbiol Infect 2008;14(4):388-90
  16. Knuf M, Schmitt HJ, Wolter J, et al. Neonatal vaccination with an acellular pertussis vaccine accelerates the acquisition of pertussis antibodies in infants, J Pediatr 2008;152:655-0
  17. Gilley M, Goldman RD. Protecting infants from pertussis. Can Fam Physician Ceyhan M. Recent improvements in the Turkish Childhood National Immunization Program, Turk J Pediatr 2010;52(6):563-9
  18. Kowaizik F, Barbosa AP, Fernandes VR et al. Prospective multinational study of pertussis infection in hospitalized infants and their household contacts, Pediatr Infect Dis J 2007;26(3):238-42. http://dx.doi.org/10.1097/01.inf.0000256750.07118.ee PMid:17484221 13- Wendelboe AM, Njamkepo E, Bourrillon A et al. Transmission of Bordetella pertussis to young infants, Pediatr Infect Dis J 2007;26(4):293-9. http://dx.doi.org/10.1097/01.inf.0000258699.64164.6d PMid:17414390 14- Ceyhan M. Recent improvements in the Turkish Childhood National Immunization Program, Turk J Pediatr 2010;52(6):563-9. PMid:21428186 15- Blain AE, Lewis M, Banerjee E, Kudish K, Liko J, McGuire S, et al. An assessment of the cocooning strategy for preventing infant pertussis-United States, 2011. Clin Infect Dis 2016;63(Suppl 4):S221-S6
  19. Mattoo S, Cherry JD. Molecular pathogenesis, epidemiology, and clinical manifestations of respiratory infections due to Bordetella pertussis and otherBordetella subspecies. Clin Microbiol Rev. 2005;18(2):326-82 17- Aksakal FN, Cöplü N, Ceyhan MN, Sönmez C, Ozkan S et al. High incidence of pertussis among school children with prolonged cough in Turkey. Tohoku J Exp Med 2007;211:353-8. http://dx.doi.org/10.1620/tjem.211.353 PMID:17409675