Tuğcan Korak(KOCAELI UNIVERSITY, SCHOOL OF MEDICINE, DEPARTMENT OF BASIC MEDICAL SCIENCES, MEDICAL DEPARTMENT OF BIOLOGY)0000-0003-4902-4022
Özgür Öztürk(Pharmaceutical Biotechnology, Center for System-based Drug Research, Department of Pharmacy, Ludwig Maximilian University of Munich)0000-0003-2605-4587
Result show that for both protein and DNA dataset, MAFFT may be more useful among three of MSA tool used.
📌 3 Maddede Bu Makale
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Amaç & Hipotez:Multiple sequence alignment (MSA) is used to align three or more sequences of DNA, RNA and protein.
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Temel Bulgular & Veri:In this article three MSA tools; CLUSTALW, SAGA and MAFFT are used for five datasets BALiBASE_R9, DIRMBASE, SABmark and additionally constructed DNABali and ProteinBali for alignment.
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Sonuç & Katkı:Result show that for both protein and DNA dataset, MAFFT may be more useful among three of MSA tool used.
Multiple sequence alignment (MSA) is used to align three or more sequences of DNA, RNA and protein. It is prominent for constructing phylogenetic trees and evolutionary relationships between sequences with regard to similarities and dissimilarities. Variety of multiple sequence alignment tools are available online, each having different methods and parameters to align sequences. In this article three MSA tools; CLUSTALW, SAGA and MAFFT are used for five datasets BALiBASE_R9, DIRMBASE, SABmark and additionally constructed DNABali and ProteinBali for alignment. Result show that for both protein and DNA dataset, MAFFT may be more useful among three of MSA tool used.
Aşır, F., Korak, T., Öztürk, Ö. (2021). THREE MSA TOOLS ANALYSIS in DNA and PROTEIN DATASETS. Middle East Journal of Science, Volume: 7 Issue: 2. https://doi.org/10.51477/mejs.983750
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