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Dergiler / Hacettepe Journal of Biology and Chemistry / 2026 / Volume: 46 Issue: 3

Synthesis, Structural Calculations and Molecular Docking Studies of a Novel Uracil Derived Organic Molecule

Gamze Koz(BURSA TECHNICAL UNIVERSITY, FACULTY OF NATURAL SCIENCES, ARCHITECTURE AND ENGINEERING, DEPARTMENT OF CHEMISTRY)
Sayfa
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Yayın Tarihi
2018-09-01
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

The physicochemical properties of the molecule such as frontier molecule orbitals and chemical reactivity parameters were also investigated. 

📌 3 Maddede Bu Makale

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Amaç & Hipotez:A novel uracil derived compound, (E)-5-((3-chloro-2-hydroxybenzylidene)amino) pyrimidine-2,4(1H,3H)- dione, was synthesized and characterized using spectroscopic techniques.
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Temel Bulgular & Veri:The interaction of the molecule with DNA was explored using computational methods which revealed that the molecule could act as a groove binder.
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Sonuç & Katkı:The physicochemical properties of the molecule such as frontier molecule orbitals and chemical reactivity parameters were also investigated. 
🔬Tür:Research Article
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Uracil · Schiff base · DNA binding

Abstract

A novel uracil derived compound, (E)-5-((3-chloro-2-hydroxybenzylidene)amino) pyrimidine-2,4(1H,3H)- dione, was synthesized and characterized using spectroscopic techniques. The interaction of the molecule with DNA was explored using computational methods which revealed that the molecule could act as a groove binder. The physicochemical properties of the molecule such as frontier molecule orbitals and chemical reactivity parameters were also investigated. 

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Bu Makaleye Atıf Yap

Koz, G. (2018). Synthesis, Structural Calculations and Molecular Docking Studies of a Novel Uracil Derived Organic Molecule. Hacettepe Journal of Biology and Chemistry, Volume: 46 Issue: 3. https://ajindex.com/articles/1270652

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Kaynakça (16)

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