Özet
85
Abstract
At the present days, developments in the pharmaceutical industry ans technological progression continues to increase. The Pharmaceutical products which are sold a lot, are marketed under different names by pharmaceutical companies. Thus, containing the same active ingredient in the same amount is increasing rapidly the number of similar preparations on the market. The similar products which are same active ingredient in the same amount must be equivalent to each other to be pharmaceutically bioequivalent. Drugs should be effective, safe, affordable and acceptable cost. The amount of drugs which reach from application area to target area, is important. This means is bioavailability. The bioavailability is the most important factor on the medication treatment applications. Whether obtain the therapeutic response of systemically active drugs is determined by bioavailability studies. Therefore, the health authorities which permit to production and sale of drugs, want to prove generic drugs to be bioequivalent to the original drug. To get better quality, cheaper and safer drugs will be possible with bioavailability and bioequivalence studies