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Dergiler / Dicle Tıp Dergisi / 2026 / Cilt: 47 Sayı: 3

The Most Important Factors in Prognosis Of Obstetric Patients with Disseminated Intravascular Coagulation: A Tertiary Center Study

Abdulkadir Turgut(İSTANBUL MEDENİYET ÜNİVERSİTESİ)
Nurullah Peker(DICLE UNIVERSITY)
Elif Ağaçayak(DICLE UNIVERSITY)
Gamze Akın Evsen(DICLE UNIVERSITY)
Edip Aydın(UNIVERSITY OF HEALTH SCIENCES, DİYARBAKIR GAZİ YAŞARGİL HEALTH RESEARCH CENTER, DEPARTMENT OF INTERNAL MEDICINE, DEPARTMENT OF INFECTIOUS DISEASES)
Mehmet Sait İçen(DICLE UNIVERSITY)
Talip Karaçor(ADIYAMAN UNIVERSITY)
Fatih Mehmet Fındık(DICLE UNIVERSITY)
Feyzi Çelik(DICLE UNIVERSITY)
Emre Dirican(DICLE UNIVERSITY)
Talip Gül(DICLE UNIVERSITY)
Sayfa
517–524
Yayın Tarihi
2020-09-25
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

INR and ALT is the most important laboratory parameter in DIC and also can affect mortality.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Objective: The aim of this study was to investigate the underlying causes of obstetrical disseminated intravascular coagulation (DIC) and to evaluate the laboratory and clinical signs affecting DIC-related morbidity and mortality in women diagnosed with obstetrical DIC in a tertiary referral hospital.
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Temel Bulgular & Veri:Method: The retrospective study included women with DIC who either had a delivery at Dicle University Medical School Gynecology and Obstetrics Department or were referred to this department prior to delivery between May 2006 and May 2016.
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Sonuç & Katkı:INR and ALT is the most important laboratory parameter in DIC and also can affect mortality.
🔬Tür:Araştırma Makalesi
📍Kapsam:2006 Verileri
⚙️Değişkenler:disseminated intravascular coagulation (DIC) · mortality · obstetrics

Özet

Objective: The aim of this study was to investigate the underlying causes of obstetrical disseminated intravascular coagulation (DIC) and to evaluate the laboratory and clinical signs affecting DIC-related morbidity and mortality in women diagnosed with obstetrical DIC in a tertiary referral hospital. Method: The retrospective study included women with DIC who either had a delivery at Dicle University Medical School Gynecology and Obstetrics Department or were referred to this department prior to delivery between May 2006 and May 2016. DIC scoring was performed using the DIC scoring system developed by the International Society of Thrombosis and Hemostasis (ISTH) in 2001. Results: A total of 82 women with obstetrical DIC were included in the study. The incidence of obstetrical DIC in our department was 0.41%. Overall mortality rate was 24% and mortality occurred in 8% of the patients with a DIC score of ≤5 and in 12% of the patients with a score of >5 (p=0.043). Multiple logistic regression analysis indicated that increased INR (International Normalized Ratio) and ALT (Alanin Aminotransferaz) levels led to a significant increase in DIC-related mortality [OR: 1.803 (CI: 1.027-3.167), OR: 1.003 (CI: 1.001-1.005), respectively]. Conclusions: Obstetrical DIC may result in high mortality and morbidity. DIC scoring can be useful for predicting the prognosis and DIC-related mortality. INR and ALT is the most important laboratory parameter in DIC and also can affect mortality.

Abstract

Objective: The aim of this study was to investigate the underlying causes of obstetrical disseminated intravascular coagulation (DIC) and to evaluate the laboratory and clinical signs affecting DIC-related morbidity and mortality in women diagnosed with obstetrical DIC in a tertiary referral hospital. Method: The retrospective study included women with DIC who either had a delivery at Dicle University Medical School Gynecology and Obstetrics Department or were referred to this department prior to delivery between May 2006 and May 2016. DIC scoring was performed using the DIC scoring system developed by the International Society of Thrombosis and Hemostasis (ISTH) in 2001. Results: A total of 82 women with obstetrical DIC were included in the study. The incidence of obstetrical DIC in our department was 0.41%. Overall mortality rate was 24% and mortality occurred in 8% of the patients with a DIC score of ≤5 and in 12% of the patients with a score of >5 (p=0.043). Multiple logistic regression analysis indicated that increased INR (International Normalized Ratio) and ALT (Alanin Aminotransferaz) levels led to a significant increase in DIC-related mortality [OR: 1.803 (CI: 1.027-3.167), OR: 1.003 (CI: 1.001-1.005), respectively]. Conclusions: Obstetrical DIC may result in high mortality and morbidity. DIC scoring can be useful for predicting the prognosis and DIC-related mortality. INR and ALT is the most important laboratory parameter in DIC and also can affect mortality.

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Bu Makaleye Atıf Yap

Turgut, A., Peker, N., Ağaçayak, E., Evsen, G. A., Aydın, E., İçen, M. S., Karaçor, T., Fındık, F. M., Çelik, F., Dirican, E., Gül, T. (2020). The Most Important Factors in Prognosis Of Obstetric Patients with Disseminated Intravascular Coagulation: A Tertiary Center Study. Dicle Tıp Dergisi, Cilt: 47 Sayı: 3, 517–524. https://doi.org/10.5798/dicletip.799622

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