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Dergiler / Journal of Surgery and Medicine / 2021 / Cilt: 5 - Sayı: 9

Effects of antenatal magnesium sulfate use for neuroprotection on cardiorespiratory complications during the early neonatal period in preterm infants

Nuran ÜSTÜN
Meryem HOCAOĞLU
Abdulkadir TURGUT
Fahri OVALI
Sayfa
843–847
Yayın Tarihi
2021-09-01
DOI
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Results: Mothers in the MgSO4 group were more likely to have preeclampsia and antenatal steroid treatment, while their infants were younger in gestation and weighed less (P

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Amaç & Hipotez:Background/Aim: Antenatal magnesium sulfate (MgSO4) treatment is widely used for fetal neuroprotection in women at risk of preterm delivery.
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Temel Bulgular & Veri:Possible adverse effects of MgSO4 include respiratory depression and delay in closure of ductus arteriosus by antagonism of calcium channels.
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Sonuç & Katkı:Results: Mothers in the MgSO4 group were more likely to have preeclampsia and antenatal steroid treatment, while their infants were younger in gestation and weighed less (P
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Antenatal magnesium sulfate · Neonatal resuscitation · Patent ductus arterisus

Abstract

Background/Aim: Antenatal magnesium sulfate (MgSO4) treatment is widely used for fetal neuroprotection in women at risk of preterm delivery. Possible adverse effects of MgSO4 include respiratory depression and delay in closure of ductus arteriosus by antagonism of calcium channels. The aim of this study was to investigate the effects of antenatal MgSO4 exposure on cardiorespiratory complications during the early neonatal period in premature infants. Methods: A retrospective cohort study was performed on 340 preterm infants born between 23 and 32 weeks of gestational age. Patients were divided into two groups according to antenatal MgSO4 exposure: The MgSO4 group (n=186) and the no-MgSO4 group (n=154). Outcomes were acute cardiorespiratory events (intubation at birth, respiratory support, and hypotension in first day of life), and hemodynamically significant patent ductus arteriosus (HsPDA). Results: Mothers in the MgSO4 group were more likely to have preeclampsia and antenatal steroid treatment, while their infants were younger in gestation and weighed less (P

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Bu Makaleye Atıf Yap

ÜSTÜN, N., HOCAOĞLU, M., TURGUT, A., OVALI, F. (2021). Effects of antenatal magnesium sulfate use for neuroprotection on cardiorespiratory complications during the early neonatal period in preterm infants. Journal of Surgery and Medicine, Cilt: 5 - Sayı: 9, 843–847. https://ajindex.com/articles/779830

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Kaynakça (8)

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