Dergiler / Turkish Journal of Medical Sciences / 2018 / Cilt: 48 - Sayı: 2

Risk factor assessment for breast cancer in North Cyprus: a comprehensive case-control study of Turkish Cypriot women

Sayfa
293–304
Yayın Tarihi
2018-04-01
DOI
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Conclusion: Our results demonstrate the presence of classical as well as several additional BC risks. e ndings will be of great bene t in establishing adequate evidence-based awareness and preventative measures in the North Cyprus population.

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Amaç & Hipotez:Background/aim: This case-control study aims to assess the strength of associations between reproductive, lifestyle, sociodemographic, and dietary factors as well as other potential breast cancer risks and breast cancer (BC) in a North Cyprus population.
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Temel Bulgular & Veri:Materials and methods: The study includes 408 BC patients and 412 age-matched controls recruited from Near East Hospital and Dr.
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Sonuç & Katkı:Conclusion: Our results demonstrate the presence of classical as well as several additional BC risks. e ndings will be of great bene t in establishing adequate evidence-based awareness and preventative measures in the North Cyprus population.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Breast cancer · risk factors · odds ratios

Abstract

Background/aim: This case-control study aims to assess the strength of associations between reproductive, lifestyle, sociodemographic, and dietary factors as well as other potential breast cancer risks and breast cancer (BC) in a North Cyprus population. Materials and methods: The study includes 408 BC patients and 412 age-matched controls recruited from Near East Hospital and Dr. Burhan Nalbantoglu State Hospital in North Cyprus. Information regarding clinical and epidemiological characteristics was collected through a standardized interview. Age-adjusted odds ratios (ORs) and 95% con dence intervals (CIs) were calculated by logistic regression before and a er adjusting for the potential confounders. Results: In addition to various recognized BC risk factors, strong associations with BC were reported from women with fertility drugs used for >6 cycles (OR = 3.305, 95% CI 1.850?5.906, P < 0.001), depression (OR = 2.10, 95% CI 1.33?3.30, P < 0.001), exposure to radiation (OR = 1.74, 95% CI 1.02?2.98, P = 0.041), and excess consumption of oil (OR = 2.703, 95% CI 1.62?4.48, P < 0.001) and sugar (OR = 3.42, 95% CI 1.39?8.40, P = 0.007). Parental consanguinity (OR = 0.16, 96% CI 0.09?0.30, P < 0.001) and daily water intake of 1?2 L (OR = 0.36, 95% CI 0.19?0.66, P < 0.001) were strong protective factors. Conclusion: Our results demonstrate the presence of classical as well as several additional BC risks. e ndings will be of great bene t in establishing adequate evidence-based awareness and preventative measures in the North Cyprus population.

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Bu Makaleye Atıf Yap

PERVAIZ, R., TOSUN, Ö., BESIM, H., SERAKINCI, N. (2018). Risk factor assessment for breast cancer in North Cyprus: a comprehensive case-control study of Turkish Cypriot women. Turkish Journal of Medical Sciences, Cilt: 48 - Sayı: 2, 293–304. https://ajindex.com/articles/113638

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