Dergiler / Turkish Journal of Medical Sciences / 2018 / Cilt: 48 - Sayı: 2

Risk factor assessment for breast cancer in North Cyprus: a comprehensive case-control study of Turkish Cypriot women

Sayfa
293–304
Yayın Tarihi
2022-11-05
DOI
—
🏛️Bu makalenin bibliyografik verileri ve tam metin bağlantısı DergiPark üzerinden sağlanmıştır.
DergiPark Kaydı ↗
✨

Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

The findings will be of great benefitin establishing adequate evidence-based awareness and preventative measures in the North Cyprus population.

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:Background/aim: This case-control study aims to assess the strength of associations between reproductive, lifestyle, sociodemographic,and dietary factors as well as other potential breast cancer risks and breast cancer (BC) in a North Cyprus population.Materials and methods: The study includes 408 BC patients and 412 age-matched controls recruited from Near East Hospital and Dr.Burhan Nalbantoglu State Hospital in North Cyprus.
📊
Temel Bulgular & Veri:Age-adjusted odds ratios (ORs) and 95% confidence intervals (CIs) were calculated by logisticregression before and after adjusting for the potential confounders.Results: In addition to various recognized BC risk factors, strong associations with BC were reported from women with fertility drugsused for >6 cycles (OR = 3.305, 95% CI 1.850–5.906, P < 0.001), depression (OR = 2.10, 95% CI 1.33–3.30, P < 0.001), exposure toradiation (OR = 1.74, 95% CI 1.02–2.98, P = 0.041), and excess consumption of oil (OR = 2.703, 95% CI 1.62–4.48, P < 0.001) and sugar(OR = 3.42, 95% CI 1.39–8.40, P = 0.007).
💡
Sonuç & Katkı:The findings will be of great benefitin establishing adequate evidence-based awareness and preventative measures in the North Cyprus population.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

Background/aim: This case-control study aims to assess the strength of associations between reproductive, lifestyle, sociodemographic,and dietary factors as well as other potential breast cancer risks and breast cancer (BC) in a North Cyprus population.Materials and methods: The study includes 408 BC patients and 412 age-matched controls recruited from Near East Hospital and Dr.Burhan Nalbantoglu State Hospital in North Cyprus. Information regarding clinical and epidemiological characteristics was collectedthrough a standardized interview. Age-adjusted odds ratios (ORs) and 95% confidence intervals (CIs) were calculated by logisticregression before and after adjusting for the potential confounders.Results: In addition to various recognized BC risk factors, strong associations with BC were reported from women with fertility drugsused for >6 cycles (OR = 3.305, 95% CI 1.850–5.906, P < 0.001), depression (OR = 2.10, 95% CI 1.33–3.30, P < 0.001), exposure toradiation (OR = 1.74, 95% CI 1.02–2.98, P = 0.041), and excess consumption of oil (OR = 2.703, 95% CI 1.62–4.48, P < 0.001) and sugar(OR = 3.42, 95% CI 1.39–8.40, P = 0.007). Parental consanguinity (OR = 0.16, 96% CI 0.09–0.30, P < 0.001) and daily water intake of1–2 L (OR = 0.36, 95% CI 0.19–0.66, P < 0.001) were strong protective factors.Conclusion: Our results demonstrate the presence of classical as well as several additional BC risks. The findings will be of great benefitin establishing adequate evidence-based awareness and preventative measures in the North Cyprus population.

🔖

Bu Makaleye Atıf Yap

TOSUN, Ö., BESIM, H., SERAKINCI, N., PERVAIZ, R. (2022). Risk factor assessment for breast cancer in North Cyprus: a comprehensive case-control study of Turkish Cypriot women. Turkish Journal of Medical Sciences, Cilt: 48 - Sayı: 2, 293–304. https://ajindex.com/articles/610309

📄 Tam Metin PDF Okuyucu

📄

PDF görüntüleyici hazırlanıyor...

Kaynakça (11)

  1. Siegel RL, Miller KD, Jemal A. Cancer statistics, 2015. CA Cancer J Clin 2015; 65: 15-29.
  2. Braunwald E. Fauci AS, Kasper DL, Hauser SL, Longo DL, Jameson JL. Harrison’s Principles of Internal Medicine. New York, NY, USA: McGraw-Hill; 2005.
  3. Kelsey JL, Horn-Ross PL. Breast cancer: magnitude of the problem and descriptive epidemiology. Epidemiol Rev 1993; 15: 7-16.
  4. Mucci LA, Kaprio J, Harris J, Czene K, Kraft P, Scheike T, Graff RE, Holst K, Möller S, Unger RH et al. Heritability and familial risk of cancer: an update from the Nordic Twin Registry of Cancer (NorTwinCan). In: The American Society of Human Genetics 63rd Annual Meeting; Boston, MA, USA; 2013.
  5. Pharoah PP, Day NE, Duffy S, Easton DF, Ponder BAJ. Family history and the risk of breast cancer: a systematic review and meta-analysis. Int J Cancer 1997; 71: 800-809.
  6. Pervaiz R, Tosun Ö, Besim H, Serakinci N. Dietary factors modify post-menopausal breast cancer risk: a case-control study from Turkish Cypriot population. Biomedical Research and Therapy 2017; 4: 1171-1184.
  7. Demetriou CA, Hadjisavvas A, Loizidou MA, Loucaides G, Neophytou I, Sieri S, Kakouri E, Middleton N, Vineis P, Kyriacou K. Dietary pattern and breast cancer risk in GreekCypriot women: a case-control study. BMC Cancer 2012; 12: 113. Hung MC, Ekwueme DU, Rim SH, White A. Racial/ethnicity disparities in invasive breast cancer among younger and older women: an analysis using multiple measures of population health. Cancer Epidemiol 2016; 45: 112-118.
  8. Parkin DM, Bray F, Ferlay J, Pisani P. Global cancer statistics, 2002. CA Cancer J Clin 2005; 55: 74-108.
  9. Hinçal E, Taneri B, Taneri U, Djamgoz MB. Cancer incidence in North Cyprus (1990-2004) relative to European rates. Asian Pac J Cancer Prev 2008; 9: 725-732.
  10. Pervaiz R, Tulay P, Faisal F, Serakinci N. Incidence of cancer in the Turkish Republic of Northern Cyprus. Turk J Med Sci 2017; 47: 523-530.
  11. Krainer M, Silva-Arrieta S, FitzGerald MG, Shimada A, Ishioka C, Kanamaru R, MacDonald DJ, Unsal H, Finkelstein DM, Bowcock A et al. Differential contributions of BRCA1 and BRCA2 to early-onset breast cancer. N Engl J Med 1997; 336: 1416-1422. Anglian Breast Cancer Study Group. Prevalence and penetrance of BRCA1 and BRCA2 mutations in a population-based series of breast cancer cases. Br J Cancer 2000; 83: 1301. Pervaiz R, Faisal F, Serakinci N. Practice of consanguinity and attitudes towards risk in the Pashtun population of Khyber Pakhtunkhwa, Pakistan. J Biosoc Sci 2017 (in press). Martinez-Gonzalez