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Dergiler / Experimed / 2022 / Volume: 12 Issue: 3

Cerrahpaşa Medical Faculty Hospital HIV-1/-2 Serological Test Data: 2019-2022 Retrospective Evaluation

Harika Öykü Dinç(BEZM-İ ÂLEM VAKIF ÜNİVERSİTESİ)0000-0003-3628-7392
Elif Keskin(İSTANBUL ÜNİVERSİTESİ - CERRAHPAŞA, CERRAHPAŞA TIP FAKÜLTESİ)0000-0001-8264-0703
Banu Tufan Koçak(SAĞLIK BİLİMLERİ ÜNİVERSİTESİ, İSTANBUL ERENKÖY RUH SAĞLIĞI VE SİNİR HASTALIKLARI SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ)0000-0002-6435-0785
Bekir Kocazeybek(İSTANBUL ÜNİVERSİTESİ-CERRAHPAŞA, CERRAHPAŞA TIP FAKÜLTESİ, TEMEL TIP BİLİMLERİ BÖLÜMÜ, TIBBİ MİKROBİYOLOJİ ANABİLİM DALI)0000-0003-1072-3846
Sayfa
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Yayın Tarihi
2022-12-31
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

HIV prevalence in Istanbul, being a cosmopolitan city that receives immigrants, should be monitored in the future.

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Amaç & Hipotez:Objective: The aim of this study was to retrospectively discuss the human immunodeficiency virus (HIV) scanning and verification test results and demographics of patients who were admitted to the Istanbul University Cerrahpaşa Medical Faculty’s Medical Microbiology Laboratory Center Serology/ELISA division with suspected HIV infection or pre-operative serologic screening.
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Temel Bulgular & Veri:Materials and Methods: HIV-1/-2 antibody +P24 antigen (HIV-1/-2 Ab/Ag) was studied routinely using the chemiluminescent microparticle immunoassay (CMIA) method with the same method also being used as the second repeat test.
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Sonuç & Katkı:HIV prevalence in Istanbul, being a cosmopolitan city that receives immigrants, should be monitored in the future.
🔬Tür:Research Article
📍Kapsam:2019-2022 Verileri
⚙️Değişkenler:HIV-1/2 · CMIA · LIA

Abstract

Objective: The aim of this study was to retrospectively discuss the human immunodeficiency virus (HIV) scanning and verification test results and demographics of patients who were admitted to the Istanbul University Cerrahpaşa Medical Faculty’s Medical Microbiology Laboratory Center Serology/ELISA division with suspected HIV infection or pre-operative serologic screening. In addition, the study aimed to compare HIV seroprevalence with data from the center’s previous period. Materials and Methods: HIV-1/-2 antibody +P24 antigen (HIV-1/-2 Ab/Ag) was studied routinely using the chemiluminescent microparticle immunoassay (CMIA) method with the same method also being used as the second repeat test. The sera verifications of patients who showed repeated reactivity after the HIV Ab/Ag test were studied using the line immunoassay (LIA) method. Results: The study retrospectively studied 156,542 cases between 2019-2022, of which 237 (0.17%) showed repeated anti-HIV-1/-2 reactivity. From the repeated reactivity serum samples, LIA testing was performed to confirm the remaining 181 serum samples after excluding the previously confirmed samples, with 175 (96.6%) coming back positive. All these samples showed sgp120 and gp41 band positivity, thus confirming HIV1 positivity. Conclusion: These retrospective data from one center regarding HIV seroprevalence for the 2019-2022 period are in line with other national studies. However, due to the COVID-19 pandemic, HIV prevalence during this period may have been higher than detected. HIV prevalence in Istanbul, being a cosmopolitan city that receives immigrants, should be monitored in the future.

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Bu Makaleye Atıf Yap

Dinç, H. Ö., Keskin, E., Koçak, B. T., Kocazeybek, B. (2022). Cerrahpaşa Medical Faculty Hospital HIV-1/-2 Serological Test Data: 2019-2022 Retrospective Evaluation. Experimed, Volume: 12 Issue: 3. https://doi.org/10.26650/experimed.1191760

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