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Dergiler / Experimed / 2026 / Volume: 14 Issue: 2

The Effects of Panax ginseng on Serum Oxidative Stress Following Bisphenol A Exposure

Najiullah Fazalyar(MARMARA UNIVERSITY, INSTITUTE OF HEALTH SCIENCES, BIOCHEMISTRY (MEDICINE) (DR))0009-0009-0725-8702
Seren Ede Pazarbaşı(MARMARA UNIVERSITY, INSTITUTE OF HEALTH SCIENCES, BIOCHEMISTRY (MEDICINE) (DR))0000-0002-3195-4064
Doğancan Dörücü(MARMARA UNIVERSITY, SCHOOL OF MEDICINE, DEPARTMENT OF SURGICAL MEDICAL SCIENCES, THE DEPARTMENT OF UROLOGY)0000-0002-9714-3336
Göksel Şener(Fenerbahçe University, Faculty of Pharmacy, Department of Pharmacology)0000-0001-7444-6193
Tuğba Tunalı Akbay(MARMARA UNIVERSITY, FACULTY OF DENTISTRY, DEPARTMENT OF BASIC SCIENCES)0000-0002-2091-9298
Sayfa
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Yayın Tarihi
2024-08-26
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Conclusion: BPA was seen to cause an increase in oxidative parameters and PxG administration to restore the oxidative stress that was generated after BPA exposure, suggesting that this may help to prevent the adverse effects caused by BPA exposure.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Objective: Bisphenol A (BPA) is a toxic compound that causes oxidative stress by disrupting antioxidant enzymes and promoting tissue lipid peroxidation.
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Temel Bulgular & Veri:Materials and Methods: Wistar Albino rats (250-300 g) were divided into control, control + PxG, BPA, and BPA + PxG groups. 50 mg/kg BPA and 100 mg/g PxG were given for six weeks.
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Sonuç & Katkı:Conclusion: BPA was seen to cause an increase in oxidative parameters and PxG administration to restore the oxidative stress that was generated after BPA exposure, suggesting that this may help to prevent the adverse effects caused by BPA exposure.
🔬Tür:Research Article
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Bisphenol A · Panax ginseng · oxidative stress

Abstract

Objective: Bisphenol A (BPA) is a toxic compound that causes oxidative stress by disrupting antioxidant enzymes and promoting tissue lipid peroxidation. This study aimed to examine the impacts of BPA on serum oxidative stress in rats and to detect the antioxidant feature of Panax ginseng (PxG) in reducing BPA-induced oxidative stress. Materials and Methods: Wistar Albino rats (250-300 g) were divided into control, control + PxG, BPA, and BPA + PxG groups. 50 mg/kg BPA and 100 mg/g PxG were given for six weeks. Serum total antioxidant and oxidant status, lipid peroxidation, and glutathione levels were determined. Results: BPA administration increased total oxidant status and lipid peroxidation, while PxG administration to the BPA group decreased these parameters. PxG also increased total antioxidant status and glutathione levels compared to the BPA group. Conclusion: BPA was seen to cause an increase in oxidative parameters and PxG administration to restore the oxidative stress that was generated after BPA exposure, suggesting that this may help to prevent the adverse effects caused by BPA exposure.

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Bu Makaleye Atıf Yap

Fazalyar, N., Pazarbaşı, S. E., Dörücü, D., Şener, G., Akbay, T. T. (2024). The Effects of Panax ginseng on Serum Oxidative Stress Following Bisphenol A Exposure. Experimed, Volume: 14 Issue: 2. https://doi.org/10.26650/experimed.1443398

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