Dergiler / Bozok Journal of Science / 2023 / Cilt: 1 Sayı: 2

Effective Use of Oxalyl Chloride Compound in Synthesis of Oxalohydrazide and Parabanic Acid Derivatives

Sayfa
81–86
Yayın Tarihi
2023-11-30
DOI
—
🏛️Bu makalenin bibliyografik verileri ve tam metin bağlantısı DergiPark üzerinden sağlanmıştır.
DergiPark Kaydı ↗
✨

Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Compounds (4 and 5) characterized by elemental analysis, 1H, and 13C-NMR spectra are conformable by structure.

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:Oxalyl chloride, (COCl)2, as an easily available chemical, is one of the organic reagents that are highly applicable in chemical reactions.
📊
Temel Bulgular & Veri:In this context, we report the reactions of oxalyl chloride (1) with cyanoacetyl hydrazide (2) and N,N'-diarylcarbazone (3) for the first time here.
💡
Sonuç & Katkı:Compounds (4 and 5) characterized by elemental analysis, 1H, and 13C-NMR spectra are conformable by structure.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Oxalyl Chloride · Carbazone · Cyanoacetyl hydrazide

Abstract

Oxalyl chloride, (COCl)2, as an easily available chemical, is one of the organic reagents that are highly applicable in chemical reactions. It is used as the starting material of various chemical transformations such as ring closure in organic reactions, ring opening of epoxides, chlorination, and formylation. In this context, we report the reactions of oxalyl chloride (1) with cyanoacetyl hydrazide (2) and N,N'-diarylcarbazone (3) for the first time here. Compounds (4 and 5) characterized by elemental analysis, 1H, and 13C-NMR spectra are conformable by structure.

🔖

Bu Makaleye Atıf Yap

KIBRIZ, İ. E., SAÇMACI, M., YILDIRIM, İ. (2023). Effective Use of Oxalyl Chloride Compound in Synthesis of Oxalohydrazide and Parabanic Acid Derivatives. Bozok Journal of Science, Cilt: 1 Sayı: 2, 81–86. https://ajindex.com/articles/1020368

📄 Tam Metin PDF Okuyucu

📄

PDF görüntüleyici hazırlanıyor...

Kaynakça (3)

  1. R. Salmon and I. V. Efremov, “in Encyclopedia of Reagents for Organic Synthesis,” John Wiley & Sons, Weinheim, 2001. A. Fauconnier, “The Action of Phosphorus Pentachloride on Diethyl Oxalate,” Comptes Rendus Acad. Sci., vol. 114, pp. 122–123, 1892. W. Li, Y. Asada, and T. Yoshikawa, “Antimicrobial Flavonoids from Glycyrrhiza Glabra Hairy Root Cultures,” Planta Med., vol. 64, pp. 746–747, Dec. 1998, doi:10.1055/s-2006-957571.
  2. S. Jang, S. Jeung, K. Kim, H. Kim, H. Yu, R. Park, H. Kim, and Y. You, “Tanshinone IIA from Salvia miltiorrhiza Inhibits Inducible Nitric Oxide Synthase Expression and Production of TNF-α, IL-1β and IL-6 in Activated RAW 264.7 Cells,” Planta Med., vol. 69, pp. 1057–1059, Nov. 2003, doi:10.1055/s-2003-45157. G. B. M. Bettòlo, C. G. Casinovi, and C. Galeffi, “A New Class of Quinones: Sesquiterpenoid Quinones of Mansonia altissima Chev,” Tetrahedron Lett., vol. 52, pp. 4857–4864, 1965, doi: 10.1016/S0040-4039(01)89048-1. C. C. Shen, “Phenolic Constituents of the Roots of Sophora flavescens,” J. Nat. Prod., vol. 69, pp. 1237–1240, Aug. 2006, doi:10.1021/np060189d. M. Knaack, P. Emig, J. W. Bats, M. Kiesel, A. Müller, and E. Günther, “Synthesis and Characterization of the Biologically Active 2-[1-(4-chlorobenzyl)-1H-indol-3-yl] -2-oxo-N-pyridin-4-yl acetamide,” Eur. J. Org. Chem., vol. 2001, pp. 3843–3847, Sep. 2001, doi:10.1002/1099-0690(200110)2001:20 3.0.CO;2-P. M. D. Armistead, W. M. Harding, J. O. Saunders, and S. J. Boger, “Biologically Active Acylated Amino Acid Derivatives,” United States Patent. US 5723459, 1998.
  3. B. R. Bacon, S. C. Gordon, E. Lawitz, P. Marcellin, J. M. Vierling, S. Zeuzem. F. Poordad, Z. D. Goodman, H. L. Sings, N. Boparai, M. Burroughs, C. A. Brass, J. K. Albrecht, and R. Esteban, “Boceprevir for Previously Treated Chronic HCV Genotype 1 Infection,” N. Engl. J. Med., vol. 364, pp. 1207–1217, Mar. 2011, doi:10.1056/NEJMoa1009482. T. F. Hartley, P. L. Lieberman, E. O. Meltzer, J. N. Noyes, D. S. Pearlman, and D. G. Tinkelman, “Efficacy and Tolerance of Fluocortin Butyl Administered Twice Daily in Adult Patients with Perennial Rhinitis,” J. Allergy Clin. Immunol., vol. 75, pp. 501–507, Apr. 1985, doi:10.1016/s0091-6749(85)80024-5.