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Journals / European Journal of General Medicine / 2007 / Cilt: 4 Sayı: 4

Investigation Of Anti-Inflammatory Activity Of Bergamot Oil

Mehmet Karaca
Hanefi Özbek
Aydın Him
Mehmet Tütüncü
Hasan Altan Akkan
Veysel Kaplanoğlu
Pages
176–179
Publication Date
2007-12-01
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Results: It was found that reduction in the inflammation was 95.70% with indomethacin, 27.56% with 0.025 mL/kg BO, 30.77% with 0.05 mL/kg BO and 63.39% with 0.10 mL/kg BO.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: Essential oil of Bergamot (BO) was investigated for anti-inflammatory activity using carrageenan-induced rat paw oedema test.
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Key Findings & Data:Methods: For the anti-inflammatory activity measurement six different groups were established and BO was administered in three different doses: 0.025, 0.05 and 0.10 mL/kg.
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Conclusion & Impact:Results: It was found that reduction in the inflammation was 95.70% with indomethacin, 27.56% with 0.025 mL/kg BO, 30.77% with 0.05 mL/kg BO and 63.39% with 0.10 mL/kg BO.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Citrus aurantium subsp. bergamia · Bergamot oil · anti-inflammatory activity

Abstract

Aim: Essential oil of Bergamot (BO) was investigated for anti-inflammatory activity using carrageenan-induced rat paw oedema test. Methods: For the anti-inflammatory activity measurement six different groups were established and BO was administered in three different doses: 0.025, 0.05 and 0.10 mL/kg. Indomethacin was used as a reference agent. Results: It was found that reduction in the inflammation was 95.70% with indomethacin, 27.56% with 0.025 mL/kg BO, 30.77% with 0.05 mL/kg BO and 63.39% with 0.10 mL/kg BO. Indomethacin showed the strongest anti-inflammatory activity among the drugs used. The strongest anti-inflammatory activity of BO was seen with 0.10 mL/kg dosage. Median effective dose (ED50) value of BO was found to be 0.079 mL/kg. Conclusion: The results showed that BO posseses promising anti-inflammatory effect

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Cite This Article

Karaca, M., Özbek, H., Him, A., Tütüncü, M., Akkan, H. A., Kaplanoğlu, V. (2007). Investigation Of Anti-Inflammatory Activity Of Bergamot Oil. European Journal of General Medicine, Cilt: 4 Sayı: 4, 176–179. https://ajindex.com/articles/987896

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