Selective Antimicrobial Properties of W-Ge Nanocomposite Thin Films

Based on the antibacterial activity test, it was concluded that although all the films had antimicrobial efficiency against gram-negative and gram-positive bacteria, they were more effective against gram-positive bacteria.

📌 3 Key Takeaways

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Objective & Hypothesis:The antimicrobial properties of W-Ge nanocomposite thin films as a function of Ge concentration were investigated within the scope of this study.

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Key Findings & Data:The films were deposited on an AZ61Mg substrate using a magnetron sputter source with a co-deposition technique.

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Conclusion & Impact:Based on the antibacterial activity test, it was concluded that although all the films had antimicrobial efficiency against gram-negative and gram-positive bacteria, they were more effective against gram-positive bacteria.

🔬Design:Research Article

📍Scope:Comprehensive Sample

⚙️Variables:nanocomposite thin film · tungsten · germanium

Abstract

The antimicrobial properties of W-Ge nanocomposite thin films as a function of Ge concentration were investigated within the scope of this study. The films were deposited on an AZ61Mg substrate using a magnetron sputter source with a co-deposition technique. Structural analyses showed that all coatings had a composite crystal structure. Additionally, the morphological investigation indicated that films had goosefoot-type structures at low Ge concentrations (5% and 10%), while Ge-rich films (40% and 60%) had cauliflower-type structures. The 20% Ge concentration coating had both structures. Regarding the surface morphology, the root mean square roughness of the surface reached its maximum value at a Ge concentration of 60% while the surface roughness and wettability of all the films showed an opposite trend. The antimicrobial activity of the W-Ge nanocomposite films against gram-negative (Salmonella typhimurium NRRLE 4413, Escherichia coli ATCC 25922) and gram-positive (Staphylococcus aureus 6538 P., Bacillus subtilis IM 622) bacteria was investigated via disc diffusion antibiotic sensitivity assay. Based on the antibacterial activity test, it was concluded that although all the films had antimicrobial efficiency against gram-negative and gram-positive bacteria, they were more effective against gram-positive bacteria. Moreover, with the increased surface roughness of the films, the number of grain boundaries, which cause an increase in the intensity of the oxide phases of the metals, increases, resulting in better antibacterial activity.

Keywords

nanocomposite thin film tungsten germanium antibacterial efficiency surface roughness

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Cite This Article

ATASOY, S., KURUL, Y., AKTAŞ, S., SARCAN, F., KURT, M. Ş., AYNA, A., DARENDELİOĞLU, E., EROL, A. (2023). Selective Antimicrobial Properties of W-Ge Nanocomposite Thin Films. Physics and Astronomy Reports, Cilt: 1 Sayı: 1, 38–48. https://ajindex.com/articles/977711

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References (1)

Akhavan O., Ghaderi E., 2010, ACS Nano, 4, 5731 google scholar Arslan M. E., Kurt M. Ş., Aslan N., Kadi A., Öner S., Çobanoğlu Ş., Yazici A., 2022, Journal of Biomedical Materials Research Part B: Applied Biomaterials, 110, 1667 google scholar Bian D., et al., 2017, Acta Biomaterialia, 64, 421 google scholar Cassie A. B. D., Baxter S., 1944, Trans. Faraday Soc., 40, 546 google scholar Chuang K.-T., Abdullah H., Leu S.-J., Cheng K.-B., Kuo D.-H., Chen H.-C., Chien J.-H., Hu W.-T., 2017, Journal of Photochemistry and Photobiology A: Chemistry, 337, 151 google scholar Eaton P., Fernandes J. C., Pereira E., Pintado M. E., Xavier Malcata F., 2008, Ultramicroscopy, 108, 1128 google scholar Foadi F., Vaez Allaei S. M., Palasantzas G., Mohammadizadeh M. R., 2019a, Phys. Rev. E, 100, 022804 google scholar Foadi F., ten Brink G. H., Mohammadizadeh M. R., Palasantzas G., 2019b, Journal of Applied Physics, 125 google scholar Helmersson U., Lattemann M., Bohlmark J., Ehiasarian A. P., Gud-mundsson J. T., 2006, Thin Solid Films, 513, 1 google scholar Jena G., Anandkumar B., Vanithakumari S., George R., Philip J., Amarendra G., 2020, Progress in Organic Coatings, 139, 105444 google scholar Kaplan B. J., Parish W. W., Andrus G. M., Simpson J. S. A., Field C. J., 2004, The Journal of Alternative and Complementary Medicine, 10, 337 google scholar Khalid A. Q., AlJohny B. O., Wainwright M., 2014, African Journal of Microbiology Research, 8, 1080 google scholar Kurt M. Ş., Arslan M. E., Yazici A., Mudu İ., Arslan E., 2021, Journal of Materials Science: Materials in Medicine, 32, 6 google scholar Kuruoğlu F., 2022, Microfluidics and Nanofluidics, 26, 72 google scholar Law K.-Y., 2014, The Journal of Physical Chemistry Letters, 5, 686 google scholar Lück B. E., Mann H., Melzer H., Dunemann L., Begerow J., 1999, Nephrology Dialysis Transplantation, 14, 2464 google scholar Martin P. M., 2009, Handbook of Deposition Technologies for Films and Coatings: Science, Applications and Technology. William Andrew google scholar Menazea A., Awwad N. S., 2020, Journal of Materials Research and Technology, 9, 9434 google scholar Nagata N., Yoneyama T., Yanagida K., Ushio K., Yanagihara S., Mat-subara O., Eishi Y., 1985, The Journal of Toxicological Sciences, 10, 333 google scholar Okada K., Okagawa K., Kawakami K., et al. 1989, Clinical Nephrol-ogy, 31, 219 google scholar Park S.-M., Ikegami T., Ebihara K., Shin P.-K., 2006, Applied Surface Science, 253, 1522 google scholar Roy D., Halder N.,