AI Summary & Key Takeaways
AI InsightIt was found that seropositivity significantly higher in female patients (p<0.10).
📌 3 Key Takeaways
Abstract
Objective: Although brucellosis is the most common zoonosis in the world, it remains an infectious disease that has not received sufficient attention. This study’s aim was to retrospectively examine the results of the Rose Bengal and Brucellacapt tests in serum samples from patients with a prior diagnosis of brucellosis sent to our laboratory in our province, a highly endemic area for brucellosis. Materials and Methods: Between June 2019 and June 2021, 7827 serum samples sent to the public health laboratory with a provisional diagnosis of brucellosis were evaluated. The Rose Bengal and Brucellacapt test (Vircell, Spain) was used diagnose infection. Samples with antibody titer ≥1/160 were considered positive. Results: Of the 7827 samples included in the study, 354 (4.6%) of the total 7677 serum samples tested were RBT positive, 118 (3.1%) of the 3776 samples tested were BCAP positive, and 118 (3.3%) of the 3626 samples tested were both RBT and BCAP positive. It was found that seropositivity significantly higher in female patients (p<0.10). RBT and BCAP test positivity was most frequently observed in the 25-34 year age group. Considering brucellosis cases in terms of seasonal changes; 10.7% of cases were found in spring, 52.4% in summer, 20.9% in fall and 16% in winter. Conclusion: In suspected cases, RBT is still considered the ideal detection method because it is easy to use, inexpensive, sensitive, and provides rapid results. It was concluded that the BCAP test is suitable for diagnosis due to its ability to detect blocker and high titer antibodies.