Journals / Acta Medica Nicomedia / 2023 / Cilt: 6 Sayı: 2

Inhibitory Effect of Cell Phones Against Human Breast Cancer and Myeloid Leukemia Cells Proliferation in Culture Media

Kültür Ortamında İnsan Meme Kanseri ve Miyeloid Lösemi Hücrelerinin Proliferasyonuna Karşı Cep Telefonlarının İnhibitör Etkisi

Pages
192–197
Publication Date
2023-06-30
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In MTT test, it was found out that two types of cell proliferation was inclined to slow down with the effect of cell phone.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: There is current news that emerges regarding the relationship between the magnetic effects of cell phones and some types of cancer.
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Key Findings & Data:Methods: In the study, breast cancer MCF-7 and leukemia K562 cell lines were used as the source of cancer cell.
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Conclusion & Impact:In MTT test, it was found out that two types of cell proliferation was inclined to slow down with the effect of cell phone.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Kanser Hücreleri · Manyetik alan · Cep telefonu

Abstract

Objective: There is current news that emerges regarding the relationship between the magnetic effects of cell phones and some types of cancer. In spite of the studies carried out, the level of evidence of this news is low, and also the relationship between the magnetic effects of cell phones and other types of cancer is not certain except for brain cancer. In this study, it is aimed at examining the effects of magnetic field of cell phones on the samples of breast cancer human myeloid leukemia cell growth. Methods: In the study, breast cancer MCF-7 and leukemia K562 cell lines were used as the source of cancer cell. During the six-day cell culture, cancer cells were subjected to the effects of cell phone by using a telephone call program (Automated outbound call software). The system made 6 calls for 1 minute for each call once in 144 minutes from fixed line. The number of cultured cells and proliferation capacities of the two types of tumor cells in the control and experimental groups were assessed. Results: The number of cancer cells, which were subjected to the effects of cell phone as a result of the culture of tumor cells, was found lower when compared with control group (7500000 ± 100000 vs 6625000 ± 225000 for MCF-7; 15412500 ± 112500 vs 13700000 ± 250000 for K562; P < 0.05 for both). In MTT test, it was found out that two types of cell proliferation was inclined to slow down with the effect of cell phone. Conclusion: The results can be translated that cell phone may inhibit neoplastic transformation, and this observation may promote to initiate a new clinical studies both for healthy people and for patients with cancer.

Özet

Amaç: Cep telefonlarının manyetik etkileri ile bazı kanser türleri arasındaki ilişkiye dair güncel haberler bulunmaktadır. Yapılan araştırmalara rağmen bunların kanıt düzeyi düşüktür. Ayrıca cep telefonlarının manyetik etkilerinin beyin kanseri dışında diğer kanser türleri ile ilişkisi kesin değildir. Bu çalışmada, insan meme kanseri ve miyeloid lösemi hücre örneklerinin proliferasyonu üzerinde cep telefonlarının manyetik alanının etkilerinin incelenmesi amaçlanmıştır. Yöntemler: Çalışmada kanser hücresi kaynağı olarak meme kanseri MCF-7 ve lösemi K562 hücre dizileri kullanıldı. Altı günlük hücre kültürü sırasında kanser hücreleri, bir telefon arama programı (otomatik giden arama yazılımı) kullanılarak cep telefonunun etkilerine maruz bırakıldı. Sistem sabit hattan 144 dakikada bir her aramada 1’er dakika süreyle 6 arama yaptı. Kontrol ve deney gruplarındaki iki tip tümör hücresinin kültürlenen hücre sayısı ve çoğalma kapasiteleri değerlendirildi. Bulgular: Tümör hücrelerinin kültürü sonucunda cep telefonu etkisine maruz kalan kanser hücrelerinin sayısı kontrol grubuna göre daha düşük bulundu (7500000 ± 100000 vs 6625000 ± 225000 MCF-7 için; 15412500 ± K562 için 112500 vs 13700000 ± 250000; her ikisi için P < 0.05). MTT testinde iki tip hücre çoğalmasının cep telefonunun etkisiyle yavaşlamaya meyilli olduğu tespit edildi. Sonuç: Sonuçlar, cep telefonunun neoplastik dönüşümü engelleyebileceği şeklinde tercüme edilebilir ve bu gözlem hem sağlıklı insanlar hem de kanserli hastalar için yeni bir klinik çalışma başlatmayı teşvik edebilir.

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Cite This Article

BOĞA, B., AKBULUT, M., MAYTALMAN, E., KOZANOĞLU, İ. (2023). Inhibitory Effect of Cell Phones Against Human Breast Cancer and Myeloid Leukemia Cells Proliferation in Culture Media. Acta Medica Nicomedia, Cilt: 6 Sayı: 2, 192–197. https://ajindex.com/articles/948348

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