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Journals / Phoenix Medical Journal / 2021 / Cilt: 3 Sayı: 3

The Clinical Importance of Hematological Parameters In Patients with Pulmonary Thromboembolism Diagnosed in The Emergency Department

Acil Serviste Pulmoner Tromboemboli Tanısı Konulan Hastalarda Hematolojik Parametrelerin Klinik Önemi

Resmiye Nur Okudan(Gebze Fatıh State Hospıtal, Department of Emergency Medicine, Kocaeli /Turkey)0000-0003-4187-7928
Fevzi Yılmaz(ANTALYA EĞİTİM VE ARAŞTIRMA HASTANESİ, ACİL TIP)0000-0002-3675-7457
Serkan Yüksel(Kahta State Hospıtal, Department of Radiology, Adıyaman /Turkey)0000-0002-6165-6455
Mehmet Karadaş(Baskent University, Alanya Research and Teaching Center, Department of Emergency Medicine, Alanya, Turkey)0000-0002-4719-2535
Adeviyye Karaca(Health Sciences University, Antalya Education and Research Hospital; Department of Emergency Medicine, Antalya /Turkey)0000-0002-5338-1826
Gizem Ayaz(Health Sciences University, Antalya Education and Research Hospital; Department of Emergency Medicine, Antalya /Turkey)0000-0002-4476-7989
Ömer Faruk Karakoyun(Muğla Training and Research Hospital; Department of Emergency Medicine, Muğla /Turkey)0000-0002-4476-7989
Pages
123–129
Publication Date
2021-11-01
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Analysis of the hematological parameters between the APE subgroups showed that D-Dimer, leukocyte (WBC), neutrophil, lymphocyte, neutrophil to lymphocyte ratio (NLR), and troponin levels were significantly higher in the massive APE group than the sub-massive and non-massive APE groups.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Acute pulmonary embolism (APE) is a highly fatal acute clinical condition.
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Key Findings & Data:Patients with an RV/LV ratio greater than 0,9 on Computed tomography (CT) and hypotension were grouped as massive APE; patients with stable hemodynamics and an RV/LV ratio greater than 0,9 on CT were defined as submissive APE; and patients with stable hemodynamics and an RV/LV ratio smaller than 0,9 on CT were defined as non-massive APE.
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Conclusion & Impact:Conclusion: Analysis of the hematological parameters between the APE subgroups showed that D-Dimer, leukocyte (WBC), neutrophil, lymphocyte, neutrophil to lymphocyte ratio (NLR), and troponin levels were significantly higher in the massive APE group than the sub-massive and non-massive APE groups.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Akut pulmoner emboli · Hematolojik Parametreler · Acil Servis.

Abstract

Objective: Acute pulmonary embolism (APE) is a highly fatal acute clinical condition. Herein, we aimed to determine the role of blood parameters in the diagnosis and prognostication of APE. Material and Method: This study was conducted retrospectively on patients who had been admitted to our hospital’s emergency department (ED) and diagnosed with APE. Patients with an RV/LV ratio greater than 0,9 on Computed tomography (CT) and hypotension were grouped as massive APE; patients with stable hemodynamics and an RV/LV ratio greater than 0,9 on CT were defined as submissive APE; and patients with stable hemodynamics and an RV/LV ratio smaller than 0,9 on CT were defined as non-massive APE. Results: This study enrolled a total of 200 patients, 82 of which were male (41%) and 118 were female (59%). APE group had a significantly greater D-dimer level than the control group (3.559,5±8.611.3 ng/ml vs 266.6±266.6 ng/ml) (p<0,001). Troponin I levels significantly greater in the patient group than control group (53.3±90 vs 332.9±32,9) (p= 0.013). Conclusion: Analysis of the hematological parameters between the APE subgroups showed that D-Dimer, leukocyte (WBC), neutrophil, lymphocyte, neutrophil to lymphocyte ratio (NLR), and troponin levels were significantly higher in the massive APE group than the sub-massive and non-massive APE groups.

Özet

ÖZET Amaç: Akut pulmoner emboli (APE), oldukça ölümcül bir akut klinik durumdur. Burada APE’nin tanı ve prognozunda kan parametrelerinin rolünü belirlemeyi amaçladık. Gereç ve Yöntem: Bu çalışma hastanemizin Acil Servisine (AS) başvuran ve APE tanısı konulan hastalar üzerinde geriye dönük olarak yapıldı. Bilgisayarlı tomografi (BT)’de RV / LV oranı 0.9’dan büyük ve hipotansiyonu olan hastalar masif APE; BT’de RV / LV oranı 0,9’dan büyük olan ve stabil hemodinamik sahip hastalar submasif APE; BT’de RV / LV oranı 0,9’dan küçük ve hemodinamisi stabil olan hastalar masif olmayan APE olarak sınıflandırıldı. Bulgular: Bu çalışmaya 82’si erkek (%41), 118’i kadın (%59) olmak üzere toplam 200 hasta alındı. Hasta ve kontrol grubunun yaş ortalaması sırasıyla 65,2 ± 17,1 ve 60,5 ± 60,5 yıldı. APE grubu, kontrol grubuna göre anlamlı olarak daha yüksek D-dimer düzeyine sahipti (3559,5±8611,3 ng/ml’ye karşı 266,6±266,6 ng/ml) (p<0,001). Troponin I düzeyleri hasta grubunda anlamlı olarak daha yüksekti (53,3±90’a karşı 332,9±32,9) (p= 0,013). Sonuç: Hematolojik parametrelerin APE alt grupları arasındaki analizi, masif APE grubunda D-Dimer, lökosit (WBC), nötrofil, lenfosit, nötrofil / lenfosit oranı (NLR) ve troponin düzeylerinin sub-masif APE ve masif olmayan APE grubuna göre anlamlı olarak daha yüksek olduğunu gösterdi.

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Cite This Article

Okudan, R. N., Yılmaz, F., Yüksel, S., Karadaş, M., Karaca, A., Ayaz, G., Karakoyun, Ö. F. (2021). The Clinical Importance of Hematological Parameters In Patients with Pulmonary Thromboembolism Diagnosed in The Emergency Department. Phoenix Medical Journal, Cilt: 3 Sayı: 3, 123–129. https://doi.org/10.38175/phnx.989396

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