AI Summary & Key Takeaways
AI InsightIn conclusion, it was observed that the acute phase response and oxidative stress were increased in cows that were under intensive stress and obstetric intervention during dystocia.
📌 3 Key Takeaways
Abstract
Pregnancy, which includes many different mechanisms and is a physiological process, may cause an increase or decrease in the levels of acute phase proteins (APP) due to the acute phase response occurring in the organism, since it affects many mechanisms in animals. Acute phase proteins can be used not only to determine the diagnosis and prognosis of the inflammatory process, but also to identify non-inflammatory conditions such as pregnancy, childbirth, metabolic diseases, and stress. The aim of this study was to determine some APP and oxidative stress levels in normal parturition and in cows with dystocia. For this purpose, 15 normal parturition and 15 cows with dystocia (Simental breed) were used in the study. Some of the blood collected from animals' Vena jugularis after birth (between 3-48 hours) was placed in tubes with anticoagulant, and the remainder in tubes without anticoagulation. As a result of the analysis, it was determined that haptoglobin, ceruloplasmine and malondialdehyde increased in cows with dystocia while albumin and reduced glutathione concentrations decreased. In conclusion, it was observed that the acute phase response and oxidative stress were increased in cows that were under intensive stress and obstetric intervention during dystocia. It was concluded that antioxidant applications against oxidative stress may be beneficial in addition to the applications to prevent infection in cows, especially in dystocia.
Özet
Çok farklı mekanizmalar içeren ve fizyolojik bir süreç olan gebelik, hayvanlarda birçok mekanizmayı etkilemesi nedeniyle, organizmada oluşan akut faz yanıta bağlı olarak akut faz proteinleri (AFP) düzeylerinde artış veya azalışa neden olabilmektedir. Akut faz proteinleri sadece yangısal sürecin teşhis ve prognozunu belirlemek amacıyla değil, aynı zamanda gebelik, doğum, metabolik hastalıklar ve stres gibi yangısal olmayan durumların belirlenmesinde de kullanılabilmektedir. Bu nedenle çalışmanın amacı normal ve güç doğum yapan ineklerde bazı AFP’lerin ve oksidatif stres düzeyinin belirlenmesidir. Çalışmada, 15 adet normal ve 15 adet ise güç doğum yapan Simental ırkı inek kullanıldı. Hayvanların Vena jugularis’inden doğum sonrası (3-48 saat arasında) alınan kanın bir miktarı antikoagulanlı tüplere, kalan kısmı ise antikoagulansız tüplere konuldu. Yapılan analizler sonucunda güç doğum yapan ineklerde haptoglobin, seruloplazmin ve malondialdehidin arttığı, albümin ve redükte