Journals / Middle Black Sea Journal of Health Science / 2023 / Cilt: 9 Sayı: 1

The Relationship Between Coronary Slow Flow and Myocardial Ischaemia Evaluated with Timi Frame Count and Myocardial Perfusion Scintigraphy

Pages
1–12
Publication Date
2023-02-28
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Although at a weak level, a linear correlation was found between the Cx TIMI frame count and the sTPD-Cx and the sscore-Cx values

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Coronary slow flow (CSF) is known as a form or early stage of common atherosclerotic disease.
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Key Findings & Data:Methods: A total of 168 patients who applied with the complaint of angina pectoris and underwent SPECT as a non-invasive test followed by coronary angiography were included in this retrospective study. 9 patient was excluded from the study for various reasons.
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Conclusion & Impact:Although at a weak level, a linear correlation was found between the Cx TIMI frame count and the sTPD-Cx and the sscore-Cx values
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Coronary slow flow · TIMI frame count · myocardial perfusion scintigraphy

Abstract

Objective: Coronary slow flow (CSF) is known as a form or early stage of common atherosclerotic disease. Myocardial perfusion scintigraphy (MPS) is a valuable technique in the diagnosis of coronary artery disease and prediction of prognosis. The aim of this study was to investigate the relationship between the myocardial defect score and ischaemia in patients with CSF. Methods: A total of 168 patients who applied with the complaint of angina pectoris and underwent SPECT as a non-invasive test followed by coronary angiography were included in this retrospective study. 9 patient was excluded from the study for various reasons. The study population comprised determined with CSF and no obstructive stricture in the coronary arteries and with normal flow. The mean age of the patients was 56±12 years. The scores obtained from Quantitative Perfusion SPECT (QPS) and Quantitative Gated SPECT (QGS) software were used in the myocardial perfusion evaluation. The TIMI frame counts were compared with the myocardial defect and ischaemia scores. The TIMI frame count method was used in the determination of CSF. Results: In patients with slow flow in the circumflex (Cx) coronary artery, the stress total perfusion defect Cx (sTPD-Cx) was found to be 0.1 (range, 0.0-1.3), and in those with normal flow, it was 0.0 (range, 0.0-0.28) (p=0.002). The stress score Cx (sscore-Cx) was found to be 1.0 (range, 0.0-3.0) in patients with slow flow and 0.0 (range, 0.0-2.0) in those with normal flow (p=0.031). A linear correlation was determined between the Cx TIMI frame count and the sTPD-Cx and sscore-Cx values (r=0.207, p=0.009; r=0.159, p=0.045). No relationship was found between slow flow and the defect and ischemia scores in other myocardial regions. Conclusion: In patients with slow flow in the Cx coronary artery, the sTPD-Cx and the sscore-Cx values were found to be significantly high. Although at a weak level, a linear correlation was found between the Cx TIMI frame count and the sTPD-Cx and the sscore-Cx values

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Cite This Article

YILMAZTEKİN, M. Z., KAYAPİNAR, O., AKTÜRE, G., COŞKUN, G., AŞIK, M., AFŞİN, H. (2023). The Relationship Between Coronary Slow Flow and Myocardial Ischaemia Evaluated with Timi Frame Count and Myocardial Perfusion Scintigraphy. Middle Black Sea Journal of Health Science, Cilt: 9 Sayı: 1, 1–12. https://ajindex.com/articles/910310

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References (11)

  1. Kemp HG, Vokoanas PS, Cohn PF, Gorlin R. The anginal syndrome associated with normal coronary arteriograms. Report of a six-year experience. Am J Med 1973; 54: 735-42
  2. Tambe AA, Demany MA, Zimmerman HA, Mascarenhas E. Angina pectoris and slowflow velocity of dye in coronary arteries-A new angiografic finding. Am Heart J 1972; 84 66-71
  3. Sezgin AT, Sigirci M, Barutcu I. Vascular endothelial function in patients with slow coronary flow. Coron Artery Dis 2003; 14: 155-161. Mosseri M, Yorom R, Gotsman MS, Hasin Y. Histologic evidence for small vessel coronary artery disease in patients with angina pectoris and patent large coronay arteries. Circulation 1986; 7: 964-972
  4. Mangieri M, Machiarelli G, Ciavolella M, Barilla F, Avella A, Martinotti A, et al. Slow coronary flow: Clinical and histopatological features in patients with otherwise normal epicardial coronary arteries. Cathet Cardiovasc Diag 1996; 37: 375-381
  5. Kurtoğlu N, Akcay A, Dindar I. Usefulness of oral dypridamole therapy for angiographic slow coronary artery flow. Am J Cardiol 2001; 87(Suppl 8A): 777-779
  6. Pekdemir H, Polat G, Cin VG, Camsari A, Cicek D, Akkus MN, Doven O, Katircibasi MT, Muslu N. Elevated plasma endothelin-1 levels in coronary sinus during rapid rate atrial pacing in patients with coronary slow flow. İnt J Cardiol 2004;97(1):35-41
  7. Pekdemir H, Cin VG, Cicek D, Camsari A, Akkus MN, Doven O, Parmaksiz HT. Slow coronary flow may be a sign of diffuse atherosclerosis. Contribution of FFR and IVUS. Acta Cardiol 2004; 59(2):127-33 8. Pekdemir H, Cin VG, Cicek D, Camsari A, Akkus MN, Doven O, Parmaksiz HT. Slow coronary flow may be a sign of diffuse atherosclerosis. Contribution of FFR and IVUS. Acta Cardiol 2004; 59(2):127-33
  8. Cin VG, Pekdemir H, Camsari A, Cicek D, Akkus MN, Parmaksiz HT, Katircibasi MT, Doven O. Diffuse İntimal Thickening of Coronary Arteries in Slow Coronary Flow. Japan Heart J. 2003; 44: 907,919 10. Goel PK, Gupta SK, Agarwal A, Kapoor A. Slow coronary flow: A distinct angiographic subgroup in Syndrome X. Angiology. 2001; 52(8): 507-14
  9. The Thrombolysis in Myocardial Infarction (TIMI) trial. Phase I findings. TIMI Study Group. N Engl J Med. 1985 Apr 4;312(14):932-6
  10. Gibson CM, Cannon CP, Daley WL, Dodge JT, Jr., Alexander B, Jr., Marble SJ, et al. TIMI frame count: a quantitative method of assessing coronary artery flow. Circulation. 1996 Mar 1;93(5):879-88
  11. Slomka PJ, Berman DS, Germano G, Quantification of myocardial perfusion. In: