Journals / Kafkas Journal of Medical Sciences / 2015 / Yıl: 2015 Sayı: 2

Platelet Count and Mean Platelet Volume in the Prediction of Colorectal Cancer in Patients Presented with Emergency Ileus

Trombosit Sayısı ve Ortalama Trombosit Hacminin Acil İleusu Olan Hastalarda Kolorektal Kanseri Öngörmesi

Pages
65–69
Publication Date
2015-07-01
DOI
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CONCLUSION: Higher platelet count and mean platelet volume values may predict colorectal cancer in cases with acute abdomen diagnosed with ileus.

📌 3 Key Takeaways

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Objective & Hypothesis:AIM: We aimed to investigate whether there is a role of platelet number and mean platelet volume in the prediction of colorectal cancer in emergency ileus patients.
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Key Findings & Data:METHODS: In this retrospective study, ileus cases undergone urgent laparotomy were split into two groups as: Group 1 (G1) included colorectal cancer patients diagnosed with intra operative fi ndings and Group 2 (G2) included patients without cancer.
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Conclusion & Impact:CONCLUSION: Higher platelet count and mean platelet volume values may predict colorectal cancer in cases with acute abdomen diagnosed with ileus.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Kolorektal kanser · ileus · ortalama trombosit hacmi

Abstract

AIM: We aimed to investigate whether there is a role of platelet number and mean platelet volume in the prediction of colorectal cancer in emergency ileus patients. METHODS: In this retrospective study, ileus cases undergone urgent laparotomy were split into two groups as: Group 1 (G1) included colorectal cancer patients diagnosed with intra operative fi ndings and Group 2 (G2) included patients without cancer. Platelet count and mean platelet volume values were compared between two groups. RESULTS: Distribution of female/male patients between groups were homogeneus (p: 0.724), however mean age of colorectal cancer cases were higher (p: 0.008). Mean platelet volume values and platelet count were higher in cases with colorectal cancer (p: 0.040 and p: 0.004, respectively). Mean platelet volume had 63.3 % sensitivity and 56.5 % specifi ty, and platelet count had 63.3 % sensitivity and 62.9 % specifi ty in prediction of colorectal cancer amongst emergency ileus cases. CONCLUSION: Higher platelet count and mean platelet volume values may predict colorectal cancer in cases with acute abdomen diagnosed with ileus.

Özet

AMAÇ: Trombosit sayısı ve ortalama trombosit hacminin acil ileus endikasyonu ile ameliyat edilen hastalarda kolorektal kanseri öngörmede rolü olup olmadığını araștırmayı amaçladık. YÖNTEM: Bu retrospektif çalıșmada, ileus tanısıyla acil laparotomi yapılan hastalar iki gruba ayrıldı: Grup 1 (G1) intraoperatif bulgulara göre kolorektal kanser tanısı alanlar ve Grup 2 (G2) kanseri olmayan hastalar. Trombosit sayısı ve ortalama trombosit hacmi iki grup arasında karșılaștırıldı. BULGULAR: Gruplar arası kadın/erkek dağılımı homojendi (p: 0,724), ancak kolorektal kanser saptanan hastalardaki yaș ortalaması daha yüksek idi (p: 0,008). Kolorektal kanser saptanan hastalardaki ortalama trombosit hacmi ve trombosit sayısı anlamlı dü- zeyde yüksekti (sırasıyla, p: 0,040 ve p: 0,004). Kolorektal kanseri öngörmede; ortalama trombosit hacmi %63,3 sensitivite, %56,5 spesifite ve trombosit sayısı %63,3 sensitivitesi ve %62,9 spesifiteye sahipti. SONUÇ: Akut abdomeni olan ve ileus tanısı konulan olgularda, daha yüksek trombosit sayısı ve ortalama trombosit hacmi kolorektal kanseri öngörebilir

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Cite This Article

Anuk, T., Çığşar, G., Yıldırım, A. C., Özgehan, G., Gökce, E., Güzel, H., İrem, B., Kama, A., Gülkan, S., Gürsoy, G. (2015). Platelet Count and Mean Platelet Volume in the Prediction of Colorectal Cancer in Patients Presented with Emergency Ileus. Kafkas Journal of Medical Sciences, Yıl: 2015 Sayı: 2, 65–69. https://ajindex.com/articles/892255

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