Journals / Interdisciplinary Medical Journal / 2016 / Cilt: 7 - Sayı: 25

Comparison the Different Opioids with Propofol for Sedoanalgesia in D&C Operation

D&C operasyonlarında sedoanaljezi için propofol ile kullanılan farklı opioidlerin karşılaştırılması

Pages
10–18
Publication Date
2016-04-12
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Also compared with other groups in GroupPR were provided earlier recovery and the number of thosewho need additional propofol was less than (p<0.05).Conclusion: In our study propofol plus remifentanil ensuredearlier recovery and higher surgeon satisfaction whencompared with fentanyl and pethidine.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: Dilatation and curettage (D&C) is a common day-careprocedure in obstetrics and gynecology.
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Key Findings & Data:In this study weaimed to investigate the effect of different opioids withpropofolon recovery and its effects on hemodynamicparameters combination for sedoanalgesia.Materials and Methods: This study was conducted in 105patients who undergoing D & C operations.
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Conclusion & Impact:Also compared with other groups in GroupPR were provided earlier recovery and the number of thosewho need additional propofol was less than (p<0.05).Conclusion: In our study propofol plus remifentanil ensuredearlier recovery and higher surgeon satisfaction whencompared with fentanyl and pethidine.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Fentanil · küretaj · propofol

Abstract

Aim: Dilatation and curettage (D&C) is a common day-careprocedure in obstetrics and gynecology. In this study weaimed to investigate the effect of different opioids withpropofolon recovery and its effects on hemodynamicparameters combination for sedoanalgesia.Materials and Methods: This study was conducted in 105patients who undergoing D & C operations. Anesthesiainduction were ensured with 1.5 mg/kg propofol+1 mcg/kgremifentanil in Group PR, 1.5 mg/kg propofol+1 mcg/kgfentanyl in Group PF and 1.5 mg/kg propofol+1 mg/kgpethidine in Group PP. Duration of anesthesia, ModifiedAldrete Score (MAS), hemodynamic parameters (afterinduction 5., 10., 15. minutes and postoperative 0, 5, and 10minutes) and the number of patients receiving additionalpropofol were recorded. Also surgeon satisfaction, sideeffects and complications were recorded at the end ofsurgery.Results: Heart rate was significantly lower in Group PR thanother groups (p<0.05). Group PR and Group PP showedsimilar effects on heart rate postoperative period but inGroup PR more was suppressed than Group PF (p<0.05).There was no difference in the postoperative period whilemean arterial pressure (MAP) was significantly lower inGroup PR than Group PF in intraoperative period (p<0.05).There was no difference between the groups at other times,while MAP was significantly lower in Group PP than GroupPF in postoperative 0. minute (p<0.05). According to thegroup PP surgeon satisfaction were better in both Group PRand Group PF. Also compared with other groups in GroupPR were provided earlier recovery and the number of thosewho need additional propofol was less than (p<0.05).Conclusion: In our study propofol plus remifentanil ensuredearlier recovery and higher surgeon satisfaction whencompared with fentanyl and pethidine.

Özet

Amaç: Dilatasyon ve uterus küretajı (D&C) yaygın bir günübirlik obstetrik ve jinekolojik prosedürdür. Biz bu çalışmada sedoanaljezi için propofol ile kullanılan farklı opioidlerin derlenme ve hemodinamik parametreler üzerine etkilerini araştırmayı amaçladıkGereç ve Yöntem: Bu çalışma D&C operasyonu yapılacak hastalarda gerçekleştirildi. Anestezi indüksiyonu Grup-PR’de 1.5 mg/kg propofol+1 mcg/kg remifentanil ile, Grup-PF’de 1.5 mg/kg propofol+1 mcg/kg fentanil ile ve Grup-PP’de 1.5 mg/kg propofol+1 mg/kg petidin ile sağlandı. Anestezi süresi, Modifiye Aldret Skoru (MAS), hemodinamik parametreler (indüksiyon sonrası 5.,10., 15. dakikalar ve postoperatif 0., 5., ve 10.dakikalarda) ve ek propofolverilen hastaların sayısı kaydedildi. Ayrıca operasyon sonunda cerrah memnuniyeti, yan etki ve komplikasyonlar kayıt edildi.Bulgular:Çalışmamızda kalp hızı indüksiyon sonrası Grup PR’de diğer gruplardan daha düşüktü(p<0.05). Postoperatif dönemde Grup PR, kalp hızı üzerine Grup PP ile benzer etki gösterdi fakat Grup PR’de Grup PF’den daha çok baskılandı(p<0.05). Ortalama arter basıncı (OAB) Grup PR’de Grup PF’ye göre intraoperatif dönemde daha düşük iken postoperatif dönemde fark yoktu (p<0.05).OAB açısından Grup PF ile Grup PP karşılaştırıldığında postoperatif 0. dakikada Grup PP’de daha düşük olduğu görülürken diğer zamanlarda fark yoktu (p<0.05). Cerrah memnuniyeti Grup PP’deki hastalara göre hem Grup PR ve hem de Grup PF’de daha iyiydi (p<0.05). Ayrıca Grup PR’de diğer gruplar ile karşılaştırıldığında daha erken derlenme sağlandı ve ek propofol ihtiyacı olanların sayısı diğer gruplardan daha azdı (p<0.05).Sonuç: Çalışmamızda propofol ile remifentanil; fentanil ve petidine göre daha erken derlenme ve yüksek cerrahi memnuniyet sağlamıştır.

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Cite This Article

Hakimoğlu, S., Davarcı, I., Tuzcu, K., Karcıoğlu, M., Gözükara, İ., Akkurt, Ç. B. Ö., Turhanoğlu, S. (2016). Comparison the Different Opioids with Propofol for Sedoanalgesia in D&C Operation. Interdisciplinary Medical Journal, Cilt: 7 - Sayı: 25, 10–18. https://ajindex.com/articles/887725

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