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Journals / Journal of Basic and Clinical Health Sciences / 2023 / Cilt: 7 - Sayı: 1

Is the Occurrence of Gestational Diabetes Mellitus in Pregnancies Higher Following In Vitro Fertilization Treatment? Why? A Retrospective Cohort Study

Nuran Nur AYPAR AKBAĞ
Merlinda ALUŞ TOKAT
Sevcan FATA
Elif ÜNSAL AVDAL
Emre OKYAY
Ömer Erbil DOĞAN
Pages
94–102
Publication Date
2023-01-31
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: As age and number of IVF trials increase in infertile women, the risk of GDM increases after IVF treatment.

📌 3 Key Takeaways

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Objective & Hypothesis:Purpose: This study aim to determine the occurrence of gestational diabetes mellitus (GDM) in pregnancies after IVF treatment and to evaluate the factors that reduce this risk.
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Key Findings & Data:Methods: This retrospective cohort study was conducted using the medical records of pregnant women who conceived following IVF at the in-vitro fertilization center between 2002–2019.
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Conclusion & Impact:Conclusion: As age and number of IVF trials increase in infertile women, the risk of GDM increases after IVF treatment.
🔬Design:Modeling & Simulation
📍Scope:2002–2019 Verileri
⚙️Variables:Gestational Diabetes Mellitus · In Vitro Fertilization · Risk Factors

Abstract

Purpose: This study aim to determine the occurrence of gestational diabetes mellitus (GDM) in pregnancies after IVF treatment and to evaluate the factors that reduce this risk. Methods: This retrospective cohort study was conducted using the medical records of pregnant women who conceived following IVF at the in-vitro fertilization center between 2002–2019. The data were obtained from medical records and phone interviews. Univariate and multivariate logistic regression analyses were performed. Results: The incidence of GDM was found to be 16.7%. The regression model indicated that the risk of GDM was 4.57 times higher in the age group 36–40 at conception during the IVF cycle than the age group 31–35 (95% CI = 1.18–17.73, p = .028). Furthermore, women who conceived after the second IVF trial had a risk of GDM 3.464 times higher than those that conceived after their first IVF trial (95% CI = 1.07–11.23, p= .038). Conclusion: As age and number of IVF trials increase in infertile women, the risk of GDM increases after IVF treatment.

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Cite This Article

AKBAĞ, N. N. A., TOKAT, M. A., FATA, S., AVDAL, E. Ü., OKYAY, E., DOĞAN, Ö. E. (2023). Is the Occurrence of Gestational Diabetes Mellitus in Pregnancies Higher Following In Vitro Fertilization Treatment? Why? A Retrospective Cohort Study. Journal of Basic and Clinical Health Sciences, Cilt: 7 - Sayı: 1, 94–102. https://ajindex.com/articles/879807

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References (15)

  1. McIntyre HD, Catalano P, Zhang C, Desoye G, Mathiesen ER, Damm P. Gestational diabetes mellitus. Nature Reviews Disease Primers 2019; 5:47
  2. International Diabetes Federation (IDF). IDF Diabetes Atlas. 8th ed. 2017
  3. Karaçam Z, Çelik D. The prevalence and risk factors of gestational diabetes mellitus in Turkey: a systematic review and meta-analysis. J Matern Fetal Neonatal Med 2019; 2:1-11
  4. Johns EC, Denison FC, Norman JE, Reynolds RM. Gestational Diabetes Mellitus: Mechanisms, Treatment, and Complications. Trends in Endocrinology & Metabolism 2018; 29 (11): 743-754
  5. Hoseini S, Hantoushzadeh S, Shoar S. Evaluating the extent of pregravid risk factors of gestational diabetes mellitus in women in Tehran. Iran Red Crescent Med J 2011; 13:407–14
  6. American Diabetes Association (ADA). Gestational diabetes mellitus. Diabetes Care 2004; 27(1): 88–90
  7. Allen C, Bowdin S, Harrison RF, et al. Pregnancy and perinatal outcomes after assisted reproduction: a comparative study. Ir J Med Sci 2008; 177:233–241
  8. Palomba S, Homburg R, Santagni S, La Sala GB, Orvieto R. Risk of adverse pregnancy and perinatal outcomes after high technology infertility treatment: a comprehensive systematic review. Reprod Biol Endocrinol 2016; 14(1):76
  9. Sabban H, Zakhari A, Patenaude V, Tulandi T, Abenhaim HA. Obstetrical and perinatal morbidity and mortality among in-vitro fertilization pregnancies: a population-based study. Arch Gynecol Obstet 2017; 296:107–113
  10. Storgaard M, Loft A, Bergh C, et al. Obstetric and neonatal complications in pregnancies conceived after oocyte donation: a systematic review and meta-analysis. BJOG 2017; 124:561–572
  11. Jones BJ, Zollner J, Haynes S, Cheng F, Dornhorst A. In vitro fertilization treatment influences glucose tolerance in multiple pregnancy. Diabetic Medicine 2013;30(2):252–254
  12. Ashrafi M, Gosili R, Hosseini R, Arabipoor A, Ahmadi J, Chehrazi M. Risk of gestational diabetes mellitus in patients undergoing assisted reproductive techniques. Eur J Obstet Gynecol Reprod Biol 2014; 176:149–152
  13. Zhu L, Zhang Y, Liu Y, et al. Maternal and live-birth outcomes of pregnancies following assisted reproductive technology: a retrospective cohort study. Sci Rep 2016; 6:35141
  14. Qin J, Liu X, Sheng X, Wang H, Gao S. Assisted reproductive technology and the risk of pregnancy-related complications and adverse pregnancy outcomes in singleton pregnancies: a metaanalysis of cohort studies. Fertil Steril 2016; 105(1):73–85
  15. Cai S,