Journals / Uludağ Üniversitesi Tıp Fakültesi Dergisi / 2022 / Cilt: 48 - Sayı: 3

Comparison of Stereotactic Body Radiotherapy Virtual Plans Obtained with Different Colimators in Cyberknife System in Partial Breast Irradiatıon: Retrospective Study

Parsiyel Meme Işınlamasında Cyberknife Sisteminde Farklı Kolimatörlerle Elde Edilen Stereotaktik Meme Radyoterapisi Sanal Planlarının Karşılaştırılması: Retrospektif Çalışma

Pages
293–299
Publication Date
2022-12-30
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

As a result of the comparison of the plans, a significant difference was found for MU and duration of treatment (p

📌 3 Key Takeaways

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Objective & Hypothesis:In our study, it was aimed to compare the volume of accelerated partial breast irradiation in patients diagnosed with early stage breast cancer in CyberKnife target and volume targeted virtual plans (APBI).
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Key Findings & Data:A virtual plan was created in CyberKnife system for 5 patients who received radiotherapy in our unit, 6 Gy per day for Iris, fixed and multi-leaf collimator (MLC) and 30 Gy in total.
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Conclusion & Impact:As a result of the comparison of the plans, a significant difference was found for MU and duration of treatment (p
🔬Design:Research Article
📍Scope:2026 Verileri
⚙️Variables:VMAT · ÇYK · CYBERKNIFE

Abstract

In our study, it was aimed to compare the volume of accelerated partial breast irradiation in patients diagnosed with early stage breast cancer in CyberKnife target and volume targeted virtual plans (APBI). A virtual plan was created in CyberKnife system for 5 patients who received radiotherapy in our unit, 6 Gy per day for Iris, fixed and multi-leaf collimator (MLC) and 30 Gy in total. Dosimetric parameters for three different collimators were analyzed according to the constraints of the NSABP-39/RTOG 0413 protocol. In the plans, it was ensured that critical organs were protected and PTV received 95% of the prescribed dose. The prescribed dose was defined by a minimum 80% isodose curve. Homogeneity index (HI), conformity index (CI), treatment time (min), monitor unit (MU) and doses received by critical organs were compared. The mean HI values for iris, fixed collimator, and MLC were 1.2- 1.2- 1.19, mean CI values were 1,08-1,06-1,07, mean treatment time was 47,6- 52,2- 25,4 (min) and MU values were found to be 19736,2-2026,.3- 7161,3 on average. Mean MU and duration of treatment were found in the lowest MLC. No significant difference was found for HI, CI. As a result of the comparison of the plans, a significant difference was found for MU and duration of treatment (p

Özet

Çalışmamızda erken evre meme kanseri tanılı hastalarda hızlandırılmış kısmı meme ışınlamasında (HKMI) CyberKnife (CK) tedavi cihazında yapılan sanal planlarda hedef hacim ve kritik organ dozlarının karşılaştırılması amaçlanmıştır. Birimimizde radyoterapi almış 5 hasta için CyberKnife sisteminde Iris, sabit ve çok yapraklı kolimatör (ÇYK) için günlük 6 Gy toplam 30 Gy olacak şekilde sanal plan oluşturuldu. Üç farklı kolimatör için dozimetrik parametreler NSABP-39/RTOG 0413 protokolündeki kısıtlamalara göre analiz edildi. Planlarda kritik organların korunması ve PTV’nin reçete edilen dozun % 95’ini alması sağlandı. Reçete edilen doz minimum % 80’lik izodoz eğrisine tanımlandı. Homojenite indeksi (Hİ), konformite indeksi (Kİ), tedavi süresi (dk), monitör unit (MU) ve kritik organların aldığı dozlar karşılaştırıldı. Iris, sabit kolimatör, ÇYK için sırasıyla Hİ değerleri ortalama 1,2- 1,2- 1,19, Kİ değerleri ortalama 1,08- 1,06- 1,07 tedavi süresi ortalama 47,6- 52,2- 25,4 (dk) ve MU değerleri ortalama 19736,2- 20267,3- 7161,3 olarak bulunmuştur. Planların karşılaştırılması sonucunda MU, tedavi süresi için anlamlı fark bulunmuştur (p

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Cite This Article

SARIBAŞ, Ö., ÇETİNTAŞ, S. K., KURT, M., ABAKAY, C. D., KAHRAMAN, A., ALTAY, A., İREM, Z. K., ÖZBEK, T. (2022). Comparison of Stereotactic Body Radiotherapy Virtual Plans Obtained with Different Colimators in Cyberknife System in Partial Breast Irradiatıon: Retrospective Study. Uludağ Üniversitesi Tıp Fakültesi Dergisi, Cilt: 48 - Sayı: 3, 293–299. https://ajindex.com/articles/874816

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References (11)

  1. Harbeck, N., Penault-Llorca, F., Cortes, et al. (2019). Breast cancer. Nat Rev Dis Primers, 5(1), 66
  2. Lazovich, D., Solomon, C. C., Thomas, D. B., Moe, R. E., White, E. (1999). Breast conservation therapy in the United States following the 1990 National Institutes of Health Consensus Development Conference on the treatment of patients with early stage invasive breast carcinoma. Cancer, 86 (4), 628-637
  3. Clarke, M., Collins, R., Darby, S., et al. Early Breast Cancer Trialists' Collaborative, G. (2005). Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: an overview of the randomised trials. Lancet, 366 (9503), 2087-2106
  4. Early Breast Cancer Trialists' Collaborative, G., Darby, S., McGale, P., Correa, et al. (2011). Effect of radiotherapy after breast-conserving surgery on 10-year recurrence and 15-year breast cancer death: meta-analysis of individual patient data for 10,801 women in 17 randomised trials. Lancet, 378 (9804), 1707-1716
  5. Nattinger, A. B., Hoffmann, R. G., Kneusel, R. T., Schapira, M. M. (2000). Relation between appropriateness of primary therapy for early-stage breast carcinoma and increased use of breast-conserving surgery. Lancet, 356 (9236), 1148-1153
  6. Group, S. T., Bentzen, S. M., Agrawal, R. K., et al. (2008). The UK Standardisation of Breast Radiotherapy (START) Trial B of radiotherapy hypofractionation for treatment of early breast cancer: a randomised trial. Lancet, 371 (9618), 1098-1107
  7. Whelan TJ, Pignol JP, Levine MN, et al. (2010). Long-term results of hypofractionated radiation therapy for breast cancer. N Engl J Med. 362, 513–20
  8. Touboul, E., Buffat, L., Belkacemi, Y., et al. (1999). Local recurrences and distant metastases after breast-conserving surgery and radiation therapy for early breast cancer. Int J Radiat Oncol Biol Phys, 43 (1), 25-38
  9. Veronesi, U., Marubini, E., Del Vecchio, M., et al. (1995). Local recurrences and distant metastases after conservative breast cancer treatments: partly independent events. J Natl Cancer Inst, 87 (1), 19-27
  10. Njeh, C. F., Saunders, M. W., Langton, C. M. (2010). Accelerated Partial Breast Irradiation (APBI): A review of available techniques. Radiat Oncol, 5, 90
  11. Rault, E., Lacornerie, T., Dang, H. P., Crop, F., Lartigau, E., Reynaert, N., Pasquier, D. (2016). Accelerated partial breast irradiation using robotic radiotherapy: a dosimetric comparison with tomotherapy and three-d