Journals / EMU Journal of Pharmaceutical Sciences / 2020 / Cilt: 3 - Sayı: 2

Evaluation of the recommended treatment and preventive measures of COVID-19

Pages
125–139
Publication Date
2020-10-31
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This review highlights current knowledge about the possible therapies, their mechanisms, safety considerations based on interventional trials, clinical data of in vitro studies and a patient response.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The COVID-19 pandemic is caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) that is continuing to spread around the world threatens the human health and has an impact on global economic crisis.
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Key Findings & Data:As of 26th July 2020, no dedicated FDA-approved treatment and vaccine strategies have been confirmed for the treatment and prevention of COVID-19 patients.
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Conclusion & Impact:This review highlights current knowledge about the possible therapies, their mechanisms, safety considerations based on interventional trials, clinical data of in vitro studies and a patient response.
🔬Design:Review & Systematic Survey
📍Scope:2020 Verileri
⚙️Variables:COVID-19 · in vitro studies · SARS-CoV-2

Abstract

The COVID-19 pandemic is caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) that is continuing to spread around the world threatens the human health and has an impact on global economic crisis. As of 26th July 2020, no dedicated FDA-approved treatment and vaccine strategies have been confirmed for the treatment and prevention of COVID-19 patients. Many ongoing clinical trials are in progress, and varieties of possible treatments are being tested around the globe. As a vital part of the healthcare system, doctors, nurses and pharmacists play an important role in providing guidelines of protection to the public not only to prevent and control the infection but also to develop treatment strategies and discover vaccine during the pandemic. Several countries around the world are in rush to discover a new and safe therapy and vaccine for novel coronavirus. This review highlights current knowledge about the possible therapies, their mechanisms, safety considerations based on interventional trials, clinical data of in vitro studies and a patient response.

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Cite This Article

KORDBACHEH, H., AYDIN, A., SANAJOU, S., ŞAHİN, G. (2020). Evaluation of the recommended treatment and preventive measures of COVID-19. EMU Journal of Pharmaceutical Sciences, Cilt: 3 - Sayı: 2, 125–139. https://ajindex.com/articles/829614

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References (6)

  1. de Abajo, Francisco J (2020). Use of Renin–Angiotensin–Aldosterone System Inhibitors and Risk of COVID-19 Requiring Admission to Hospital: A Case-Population Study. The Lancet 395(10238): 1705–14.
  2. Astuti I, Ysrafil (2020). Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2): An Overview of Viral Structure and Host Response. Diabetes Metab Syndr 14(4): 407–12.
  3. Atal, Shubham, Zeenat Fatima (2020). IL-6 Inhibitors in the Treatment of Serious COVID-19: A Promising Therapy. Pharm Med 1. Ayala A, Chung CS, Grutkoski PS, Song GY (2003). Mechanisms of Immune Resolution. Crit Care Med 31(8). Bikdeli B, Mahesh D, Liang T (2020). COVID-19 and Thrombotic or Thromboembolic Disease: Implications for Prevention, Antithrombotic Therapy, and Follow-Up. J Am Coll Cardiol 75(23): 2950–73.
  4. Brotherton H, Kalife S, Ahmadou L (2020). Dexamethasone for COVID-19: Data Needed from Randomised Clinical Trials in Africa. Burki T (2020). The Indirect Impact of COVID-19 on Women. The Lancet 20(8): 904–5. National Center for Health Statistics, Centers for Disease Control and Prevention (2020). Contact Tracing for COVID-19 | CDC. https://www.cdc.gov/coronavirus/2019-ncov/php/contact-tracing/contact-tracing-plan/contact-tracing.html (October, 18 2020) National Center for Health Statistics, Centers for Disease Control and Prevention (2020). How to Protect Yourself & Others https://www.cdc.gov/coronavirus/2019-ncov/prevent-getting-sick/prevention.html (October, 18 2020)
  5. Chandwani A, Shuter J (2008). Lopinavir/Ritonavir in the Treatment of HIV-1 Infection: Ther Clin Risk Manag 4(5): 1023–33.
  6. Costela-Ruiz VJ, Rebecca IM, Jose MP (2020). SARS-CoV-2 Infection: The Role of Cytokines in COVID-19 Disease. Cytokine Growth Factor Rev. David Norrie J (2020). Remdesivir for COVID-19: Challenges of Underpowered Studies. Dietz, Leslie. (2020). 2019 Novel Coronavirus (COVID-19) Pandemic: Built Environment Considerations To Reduce Transmission. mSystems 5(2). Fan Q, Bo Z, Jie M, Shuyang Z (2020). Safety Profile of the Antiviral Drug Remdesivir: An Update. Biomed Pharmacother 130: 110532. U.S. Food and Drug Administration FDA (2020). COVID-19 Update: FDA Broadens Emergency Use Authorization for Veklury (Remdesivir) to Include All Hospitalized Patients for Treatment of COVID-19 https://www.fda.gov/news-events/press-announcements/covid-19-update-fda-broadens-emergency-use-authorization-veklury-remdesivir-include-all-hospitalized (October 18, 2020) U.S. Food and Drug Administration FDA (2020) Recommend