On the other side, reactions concerhing both of 5-formyl uridine derivative with some halides, and 5-chlo- romethyl derivative of uridine with the previous aldehydes were also performed via Grignard reactions.
📌 3 Key Takeaways
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Objective & Hypothesis:2', 3'-0 isopropylidene-5-ammomethyl uridine was condensed with some aldehydes. in the şame time, reduçtion 44in situ” of the reaction products was achieved Ncvçrtheless, the resulting compounds showed to be unstable during chromatographic processes.
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Key Findings & Data:It was neces- sary, to increase their stability by suitable protection of their exo amino groups.
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Conclusion & Impact:On the other side, reactions concerhing both of 5-formyl uridine derivative with some halides, and 5-chlo- romethyl derivative of uridine with the previous aldehydes were also performed via Grignard reactions.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:SYNTHESİS · DERIVATIVES · URİDİNE
Abstract
2', 3'-0 isopropylidene-5-ammomethyl uridine was condensed with some aldehydes. in the şame time, reduçtion 44in situ” of the reaction products was achieved Ncvçrtheless, the resulting compounds showed to be unstable during chromatographic processes. It was neces- sary, to increase their stability by suitable protection of their exo amino groups. On the other side, reactions concerhing both of 5-formyl uridine derivative with some halides, and 5-chlo- romethyl derivative of uridine with the previous aldehydes were also performed via Grignard reactions.
AHMED, A. F. S. (1992). SYNTHESİS OF URİDİNE DERIVATIVES. Communications Faculty of Sciences University of Ankara Series B Chemistry and Chemical Engineering, Cilt: 38, 1–1. https://ajindex.com/articles/827547