Journals / Turkish Medical Student Journal / 2020 / Cilt: 7 - Sayı: 3

MYOCARDIAL INFARCTION DIAGNOSIS AND CARDIAC TROPONINS

Pages
159–170
Publication Date
2020-10-31
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

However, while using point-of-care cardiac troponin tests for the diagnosis of myocardial infarction, it should be kept in mind that these tests are less sensitive and more costly than tests performed in central laboratories

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Acute myocardial infarction is a condition that develops due to the blockage of blood flow to the heart.
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Key Findings & Data:Increases in cardiac troponin levels can be observed in many different disease states and do not necessarily indicate acute myocardial infarction.
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Conclusion & Impact:However, while using point-of-care cardiac troponin tests for the diagnosis of myocardial infarction, it should be kept in mind that these tests are less sensitive and more costly than tests performed in central laboratories
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Myocardial infarction · acute coronary syndrome · troponin

Abstract

Acute myocardial infarction is a condition that develops due to the blockage of blood flow to the heart. Serial electrocardiog- raphy follow-up should be performed in patients with suspected acute myocardial infarction, serum cardiac troponin levels should be measured, and this measurement should be repeated at regular intervals. Cardiac troponins are the main markers for the diagnosis of acute myocardial infarction, as they are sensitive and specific biochemical markers of myocardial cell necrosis. Elevated levels of cardiac troponins indicate cardiac damage, but it does not explain the cause of the damage. Increases in cardiac troponin levels can be observed in many different disease states and do not necessarily indicate acute myocardial infarction. It is necessary to check cardiac troponin levels in a patient admitted to the hospital in order to exclude other diseases before establishing the diagnosis of myocardial infarction. The one-hour “rule-in” and “rule-out” algorithms are used in the tests per- formed on patients who come to the emergency department with non-ST elevation myocardial infarction. In addition, there are point-of-care cardiac troponin tests that can be used in emergency services and ambulances. However, while using point-of-care cardiac troponin tests for the diagnosis of myocardial infarction, it should be kept in mind that these tests are less sensitive and more costly than tests performed in central laboratories

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Cite This Article

KURTOĞLU, B., ERKILIÇ, B., GÜRSEL, D. Y., ARSLAN, G., BACAKSIZOĞLU, O., ALTUNDAL, P., KARA, S., ARDIÇOĞLU, Y. (2020). MYOCARDIAL INFARCTION DIAGNOSIS AND CARDIAC TROPONINS. Turkish Medical Student Journal, Cilt: 7 - Sayı: 3, 159–170. https://ajindex.com/articles/809867

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References (13)

  1. Racek J, Rajdl D, editors. Clinical Biochemistry. 1st ed. Prague: Karolinum Press; 2016.p.296-8
  2. Duygu E, Kahraman N, Pehlivanoğlu S et al. Akut koroner sen- drom dışı olaylarda kardiyak troponin yüksekliğinin klinik önemi. Türk Kardiyoloji Dem Arş 2004;32:571-80
  3. Peela JR, Jarari AM, Hai A et al. Cardiac biomarkers: the tro- ponins and CK-MB. Ibnosina Journal of Medicine and Biomedical Sciences 2010;2(5):190-7
  4. Topol EJ. Chapter 13. In: Topol EJ, editor. Acute Coronary Syn- dromes. 3rd ed. Florida: CRC Press;2004.p.329-65
  5. Agewall S, Giannitsis E, Jernberg T et al. Troponin elevation in coronary vs. non-coronary disease. Eur Heart J 2011;32(4):404-11
  6. Alpert JS, Thygesen K, Antman E et al. Myocardial infarction redefined-a consensus document of The Joint European Society of Cardiology/American College of Cardiology Committee for the re- definition of myocardial infarction. J Am Coll Cardiol 2000;36:959- 69
  7. Kavsak PA, MacRae AR, Lustig et al. The impact of the ESC/ACC redefinition of myocardial infarction and new sensitive troponin assays on the frequency of acute myocardial infarction. Am Heart J 2006;152:118-25
  8. Braunwald E, Antman EM, Beasley JW et al. ACC/AHA 2002 guideline update for the management of patients with unstable an- gina and non-ST-segment elevation myocardial infarction-summa- ry article: a report of the American College of Cardiology/Ameri- can Heart Association task force on practice guidelines (committee on the management of patients with unstable angina). J Am Coll Cardiol 2002;40:1366-74
  9. Bassand JP, Hamm CW, Ardissino D et al. Guidelines for the di- agnosis and treatment of non-ST-segment elevation acute coronary syndromes. Task Force for Diagnosis and Treatment of Non-ST- Segment Elevation Acute Coronary Syndromes of European Soci- ety of Cardiology. Eur Heart J 2007;28:1598-660
  10. Celebi OO, Diker E, Aydogdu S. Kardiyak troponinlerin klinik önemi. Turk Kardiyol Dern Ars 2008 Jun;36(4):269-77
  11. Sheehan P, Vasikaran SD. The evolving clinical role of cardiac troponins and new acute myocardial infarction guidelines: implica- tions for the clinical laboratory. Clin Bichemist Rev 2001;23:52–65
  12. Wu AHB. Increased troponin in patients with sepsis and septic shock: myocardial necrosis or reversible myocardial depression? Intensive Care Med 2001;27:959-61
  13. Morrow DA, Rifai N, Tanasijevic MJ et al. Clinical efficacy of three assays for cardiac troponin I for risk stratification in acute coronary syndr