Journals / Sağlık Akademisyenleri Dergisi / 2022 / Cilt: 9 - Sayı: 3

The relationship between ovarian endometrosis and vitamin D level

Ovaryan endometrozis ve D vitamini düzeyi arasındaki ilişki

Pages
265–271
Publication Date
2022-09-01
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Conclusions: The correlation between vitamin D and endometriosis, which is the primary subject of the research, was investigated with three different statistical methods.

📌 3 Key Takeaways

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Objective & Hypothesis:ABSTRACT Introduction & Aim: The potential role of vitamin D in the pathogenesis of endometriosis is a subject that has been studied by researchers.
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Key Findings & Data:Results: According to the correlation analysis, there is a statistically significant, moderate relationship between the level of vitamin D in the blood and the stage.
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Conclusion & Impact:Conclusions: The correlation between vitamin D and endometriosis, which is the primary subject of the research, was investigated with three different statistical methods.
🔬Design:Modeling & Simulation
📍Scope:Comprehensive Sample
⚙️Variables:Endometriozis · D Vitamini · Anti-Müllerian Hormon

Abstract

ABSTRACT Introduction & Aim: The potential role of vitamin D in the pathogenesis of endometriosis is a subject that has been studied by researchers. This study was carried out to investigate the correlation between various features of endometriosis and vitamin D levels. Material Methods: Age, parity and smoking variables of the participants were examined as socio-demographic characteristics. Other variables examined in our study are stage, anti-Müllerian hormone and vitamin D levels, the side where endometriosis is seen, either right or left, the extent of endometriosis and infertility status. Descriptive statistical methods, correlation analysis, regression analysis, independent samples t-test and one-way analysis of variance were used. Results: According to the correlation analysis, there is a statistically significant, moderate relationship between the level of vitamin D in the blood and the stage. According to the regression model, vitamin D in the blood has a negative and significant effect on the stage. According to these findings, it can be said that the decrease in vitamin D level will increase the stage status of the patient. Conclusions: The correlation between vitamin D and endometriosis, which is the primary subject of the research, was investigated with three different statistical methods.

Özet

OVARYAN ENDOMETROZİSDE D VİTAMİNİ DÜZEYLERİ ÖZET Giriş ve Amaç: D vitamininin endometriozis patogenezindeki potansiyel rolü araştırmacılar tarafından üzerinde çalışılan bir konudur. Bu çalışma, endometriozisin çeşitli özellikleri ile D vitamini düzeyleri arasındaki ilişkiyi araştırmak amacıyla yapılmıştır. Gereç Yöntemler: Katılımcıların sosyodemografik özellikleri olarak yaş, parite ve sigara içme değişkenleri incelendi. Çalışmamızda incelenen diğer değişkenler evre, anti-Müllerian hormon ve D vitamini düzeyleri, endometriozisin, sağda veya solda, görüldüğü taraf, endometriozisin yaygınlığı ve infertilite durumudur. Tanımlayıcı istatistiksel yöntemler, korelasyon analizi, regresyon analizi, bağımsız örnekler t testi ve tek yönlü varyans analizi kullanılmıştır. Bulgular: Korelasyon analizine göre kandaki D vitamini düzeyi ile evre arasında istatistiksel olarak anlamlı, orta düzeyde bir ilişki vardır. Regresyon modeline göre kandaki D vitamininin evre üzerinde olumsuz ve anlamlı bir etkisi vardır. Bu bulgulara göre D vitamini seviyesindeki düşüşün hastanın evre durumunu yükselteceği söylenebilir. Sonuç: Araştırmanın birincil konusu olan D vitamini ile endometriozis arasındaki ilişki üç farklı istatistiksel yöntemle araştırıldı.

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Cite This Article

GURSOY, O., EREN, C. Y., GÜRER, H. G. (2022). The relationship between ovarian endometrosis and vitamin D level. Sağlık Akademisyenleri Dergisi, Cilt: 9 - Sayı: 3, 265–271. https://ajindex.com/articles/798250

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References (15)

  1. Chapron C, Marcellin L, Borghese B, Santulli P. (2019) Rethinking mechanisms, diagnosis and management of endometriosis. Nat Rev Endocrinol, 15(11):666–82
  2. Czyzyk A, Podfigurna A, Szeliga A, Meczekalski B. (2017) Update on endometriosis pathogenesis. Minerva Ginecol, 69(5):447–61
  3. Sizar O, Khare S, Goyal A, Bansal P, Givler A. (2022).Vitamin D Deficiency. StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing
  4. Kalaitzopoulos DR, Lempesis IG, Athanasaki F, Schizas D, Samartzis EP, Kolibianakis EM, et al. (2020) Association between vitamin D and endometriosis: a systematic review. Hormones (Athens), 19(2):109–21
  5. Han SJ, O’Malley BW. (2014) The dynamics of nuclear receptors and nuclear receptor coregulators in the pathogenesis of endometriosis. Hum Reprod Update, 20(4):467–84
  6. Harris HR, Chavarro JE, Malspeis S, Willett WC, Missmer SA. (2013) Dairy-food, calcium, magnesium, and vitamin D intake and endometriosis: a prospective cohort study. Am J Epidemiol, 177(5):420–30
  7. Giampaolino P, Della Corte L, Foreste V, Bifulco G. (2019) Is there a Relationship Between Vitamin D and Endometriosis? An Overview of the Literature. Curr Pharm Des, 25(22):2421–7
  8. Chauhan K, Shahrokhi M HM. (2021) Vitamin D. StatPearls. Treasure Island (FL): StatPearls Publishing
  9. La Marca A, Spada E, Grisendi V, Argento C, Papaleo E, Milani S, et al. (2012) Normal serum anti-Müllerian hormone levels in the general female population and the relationship with reproductive history. Eur J Obstet Gynecol Reprod Biol,163(2):180–4
  10. American Society for Reproductive Medicine. (1996) Revised American Society for Reproductive Medicine classification of endometriosis:. Fertil Steril,67(5):817–21
  11. Esinler I, Bozdag G, Arikan I, Demir B, Yarali H. (2012) Endometrioma ≤3 cm in Diameter per se Does Not Affect Ovarian Reserve in Intracytoplasmic Sperm Injection Cycles. Gynecol Obstet Invest,74(4):261–4
  12. La Marca A, Spada E, Grisendi V, Argento C, Papaleo E, Milani S, et al. (2015) Maternal age and risk of labor and delivery complications. Matern Child Health J,19(6):1202–11
  13. Ciavattini A, Serri M, Delli Carpini G, Morini S, Clemente N. (2017) Ovarian endometriosis and vitamin D serum levels. Gynecol Endocrinol, 33(2):164–7
  14. Derakhshan M, Derakhshan M, Hedayat P, Shiasi M, Sadeghi E. (2018) Vitamin D deficiency may be a modifiable risk factor in women with endometriosis. Crescent J Med Biol Sci, 5(4):292–6
  15. Qiu Y, Yuan S, Wang H. (2020) Vitami