AI Summary & Key Takeaways
AI InsightCONCLUSION When their familial histories of gastric complaints were detected, it is not necessary for H.pylori screening to be conducted in all children if also without any gastric symptoms.
📌 3 Key Takeaways
Abstract
Helicobacter pylori (H.pylori) was declared to be a "first-degree carcinogen" by WHO in 1994. It is usually transmitted during infancy and does not cause any symptoms in some people. Although the transmission of H. pylori has not understood completely yet, the principal reservoir appears to be family members. AİM The purpose of this retrospective study was investigated to the relationship between the presence of H.pylori infection in children and their parental history of gastric complaints. MATERIALS AND METHODS 612 children with gastric complaints (epigastric pain or dyspepsia), who underwent diagnostic esophagogastroduodenoscopy, were tested for H. pylori infection between 01.01.2012 and 31.12.2017. The diagnosis of H. pylori infection was made if histological examination was positive. The presence of gastric complaints in their parents was investigated. If there was no recorded knowledge about the history of gastric complaints in patient’s parents, the child was excluded from this retrospective study. A total of 196 children (56 male, 140 female, average age 14.9 ± 3.5 years, median age 15.0 years, range 4–18 years) were included to the study for retrospective analysis. The relationship between the presence of Helicobacter pylori infection in children and history of gastric complaints in their parents was reviewed retrospectively. The SPSS 21.0 was used to analyse the statistical data. A p value <0.05 was considered an indication of statistical significance. RESULTS 184 patients (93.9%) in 196 children had H. pylori infection. 106 of 196 (54.1%) children had parental history of gastric complaints. H.pylori infection rate was similar in the children with parental history of gastric complaints compared without parental history of gastric complaints (98 of 106, 92.5% vs 86 of 90, 95.6%). The rate of parental history of gastric complaints was also similar in H. pylori-infected children compared non-infected children (98 of 184, 53.3% vs 8 of 12, 66.7%). CONCLUSION When their familial histories of gastric complaints were detected, it is not necessary for H.pylori screening to be conducted in all children if also without any gastric symptoms.