Journals / Middle Black Sea Journal of Health Science / 2020 / Cilt: 6 - Sayı: 3

Classification of Prostate Cancer and Determination of Related Factors with Different Artificial Neural Network

Pages
325–332
Publication Date
2020-12-31
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In addition, estimating the significance values of factors associated with the disease with these classification models made it different from similar studies with the same dataset.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: In this study, it is aimed to classify prostate cancer, compare the predictions of these two models and determine the factors associated with the disease by applying Multilayer Perceptron Neural Network (MLPNN) and Radial-Based Function Neural Network (RBFNN) methods on the open access Prostate cancer dataset.Methods: In this study, the dataset named "Prostate Cancer Data Set" was used by obtaining from https://www.kaggle.com/sajidsaifi/prostate-cancer address.
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Key Findings & Data:The classification performance of the models was evaluated with the sensitivity, specificity, accuracy, negative predictive value and positive predictive value, which are among the classification performance metrics.
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Conclusion & Impact:In addition, estimating the significance values of factors associated with the disease with these classification models made it different from similar studies with the same dataset.
🔬Design:Modeling & Simulation
📍Scope:Comprehensive Sample
⚙️Variables:Prostate cancer · Multilayer perceptron neural network · Radial-based function neural network

Abstract

Objective: In this study, it is aimed to classify prostate cancer, compare the predictions of these two models and determine the factors associated with the disease by applying Multilayer Perceptron Neural Network (MLPNN) and Radial-Based Function Neural Network (RBFNN) methods on the open access Prostate cancer dataset.Methods: In this study, the dataset named "Prostate Cancer Data Set" was used by obtaining from https://www.kaggle.com/sajidsaifi/prostate-cancer address. To classify prostate cancer, MLPNN and RBFNN methods, which are artificial neural network models, is used. The classification performance of the models was evaluated with the sensitivity, specificity, accuracy, negative predictive value and positive predictive value, which are among the classification performance metrics. Prostate cancer related factors were estimated by using MLPNN and RBFNN models.Results: With the applied MLPNN model, performance metric values were obtained as AUC 0.937, Sensitivity 100%, accuracy 92.5%, Selectivity 84.6%, Positive predictive value 87.5% and Negative predictive value 100%. With the RBFNN model, the performance metric values were obtained as AUC 0.921, Sensitivity 83.3%, accuracy 86.6%, Selectivity 91.6%, Positive predictive value 93.7% and Negative predictive value 78.5%. When the effects of variables in the dataset in this study on prostate cancer are examined; The three most important variables for the MLPNN model were obtained as perimeter, area and compactness, respectively. For the RBFNN model, the three most important variables were obtained as perimeter, area and compactness, respectively.Conclusion: It was seen that MLPNN and RBFNN models used in this study gave successful predictions in the classification of prostate cancer. In addition, estimating the significance values of factors associated with the disease with these classification models made it different from similar studies with the same dataset.

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Cite This Article

ÇİÇEK, İ. B., KÜÇÜKAKÇALI, Z. (2020). Classification of Prostate Cancer and Determination of Related Factors with Different Artificial Neural Network. Middle Black Sea Journal of Health Science, Cilt: 6 - Sayı: 3, 325–332. https://ajindex.com/articles/791098

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