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Journals / Medical Research Reports / 2022 / Cilt: 5 - Sayı: 2

The Relationship Between Disease Severity and CRP/Prealbumin Ratio in Individuals Diagnosed with Obstructive Sleep Apnea Syndrome

Obstrüktis Uyku Apnesi Olan Hastalarda Hastalık Şiddeti ile CRP/Prealbümin Oranı Arasındaki İlişki

Yalçın BODUROĞLU
Duygu ZORLU
Bilal İLANBEY
Arzu ERTÜRK
Pages
49–61
Publication Date
2022-06-30
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

The CRP/PAB ratio had a weak positive correlation with the age, BMI, glucose, neutrophil, platelet and monocyte values and a weak negative correlation with the Hgb, MCH and MCHC values (p

📌 3 Key Takeaways

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Objective & Hypothesis:Introduction: Obstructive sleep apnea syndrome (OSAS) is a common sleep disorder.
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Key Findings & Data:Material and Methods: In this cross-sectional study, 99 patients with OSAS (mean age=54.34±10.3) were classified into three categories based on severity of OSAS into mild (n: 28 [28.3%]), moderate (n:23 [23.2%]), and severe (n:48 [48.5%]) based on AHI criteria.
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Conclusion & Impact:The CRP/PAB ratio had a weak positive correlation with the age, BMI, glucose, neutrophil, platelet and monocyte values and a weak negative correlation with the Hgb, MCH and MCHC values (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:CRP · CRP/Prealbumin · İnflamasyon

Abstract

Introduction: Obstructive sleep apnea syndrome (OSAS) is a common sleep disorder. Higher CRP levels has been found to rise in severe OSAS. The CRP/Prealbumin (CRP/PAB) ratio is a new index of risk of death and poor outcomes. We aimed to compare the CRP/PAB ratio with the severity of OSAS. Material and Methods: In this cross-sectional study, 99 patients with OSAS (mean age=54.34±10.3) were classified into three categories based on severity of OSAS into mild (n: 28 [28.3%]), moderate (n:23 [23.2%]), and severe (n:48 [48.5%]) based on AHI criteria. Results: The mean CRP/PAB ratios were similar among the groups (mild: 0.03± 0.03; moderate=0.02 ± 0.02; severe=0.03 ± 0.04; p=0.759). The demographic and baseline features were similar between the groups. The CRP/PAB ratio had a weak positive correlation with the age, BMI, glucose, neutrophil, platelet and monocyte values and a weak negative correlation with the Hgb, MCH and MCHC values (p

Özet

Giriş: Obstrüktif Uyku Apne Sendromu (OUAS) yaygın bir uyku hastalığıdır. Yüksek CRP düzeylerinin şiddetli OUAS durumunda yükseldiği saptanmıştır. CRP/Prealbümin (CRP/PAB) oranı ölüm riski ve kötü sonuçlar açısından yeni bir indekstir. CRP/PAB oranı ile OUAS şiddetini kıyaslanması amaçlanmıştır. Materyal ve Metod: Kesitsel bu çalışmada OUAS tanılı 99 hasta (ortalama yaş: 54.34±10.3) AHI kriterine dayalı olarak OUAS şiddeti durumuna göre hafif (n: 28 [28.3%]), orta (n:23 [23.2%]) ve şiddetli (n:48 [48.5%]) 3 sınıfa ayrılmıştır. Bulgular: Ortalama CRP/PAB oranı gruplar arasında benzer saptandı (hafif: 0.03± 0.03; orta: 0.02 ± 0.02, şiddetli: 0.03 ± 0.04, p=0.759). Demografik ve bazal özellikler gruplar arasında benzer saptandı. CRP/PAB oranı ile yaş, BMI, şeker, nötrofil, platelet ve monocit değerleri ile pozitif yönde ve Hgb, MCH, MCHC değerleri ile negatif yönde zayıf korelasyon saptandı (p

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Cite This Article

BODUROĞLU, Y., ZORLU, D., İLANBEY, B., ERTÜRK, A. (2022). The Relationship Between Disease Severity and CRP/Prealbumin Ratio in Individuals Diagnosed with Obstructive Sleep Apnea Syndrome. Medical Research Reports, Cilt: 5 - Sayı: 2, 49–61. https://ajindex.com/articles/789871

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