Journals / Journal of Health Sciences and Medicine / 2021 / Cilt: 4 - Sayı: 6

Complications with moderate-to-severe COVID-19 during hospital admissions in patients with pneumonia

Pages
766–771
Publication Date
2021-09-24
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Complications develop, especially in the management of COVID-19 pneumonia, which affect the treatment process and patient mobilization.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Introduction: Coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) is an infectious disease that has caused significant mortality and morbidity worldwide.
📊
Key Findings & Data:COVID-19 is known to cause complications, such as myocardial damage, acute coronary syndrome, deep vein thrombosis, pulmonary embolism, arrhythmia, heart failure, acute ischemic stroke, liver damage, cytokine storms, ischemia-reperfusion damage and side effects of drug treatments.
💡
Conclusion & Impact:Complications develop, especially in the management of COVID-19 pneumonia, which affect the treatment process and patient mobilization.
🔬Design:Research Article
📍Scope:2019 Verileri
⚙️Variables:complication · COVID-19 · pneumonia

Abstract

Introduction: Coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) is an infectious disease that has caused significant mortality and morbidity worldwide. COVID-19 is known to cause complications, such as myocardial damage, acute coronary syndrome, deep vein thrombosis, pulmonary embolism, arrhythmia, heart failure, acute ischemic stroke, liver damage, cytokine storms, ischemia-reperfusion damage and side effects of drug treatments. In our study, we aimed to evaluate the complications that developed during hospitalizations in patients with moderate-to-severe COVID-19 related pneumonia who were hospitalized in our COVID-19 service. Material and Method: This study included patients with moderate-to-severe COVID-19 pneumonia with a positive reverse transcriptase polymerase chain reaction (RT-PCR) test who were treated in our COVID-19 service between November 2020 and January 2021. Their demographic characteristics, treatment regimens, baseline laboratory values and complications during their hospitalization were retrospectively recorded. Results: The study group had a mean age of 62.92± 14.60 years and 40.6% (n= 55) were female. Approximately 35.3% (n= 48) of the patients developed complications due to COVID-19 during their follow-up period. Of the patients with complications, 63.8% (n: 30) were male, most common complications were elevated liver enzymes (47.9%) and pulmonary thromboembolism (20.8%). Of those patients with complications, the most common comorbidities were hypertension (40.4% [n= 19]), diabetes mellitus (25.5% [n=12]) and cardiovascular disease (23.4% [n=11]). There were no significant relationships between the presence of complications and age, sex or comorbid diseases (p>0.05 for each). Conclusion: There are more underlying conditions, such as hypertension, diabetes mellitus, cardiovascular disease, chronic lung disease in hospitalized patients with moderate-to-severe pneumonia compared to outpatients with COVID-19 pneumonia. Complications develop, especially in the management of COVID-19 pneumonia, which affect the treatment process and patient mobilization.

🔖

Cite This Article

ÖZDEMİREL, T. Ş., AKKURT, E. S., ERTAN, Ö., GÖKLER, M. E., ÖZYÜREK, B. A. (2021). Complications with moderate-to-severe COVID-19 during hospital admissions in patients with pneumonia. Journal of Health Sciences and Medicine, Cilt: 4 - Sayı: 6, 766–771. https://ajindex.com/articles/776709

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (12)

  1. Zhou F, Yu T, Du R, et al. Clinical course and risk factors for mortality of adult inpatients with CO- VID-19 in Wuhan, China: a retrospective cohort study. Lancet 2020; 395: 1054-62. Du Toit A. Outbreak of a novel coronavirus. Nat Rev Microbiol 2020; 18: 123. European Centre for Disease Prevention and Control. Q & A on COVID-19: Basic facts. Available from: https://www. ecdc.europa.eu/en/covid-19/facts/questions-answersbasic-facts Accessed date: 18 Sept 2020.
  2. Mahajan P, Dass B, Radhakrishnan N, McCullough PA. COVID-19-Associated Systemic Thromboembolism: A Case Report and Review of the Literature. Cardiorenal Med 2020; 10: 462-9.
  3. Boukhris M, Hillani A, Moroni F, et al. Cardiovascular Implications of the COVID-19 Pandemic: A Global Perspective. Can J Cardiol 2020; 36: 1068-80.
  4. Tian D, Ye Q. Hepatic complications of COVID-19 and its treatment. J Med Virol 2020; 92: 1818-24.
  5. Chen N, Zhou M, Dong X, et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. Lancet 2020; 395: 507-13.
  6. Zantah M, Dominguez Castillo E, Townsend R, Dikengil F, Criner GJ. Pneumothorax in COVID-19 disease- incidence and clinical characteristics. Respir Res 2020; 21: 236. Jin JM, Bai P, He W, et al. Gender differences in patients with COVID-19: focus on severity and mortality. Front Public Health 2020; 8: 152. Qiu P, Zhou Y, Wang F, et al. Clinical characteristics, laboratory outcome characteristics, comorbidities, and complications of related COVID-19 deceased: a systematic review and meta-analysis. Aging Clin Exp Res 2020; 32: 1869-78.
  7. Bertolini A, Van de Peppel IP, Bodewes FAJA, Moshage H, Fantin A, Farinati F. Abnormal liver function tests in patients with COVID-19: Relevance and Potential Pathogenesis. Hepatology 2020; 72: 1864-72.
  8. Zhang Y, Zheng L, Liu L, Zhao M, Xiao J, Zhao Q. Liver impairment in COVID-19 patients: A retrospective analysis of 115 cases from a single centre in Wuhan city, China. Liver Int 2020; 40: 2095-103.
  9. Cai Q, Huang D, Yu H, et al. COVID-19: Abnormal liver function tests. J Hepatol 2020; 73: 566-74.
  10. Fan Z, Chen L, Li J, et al. Clinical features of COVID-19-related liver damage. Clin Gastroenterol Hepatol 2020; 18: 1561-6.
  11. Porfidia A, Valeriani E, Pola R, Porreca E, Rutjes A, Di Nisio M. Venous thromboembolism in patients with COVID-19: Systematic review and meta-analysis. Thrombosis research 2020; 196: 67-74.
  12. Boonyawat K, Chantrathammachart P, Numthavaj P, et al. Incidence of th