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Journals / Journal of Health Sciences and Medicine / 2022 / Cilt: 5 - Sayı: 1

Evaluation of neutrophyl/lymphocyte ratio, platelet/lymphocyte ratio and mean platelet volume according to the disease activity index in patients of ankylosing spondylitis

Murat DOĞAN
Mehmet BOYACIOĞLU
Ayşe Gülşen DOĞAN
Pages
247–251
Publication Date
2022-01-17
DOI
—
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Conclusion: As a result of our study, NLR, PLR and MPV values are seen as simple, easy and inexpensive markers that can be used to determine disease activity in AS patients.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: To determine the relationship between neutrophil/lymphocyte ratio (NLR), platelet/ lymphocyte ratio (PLR) and mean platelet volume (MPV) with acute phase reactants in patients with ankylosing spondylitis (AS) and to show the usability of these parameters in the activation periods and follow-up of the disease.
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Key Findings & Data:Material and Method: The demographic data (age, gender) and Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) score of 70 patients who had been followed regularly for at least 1 year and whose diagnosis of AS was definite were recorded.
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Conclusion & Impact:Conclusion: As a result of our study, NLR, PLR and MPV values are seen as simple, easy and inexpensive markers that can be used to determine disease activity in AS patients.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Ankylosing spondylitis · NLR · PLR

Abstract

Objective: To determine the relationship between neutrophil/lymphocyte ratio (NLR), platelet/ lymphocyte ratio (PLR) and mean platelet volume (MPV) with acute phase reactants in patients with ankylosing spondylitis (AS) and to show the usability of these parameters in the activation periods and follow-up of the disease. Material and Method: The demographic data (age, gender) and Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) score of 70 patients who had been followed regularly for at least 1 year and whose diagnosis of AS was definite were recorded. The control group consists of 70 people who do not have any disease. Among the laboratory parameters, neutrophil, platelet, lymphocyte count, C-reactive protein(CRP), erythrocyte sedimentation rate(ESR), NLR, PLR and MPV values were retrospectively checked and recorded. Results: In our study, a statistically significant difference was found between the AS patients and the control group in MPV, NLR and PLR values. In addition, these values were found to be statistically significantly different between the groups with low disease activity and high disease activity in the AS patient group. There was a weak negative correlation between MPV value and BASDAI, ESR and CRP values. There was no statistically significant correlation between NLR value and ESR and CRP. There was no correlation between PLR value and ESR and CRP. Conclusion: As a result of our study, NLR, PLR and MPV values are seen as simple, easy and inexpensive markers that can be used to determine disease activity in AS patients.

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Cite This Article

DOĞAN, M., BOYACIOĞLU, M., DOĞAN, A. G. (2022). Evaluation of neutrophyl/lymphocyte ratio, platelet/lymphocyte ratio and mean platelet volume according to the disease activity index in patients of ankylosing spondylitis. Journal of Health Sciences and Medicine, Cilt: 5 - Sayı: 1, 247–251. https://ajindex.com/articles/776688

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