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Journals / Journal of Contemporary Medicine / 2021 / Cilt: 11 - Sayı: 4

Changes in non-culprit lesion severity on follow-up coronary angiography after primary percutaneous coronary ıntervention

Primer perkütan koroner girişimlerde sorumlu olmayan lezyonların kontrol koroner anjiyografide değişimleri

Fuat CANER
Selahattin TUREN
Aydın YILDIRIM
Pages
537–542
Publication Date
2021-07-31
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Significant exaggeration of non-culprit lesion stenosis severity occurs at the time of acute STEMI.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: Non-culprit lesion severity has often been exaggerated at the time of acute ST segment elevation myocardial infarction (STEMI).
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Key Findings & Data:Material and Methods: We retrospectively evaluated the changes in non-culprit lesion stenosis on follow-up CAG which was done within 2 months after primary percutaneous coronary intervention (P-PCI) in patients presenting with STEMI.
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Conclusion & Impact:Conclusion: Significant exaggeration of non-culprit lesion stenosis severity occurs at the time of acute STEMI.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Primer perkütan koroner girişim · çoklu damar hastalığı · sorumlu olmayan lezyon

Abstract

Aim: Non-culprit lesion severity has often been exaggerated at the time of acute ST segment elevation myocardial infarction (STEMI). We aimed to determine changes in non-culprit lesions severity on follow-up coronary angiography (CAG) and independent predictors of these changes. Material and Methods: We retrospectively evaluated the changes in non-culprit lesion stenosis on follow-up CAG which was done within 2 months after primary percutaneous coronary intervention (P-PCI) in patients presenting with STEMI. Results: 154 patients were included in this study and 207 non-culprit lesions (percentage diameter stenosis (PDS) ≥50%) were compared using quantitative coronary analyses (QCA). Minimal lumen diameter (1.30 ± 0.38 mm vs. 1.54 ± 0.46 mm, p<0.001) and reference vessel diameter (2.88 ± 0.66 mm vs. 2.92 ± 0.64 mm, p=0.001) were increased significantly and PDS (54.49 ± 9.38 vs. 47.5 ± 11.17, p<0.001) and percentage area stenosis (78.38 ± 8.65 vs. 71.29 ± 11.84, p= <0.001) were decreased significantly. There was no significant change in lesion length (13.52 ± 5.59 mm vs. 13.25 ± 5.31 mm, p= 0.078). 65 (31.4%) of these significant lesions (PDS ≥50% by QCA) were regressed (less than 50%) on follow-up CAG. In multivariable analyses; current smoking, clopidogrel use after the P-PCI and history of coronary artery disease were the independent predictors of decrease in PDS. Conclusion: Significant exaggeration of non-culprit lesion stenosis severity occurs at the time of acute STEMI.

Özet

Amaç: Akut ST segment yükselmeli miyokard enfarktüsü (STEMI) sırasında sorumlu olmayan lezyonlar sıklıkla olduklarından daha ciddi görünürler. Kontrol koroner anjiyografi (KAG)'de sorumlu olmayan lezyonların şiddetindeki değişiklikleri ve bu değişikliklerin bağımsız prediktörlerini belirlemeyi amaçladık. Gereç ve Yöntem: STEMI ile başvuran ve primer perkütan koroner girişimden (P-PKG) sonraki 2 ay içinde kontrol KAG yapılan hastalarda sorumlu olmayan lezyonlardaki değişiklikleri retrospektif olarak değerlendirdik. Bulgular: Bu çalışmaya 154 hasta dahil edildi ve 207 (yüzde çap darlığı (YÇD) ≥50%) sorumlu olmayan lezyon kantitatif koroner analizler (QCA) kullanılarak karşılaştırıldı. Minimal lümen çapı (1,30 ± 0,38 mm'ye karşı 1,54 ± 0,46 mm, p

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Cite This Article

CANER, F., TUREN, S., YILDIRIM, A. (2021). Changes in non-culprit lesion severity on follow-up coronary angiography after primary percutaneous coronary ıntervention. Journal of Contemporary Medicine, Cilt: 11 - Sayı: 4, 537–542. https://ajindex.com/articles/774991

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