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Journals / International Journal of Science Letters / 2021 / Cilt: 3 - Sayı: 2

Food Additives and Genotoxicity

Pınar ALTUNKAYNAK
Ece AVULOĞLU YILMAZ
Pages
109–120
Publication Date
2021-08-24
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

For this purpose, the keywords ‘‘food additive’’, ‘‘genotoxicity’’ were used together and research articles were included in this study.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:In today's changing conditions, there has been an increase in the consumption of ready-made food with the change in eating habits.
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Key Findings & Data:Moreover, parallel to the increase in ready-made food production, there has been an increase in the food additives used.
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Conclusion & Impact:For this purpose, the keywords ‘‘food additive’’, ‘‘genotoxicity’’ were used together and research articles were included in this study.
🔬Design:Review & Systematic Survey
📍Scope:2015-2021 Verileri
⚙️Variables:Food Additives · Genotoxicity · Genotoxicity Assays

Abstract

In today's changing conditions, there has been an increase in the consumption of ready-made food with the change in eating habits. Moreover, parallel to the increase in ready-made food production, there has been an increase in the food additives used. The dose amounts of food additives are determined as a result of experimental analyses. However, some additives show long-term toxic effects on the human body in genotoxicity tests. In this review, definition of substances, purposes of usage, classification, genotoxicity, definitions of tests and publications of genotoxicity studies in food additives were discussed. The search was conducted in peer-reviewed journals using Science-Direct, Web of Science and Google Scholar. In this study, genotoxicity studies conducted with food additives between 2015-2021 were complied. For this purpose, the keywords ‘‘food additive’’, ‘‘genotoxicity’’ were used together and research articles were included in this study.

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Cite This Article

ALTUNKAYNAK, P., YILMAZ, E. A. (2021). Food Additives and Genotoxicity. International Journal of Science Letters, Cilt: 3 - Sayı: 2, 109–120. https://ajindex.com/articles/768461

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References (11)

  1. Aledwany, A. Z., Basal, W. T., Al-Senosy, N. K., Issa, A. M. 2018. Assessment of genotoxicity of potassium nitrate and sodium benzoate in Drosophila melanogaster using smart and comet assays, Egyptian Academic Journal of Biological Sciences C, Physiology and Molecular Biology, 10(2): 83-97.
  2. Ataseven, N., Yüzbaşıoğlu, D., Keskin, A. Ç., Ünal, F. 2016.
  3. Genotoxicity of monosodium glutamate, Food and Chemical Toxicology, 91: 8-18.
  4. Ataseven, N., Yüzbaşioğlu, D., Ünal, F. Assessment of Food preservative potassium propionate (e283) genotoxicity in human peripheral blood lymphocytes using micronucleus test. The 3rd International Symposium on EuroAsian Biodiversity, 05-08 July 2017,
  5. Minsk- Belarus. Avuloglu-Yilmaz, E., Yuzbasioglu, D., Unal, F. 2020. In vitro genotoxicity assessment of monopotassium glutamate and magnesium diglutamate, Toxicology in Vitro, 65: 104780. Ayaz, A., Yurttagül, M. 2012.
  6. Toxic elements in food-II, Ankara Ministry of Health Publications, 727. Ayper, B. O. Ğ. A., & Binokay, S. 2010. Gıda katkı maddeleri ve sağlığımıza etkileri, Arşiv Kaynak Tarama Dergisi, 19(3): 141-154.
  7. Azqueta, A., Collins, A. R. 2013. The essential comet assay: a comprehensive guide to measuring DNA damage and repair, Archives of Toxicology, 87(6): 949-968.
  8. Bastaki, M., Farrell, T., Bhusari, S., Pant, K., & Kulkarni, R. 2017. Lack of genotoxicity in vivo for food color additive Allura Red AC, Food and Chemical Toxicology, 105: 308-314.
  9. Bellani, L., Muccifora, S., Barbieri, F., Tassi, E., Castiglione, M. R. Giorgetti, L. 2020. Genotoxicity of the food additive E171, titanium dioxide, in the plants Lens culinaris L. and Allium cepa L. Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 849: 503142. Bogar, F., Tuylu, B. 2019. Determination of genotoxic effects of some food additives with the help of CBMN technique, Fresenius Environmental Bulletin, 28(9): 6601-6611.
  10. Chassaing, B., Koren, O., Goodrich, J. K., Poole, A. C., Srinivasan, S., Ley, R. E., Gewirtz, A. T. 2015. Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome, Nature, 519(7541): 92-96.
  11. Cowan, T. E., Palmnas, M., Reimer, R., Ardell, K., Yang, J. J., Vogel, H., Shearer, J. 2013. Artificial sweetener consumption differentially affects the gut microbiota‐host metabolic interactions, The FASEB Journal, 27: 224.7-224.7. El-Hefny, I., Hozayen, W., Alsenosy, N., Basal, W., Ahmed, A., Diab, A. 2021. Evaluation of genotoxicity of three food preservatıves in Drosoph