Journals / Hacettepe Üniversitesi Eczacılık Fakültesi Dergisi / 2008 / Sayı: 2

Brine Shrimp Lethality Bioassay of Fumaria Densiflora Dc. and Fumaria Officinalis L. Extracts

Fumaria densiflora DC. ve Fumaria officinalis L. Ekstrelerinin Brine Shrimp Yöntemiyle Sitotoksik Aktivite Çalışmaları

Pages
125–132
Publication Date
2008-06-01
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The n-hexane and ethyl acetate extracts of Fumaria densiflora DC. and the n-hexane extract of F. officinalis L. showed cytotoxic activity against the brine shrimp.

📌 3 Key Takeaways

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Objective & Hypothesis:The cytotoxic activities of Herba Fumariae officinalis and Herba Fumariae densiflorae prepared from Fumaria officinalis L., growing wildly in Bağsaray Burdur and Fumaria densiflora DC., growing wildly in Kemalpaşa town Ulucak village İzmir , respectively were determined.
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Key Findings & Data:LC50 value of n-hexane, ethyl acetate, ethanol, methanol and water extracts of the plant materials were determined using brine shrimp Artemia salina lethality bioassay.
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Conclusion & Impact:The n-hexane and ethyl acetate extracts of Fumaria densiflora DC. and the n-hexane extract of F. officinalis L. showed cytotoxic activity against the brine shrimp.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Fumaria officinalis L. · Fumaria densiflora DC. · Brine Shrimp

Abstract

The cytotoxic activities of Herba Fumariae officinalis and Herba Fumariae densiflorae prepared from Fumaria officinalis L., growing wildly in Bağsaray Burdur and Fumaria densiflora DC., growing wildly in Kemalpaşa town Ulucak village İzmir , respectively were determined. LC50 value of n-hexane, ethyl acetate, ethanol, methanol and water extracts of the plant materials were determined using brine shrimp Artemia salina lethality bioassay. The n-hexane and ethyl acetate extracts of Fumaria densiflora DC. and the n-hexane extract of F. officinalis L. showed cytotoxic activity against the brine shrimp.

Özet

Bağsaray Burdur ’ dan toplanan Fumaria officinalis’ ten hazırlanan Herba Fumariae officinalis ve Kemalpaşa ilçesi Ulucak köyü İzmir ’ nden toplanan Fumaria densiflora DC. bitkisinden hazırlanan Herba Fumariae densiflorae droglarından hazırladığımız n-hegzan, etil asetat, etanol, metanol ve su ekstreleri üzerinde brine shrimp Artemia salina yöntemi ile sitotoksik aktivite tayini yapılmış ve LC50 değerleri hesaplanmıştır. F. densiflora DC.’ dan elde edilen n-hegzan ve etil asetat ekstresi ile F. officinalis L.’ den elde ettiğimiz n-hegzan ekstresi sitotoksik aktivite göstermiştir.

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Cite This Article

ERDOĞAN, T. F. (2008). Brine Shrimp Lethality Bioassay of Fumaria Densiflora Dc. and Fumaria Officinalis L. Extracts. Hacettepe Üniversitesi Eczacılık Fakültesi Dergisi, Sayı: 2, 125–132. https://ajindex.com/articles/762424

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